Hydroxyapatite/Silk Fibroin Composite Scaffold with a Porous Structure and Mechanical Strength Similar to Cancellous Bone by Electric Field-Induced Gel Technology DOI
Yun‐Fei Shao, Hui Wang,

Yiran Zhu

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(44), С. 60977 - 60991

Опубликована: Окт. 25, 2024

Repair and regeneration of bone tissue defects is a multidimensional process that has been highly challenging to date. The artificial scaffold materials, which play core role, still face the conflict biofriendly porous structure will reduce mechanical performance accelerate degradation. Herein, multistage structured hydroxyapatite (HA)/silk fibroin (SF) composite (e-HA/SF) was successfully constructed by cleverly utilizing electric field-induced gel technology. results indicated prepared e-HA/SF scaffolds possess biomimetic hierarchical structures with suitable porosity similar cancellous bone. HA nanocrystals were uniformly encapsulated in three-dimensional space scaffold, thus endowing an enhanced performance. Notably, maximum compression stress Young's modulus e-HA/SF-2 can reach 24.66 ± 0.88 28.91 3.19 MPa, respectively, are equivalent those Such enhancement previously unattainable through conventional freeze-drying strategies. Moreover, introduction bioactive nano-HA trigger optimal cell response both static dynamic culture experiments vitro. developed this study better balance between degradation properties scaffolds.

Язык: Английский

Review on application of silk fibroin hydrogels in the management of wound healing DOI

Chang Kuk You,

C. Wang,

Zhenjiang Ma

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 298, С. 140082 - 140082

Опубликована: Янв. 18, 2025

Язык: Английский

Процитировано

4

Silk fibroin for cosmetic dermatology DOI
Songjie Li, Han Chen,

Xin Dan

и другие.

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 159986 - 159986

Опубликована: Янв. 1, 2025

Процитировано

4

Toward the Production of Hydroxyapatite/Poly(Ether-Ether-Ketone) (PEEK) Biocomposites: Exploring the Physicochemical, Mechanical, Cytotoxic and Antimicrobial Properties DOI Open Access

Meirilany Rozeno Costa,

José Adeilton Carvalho Filho,

Carlos Bruno Barreto Luna

и другие.

Polymers, Год журнала: 2024, Номер 16(17), С. 2520 - 2520

Опубликована: Сен. 5, 2024

The development of hydroxyapatite (HAp) and polyether ether ketone (PEEK) biocomposites has been extensively studied for bone repair applications due to the synergistic properties involved materials. In this study, we aimed develop HAp/PEEK using high-energy ball milling, with HAp concentrations (20%, 40%, 60% w/v) in PEEK, evaluate their physicochemical, mechanical, cytotoxicity, antimicrobial potential Tissue Engineering (TE). were characterized by structure, morphology, apparent porosity, diametral compression strength, activity. study results demonstrated that successfully synthesized. C2 biocomposite, containing 40% HAp, stood out optimal distribution particles PEEK matrix, resulting higher strength (246 MPa) a homogeneous microstructure. It exhibited activity against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, no cytotoxicity observed. These make biocomposite promising regenerative medicine applications, combining mechanical bioactivity, biocompatibility.

Язык: Английский

Процитировано

4

Preparation of antibacterial tellurium nanorod-incorporated thermosensitive pluronic F-127 hydrogels for wound healing applications DOI
Yu‐Ting Chen, Anbazhagan Sathiyaseelan, Xin Zhang

и другие.

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 107107 - 107107

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

Mechanism of remediation of U(VI) contaminated simulated soil by AC‐nHAP gel microsphere as PRB combined electrokinetic technology DOI

Shukui Zhou,

Yuewu Yang,

Hui Tang

и другие.

Journal of Radioanalytical and Nuclear Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Окт. 4, 2024

Язык: Английский

Процитировано

0

Hydroxyapatite/Silk Fibroin Composite Scaffold with a Porous Structure and Mechanical Strength Similar to Cancellous Bone by Electric Field-Induced Gel Technology DOI
Yun‐Fei Shao, Hui Wang,

Yiran Zhu

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(44), С. 60977 - 60991

Опубликована: Окт. 25, 2024

Repair and regeneration of bone tissue defects is a multidimensional process that has been highly challenging to date. The artificial scaffold materials, which play core role, still face the conflict biofriendly porous structure will reduce mechanical performance accelerate degradation. Herein, multistage structured hydroxyapatite (HA)/silk fibroin (SF) composite (e-HA/SF) was successfully constructed by cleverly utilizing electric field-induced gel technology. results indicated prepared e-HA/SF scaffolds possess biomimetic hierarchical structures with suitable porosity similar cancellous bone. HA nanocrystals were uniformly encapsulated in three-dimensional space scaffold, thus endowing an enhanced performance. Notably, maximum compression stress Young's modulus e-HA/SF-2 can reach 24.66 ± 0.88 28.91 3.19 MPa, respectively, are equivalent those Such enhancement previously unattainable through conventional freeze-drying strategies. Moreover, introduction bioactive nano-HA trigger optimal cell response both static dynamic culture experiments vitro. developed this study better balance between degradation properties scaffolds.

Язык: Английский

Процитировано

0