The effect of topological design on the degradation behavior of additively manufactured porous zinc alloy DOI Creative Commons
Yageng Li, Yixuan Shi, Wei Xu

и другие.

Research Square (Research Square), Год журнала: 2023, Номер unknown

Опубликована: Окт. 19, 2023

Abstract The advent of additively manufactured biodegradable porous metals presents a transformative opportunity to meet the criteria ideal bone substitutes. Precisely tailoring their degradation behavior constitutes pivotal aspect this endeavor. In study, for first time, we investigated effects topological designs on profile laser powder bed fusion (LPBF) Zn scaffolds under dynamic in vitro immersion tests. Specifically, four types Zn-0.4Mn-0.2Mg (beam-based: diamond, face center cubic; surface-based: gyroid, schwarz-P) were designed and fabricated. mechanism was comprehensively evaluated using both experimental simulation methods. results illuminate profound impact structural design properties alloy scaffolds. beam-based diamond cubic exhibited rate 0.5–0.8 mm/year with relatively uniform mode immersion. On contrary, surface-based gyroid Schwarz-P demonstrated notably reduced due lower permeability. This restricted diffusion medium ions within pores, culminating in accumulation products more severe localized degradation. study underscores potential as compelling strategy scaffolds, thereby advancing suitability

Язык: Английский

3D printed colloidal Aerogels: Principle, Process, Performance, and perspective DOI
Qingqing Cheng, Zhizhi Sheng, Yafei Ding

и другие.

Progress in Materials Science, Год журнала: 2025, Номер unknown, С. 101456 - 101456

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

2

Design exploration of staggered hybrid minimal surface magnesium alloy bone scaffolds DOI
Kun Li,

Ruobing Liao,

Qingcui Zheng

и другие.

International Journal of Mechanical Sciences, Год журнала: 2024, Номер 281, С. 109566 - 109566

Опубликована: Июль 15, 2024

Язык: Английский

Процитировано

11

Advances in Smart Hybrid Scaffolds: A Strategic Approach for Regenerative Clinical Applications DOI Creative Commons
Ahsan Riaz Khan,

Amol D. Gholap,

Navdeep Singh Grewal

и другие.

Engineered Regeneration, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

1

The effect of topological design on the degradation behavior of additively manufactured porous zinc alloy DOI Creative Commons
Yixuan Shi, Wei Xu, Haodong Che

и другие.

npj Materials Degradation, Год журнала: 2024, Номер 8(1)

Опубликована: Апрель 24, 2024

Abstract The advent of additively manufactured biodegradable porous metals presents a transformative opportunity to meet the criteria ideal bone substitutes. Precisely tailoring their degradation behavior constitutes pivotal aspect this endeavor. In study, we investigated effects topological designs on profile laser powder bed fusion (LPBF) Zn scaffolds under dynamic in vitro immersion tests. Specifically, four types Zn-0.4Mn-0.2Mg (beam-based: diamond, face center cubic; surface-based: gyroid, schwarz-P) were designed and fabricated. mechanism was comprehensively evaluated using both experimental simulation methods. results illuminate profound impact structural design properties alloy scaffolds. beam-based diamond cubic exhibited rate 0.08–0.12 mm per year with relatively uniform mode immersion. On contrary, surface-based gyroid Schwarz-P demonstrated notably reduced due lower permeability. This restricted diffusion medium ions within pores, culminating accumulation products more severe localized degradation. study underscores potential as compelling strategy for scaffolds, thereby advancing suitability

Язык: Английский

Процитировано

5

Inverse design of irregular architected materials with programmable stiffness based on deep learning DOI

Zhuoyi Wei,

Kai Wei,

Xujing Yang

и другие.

Composite Structures, Год журнала: 2024, Номер 340, С. 118210 - 118210

Опубликована: Май 14, 2024

Язык: Английский

Процитировано

4

Porosity and surface curvature effects on the permeability and wall shear stress of trabecular bone: guidelines for biomimetic scaffolds for bone repair DOI Creative Commons
Zhuang Xiong,

Léa Rouquier,

Xingrong Huang

и другие.

Computers in Biology and Medicine, Год журнала: 2024, Номер 177, С. 108630 - 108630

Опубликована: Май 20, 2024

Scaffolds are an essential component of bone tissue engineering to provide support and create a physiological environment for cells. Biomimetic scaffolds promising approach fulfill the requirements. Bone allografts widely used due their mechanical structural characteristics. The scaffold geometry is well known be important determinant induced stimulation felt by However, impact allograft on permeability wall shear stress distribution not understood. This information designing biomimetic that suitable cells proliferate differentiate. present study investigates effect at both macroscopic microscopic scales. Our results concluded was strongly correlated with porosity allograft. level local scale also determined surface curvature this can serve as guideline future designs favorable osteogenesis repair.

Язык: Английский

Процитировано

4

Optimal structural characteristics of osteoinductivity in bioceramics derived from a novel high-throughput screening plus machine learning approach DOI

Y Liu,

Quanle Cao,

Sheng-yi Yong

и другие.

Biomaterials, Год журнала: 2025, Номер 321, С. 123348 - 123348

Опубликована: Апрель 17, 2025

Язык: Английский

Процитировано

0

Gaussian Curvature-Mechanical Environment-Tissue Regeneration Relationships at the Bone-Implant Interface of Porous Implants: A Simulation Study DOI
Xing Peng, Dongyang He, Tongtong Shen

и другие.

Medical Engineering & Physics, Год журнала: 2025, Номер unknown, С. 104343 - 104343

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

Optimizing mass transfer performance in triply periodic minimal surface porous scaffolds through isosurface offset DOI
Kun Li, Chao Zuo,

Ruobing Liao

и другие.

Thin-Walled Structures, Год журнала: 2024, Номер unknown, С. 112800 - 112800

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

3

A review of computational optimization of bone scaffold architecture: Methods, challenges, and perspectives DOI Creative Commons
Ali H. Foroughi,

Caleb Valeri,

Mir Jalil Razavi

и другие.

Progress in Biomedical Engineering, Год журнала: 2024, Номер 7(1), С. 012003 - 012003

Опубликована: Окт. 16, 2024

Abstract The design and optimization of bone scaffolds are critical for the success tissue engineering (BTE) applications. This review paper provides a comprehensive analysis computational methods scaffold architecture, focusing on balance between mechanical stability, biological compatibility, manufacturability. Finite element method (FEM), fluid dynamics (CFD), various algorithms discussed their roles in simulating refining designs. integration multiobjective topology has been highlighted developing that meet multifaceted requirements BTE. Challenges such as need consideration manufacturing constraints incorporation degradation regeneration models into process have identified. underscores potential advanced tools additive techniques evolving field BTE, aiming to improve patient outcomes regeneration. reliability current is examined, with suggestions incorporating non-deterministic approaches vivo validations enhance practical application optimized scaffolds. concludes call further research artificial intelligence-based advance optimization.

Язык: Английский

Процитировано

2