Polydopamine-Coated Copper-Doped Mesoporous Silica/Gelatin–Waterborne Polyurethane Composite: A Multifunctional GBR Membrane Bone Defect Repair DOI Creative Commons
Mengmeng Jin, Mengmeng Jin,

Feiwu Kang

et al.

Journal of Functional Biomaterials, Journal Year: 2025, Volume and Issue: 16(4), P. 122 - 122

Published: April 1, 2025

Guided bone regeneration (GBR) membrane has proven to be a fundamental tool in the realm of defect repair. In this study, we develop mussel-inspired composite biomaterial through polydopamine-assisted, combining gelatin–WPU matrix with ion-release behavior Cu–MSNs for augmented regeneration. The optimized exhibits enhanced mechanical stability, demonstrating tensile strength 11.23 MPa (representing 2.3-fold increase compared Bio-Gide®), coupled significantly slower degradation kinetics that retained 73.3% structural integrity after 35-day immersion physiological solution. Copper ions act as angiogenic agents promote blood vessel growth and antimicrobial prevent potential infections. combined effect these components creates biomimetic environment is ideal cell adhesion, growth, differentiation. This research contributes development advanced biomaterials combine infection-prevention functions. It provides versatile effective solution treating injuries defects, offering new hope patients need.

Language: Английский

Synthesis and characterization of a new smart magnetic nanocarrier for drug delivery DOI

Seyed Esmaeil Mohammadi Mehr,

Mehdi Faramarzi, Seyed Aboutaleb Mousavi Parsa

et al.

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114378 - 114378

Published: March 1, 2025

Language: Английский

Citations

0
Polydopamine-Coated Copper-Doped Mesoporous Silica/Gelatin–Waterborne Polyurethane Composite: A Multifunctional GBR Membrane Bone Defect Repair DOI Creative Commons
Mengmeng Jin, Mengmeng Jin,

Feiwu Kang

et al.

Journal of Functional Biomaterials, Journal Year: 2025, Volume and Issue: 16(4), P. 122 - 122

Published: April 1, 2025

Guided bone regeneration (GBR) membrane has proven to be a fundamental tool in the realm of defect repair. In this study, we develop mussel-inspired composite biomaterial through polydopamine-assisted, combining gelatin–WPU matrix with ion-release behavior Cu–MSNs for augmented regeneration. The optimized exhibits enhanced mechanical stability, demonstrating tensile strength 11.23 MPa (representing 2.3-fold increase compared Bio-Gide®), coupled significantly slower degradation kinetics that retained 73.3% structural integrity after 35-day immersion physiological solution. Copper ions act as angiogenic agents promote blood vessel growth and antimicrobial prevent potential infections. combined effect these components creates biomimetic environment is ideal cell adhesion, growth, differentiation. This research contributes development advanced biomaterials combine infection-prevention functions. It provides versatile effective solution treating injuries defects, offering new hope patients need.

Language: Английский

Citations

0