
Research Square (Research Square), Год журнала: 2023, Номер unknown
Опубликована: Окт. 19, 2023
Язык: Английский
Research Square (Research Square), Год журнала: 2023, Номер unknown
Опубликована: Окт. 19, 2023
Язык: Английский
Progress in Materials Science, Год журнала: 2025, Номер unknown, С. 101456 - 101456
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
2International Journal of Mechanical Sciences, Год журнала: 2024, Номер 281, С. 109566 - 109566
Опубликована: Июль 15, 2024
Язык: Английский
Процитировано
11Engineered Regeneration, Год журнала: 2025, Номер unknown
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
1npj Materials Degradation, Год журнала: 2024, Номер 8(1)
Опубликована: Апрель 24, 2024
Abstract The advent of additively manufactured biodegradable porous metals presents a transformative opportunity to meet the criteria ideal bone substitutes. Precisely tailoring their degradation behavior constitutes pivotal aspect this endeavor. In study, we investigated effects topological designs on profile laser powder bed fusion (LPBF) Zn scaffolds under dynamic in vitro immersion tests. Specifically, four types Zn-0.4Mn-0.2Mg (beam-based: diamond, face center cubic; surface-based: gyroid, schwarz-P) were designed and fabricated. mechanism was comprehensively evaluated using both experimental simulation methods. results illuminate profound impact structural design properties alloy scaffolds. beam-based diamond cubic exhibited rate 0.08–0.12 mm per year with relatively uniform mode immersion. On contrary, surface-based gyroid Schwarz-P demonstrated notably reduced due lower permeability. This restricted diffusion medium ions within pores, culminating accumulation products more severe localized degradation. study underscores potential as compelling strategy for scaffolds, thereby advancing suitability
Язык: Английский
Процитировано
5Composite Structures, Год журнала: 2024, Номер 340, С. 118210 - 118210
Опубликована: Май 14, 2024
Язык: Английский
Процитировано
4Computers in Biology and Medicine, Год журнала: 2024, Номер 177, С. 108630 - 108630
Опубликована: Май 20, 2024
Scaffolds are an essential component of bone tissue engineering to provide support and create a physiological environment for cells. Biomimetic scaffolds promising approach fulfill the requirements. Bone allografts widely used due their mechanical structural characteristics. The scaffold geometry is well known be important determinant induced stimulation felt by However, impact allograft on permeability wall shear stress distribution not understood. This information designing biomimetic that suitable cells proliferate differentiate. present study investigates effect at both macroscopic microscopic scales. Our results concluded was strongly correlated with porosity allograft. level local scale also determined surface curvature this can serve as guideline future designs favorable osteogenesis repair.
Язык: Английский
Процитировано
4Biomaterials, Год журнала: 2025, Номер 321, С. 123348 - 123348
Опубликована: Апрель 17, 2025
Язык: Английский
Процитировано
0Medical Engineering & Physics, Год журнала: 2025, Номер unknown, С. 104343 - 104343
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0Thin-Walled Structures, Год журнала: 2024, Номер unknown, С. 112800 - 112800
Опубликована: Дек. 1, 2024
Язык: Английский
Процитировано
3Progress in Biomedical Engineering, Год журнала: 2024, Номер 7(1), С. 012003 - 012003
Опубликована: Окт. 16, 2024
Abstract The design and optimization of bone scaffolds are critical for the success tissue engineering (BTE) applications. This review paper provides a comprehensive analysis computational methods scaffold architecture, focusing on balance between mechanical stability, biological compatibility, manufacturability. Finite element method (FEM), fluid dynamics (CFD), various algorithms discussed their roles in simulating refining designs. integration multiobjective topology has been highlighted developing that meet multifaceted requirements BTE. Challenges such as need consideration manufacturing constraints incorporation degradation regeneration models into process have identified. underscores potential advanced tools additive techniques evolving field BTE, aiming to improve patient outcomes regeneration. reliability current is examined, with suggestions incorporating non-deterministic approaches vivo validations enhance practical application optimized scaffolds. concludes call further research artificial intelligence-based advance optimization.
Язык: Английский
Процитировано
2