Polydopamine-Coated Copper-Doped Mesoporous Silica/Gelatin–Waterborne Polyurethane Composite: A Multifunctional GBR Membrane Bone Defect Repair DOI Creative Commons
Mengmeng Jin, Mengmeng Jin,

Feiwu Kang

и другие.

Journal of Functional Biomaterials, Год журнала: 2025, Номер 16(4), С. 122 - 122

Опубликована: Апрель 1, 2025

Guided bone regeneration (GBR) membrane has proven to be a fundamental tool in the realm of defect repair. In this study, we develop mussel-inspired composite biomaterial through polydopamine-assisted, combining gelatin–WPU matrix with ion-release behavior Cu–MSNs for augmented regeneration. The optimized exhibits enhanced mechanical stability, demonstrating tensile strength 11.23 MPa (representing 2.3-fold increase compared Bio-Gide®), coupled significantly slower degradation kinetics that retained 73.3% structural integrity after 35-day immersion physiological solution. Copper ions act as angiogenic agents promote blood vessel growth and antimicrobial prevent potential infections. combined effect these components creates biomimetic environment is ideal cell adhesion, growth, differentiation. This research contributes development advanced biomaterials combine infection-prevention functions. It provides versatile effective solution treating injuries defects, offering new hope patients need.

Язык: Английский

Synthesis and characterization of a new smart magnetic nanocarrier for drug delivery DOI

Seyed Esmaeil Mohammadi Mehr,

Mehdi Faramarzi, Seyed Aboutaleb Mousavi Parsa

и другие.

Inorganic Chemistry Communications, Год журнала: 2025, Номер unknown, С. 114378 - 114378

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Polydopamine-Coated Copper-Doped Mesoporous Silica/Gelatin–Waterborne Polyurethane Composite: A Multifunctional GBR Membrane Bone Defect Repair DOI Creative Commons
Mengmeng Jin, Mengmeng Jin,

Feiwu Kang

и другие.

Journal of Functional Biomaterials, Год журнала: 2025, Номер 16(4), С. 122 - 122

Опубликована: Апрель 1, 2025

Guided bone regeneration (GBR) membrane has proven to be a fundamental tool in the realm of defect repair. In this study, we develop mussel-inspired composite biomaterial through polydopamine-assisted, combining gelatin–WPU matrix with ion-release behavior Cu–MSNs for augmented regeneration. The optimized exhibits enhanced mechanical stability, demonstrating tensile strength 11.23 MPa (representing 2.3-fold increase compared Bio-Gide®), coupled significantly slower degradation kinetics that retained 73.3% structural integrity after 35-day immersion physiological solution. Copper ions act as angiogenic agents promote blood vessel growth and antimicrobial prevent potential infections. combined effect these components creates biomimetic environment is ideal cell adhesion, growth, differentiation. This research contributes development advanced biomaterials combine infection-prevention functions. It provides versatile effective solution treating injuries defects, offering new hope patients need.

Язык: Английский

Процитировано

0