The first report of triple anthelmintic resistance on a French Thoroughbred stud farm

International Journal for Parasitology Drugs and Drug Resistance, Год журнала: 2024, Номер 24, С. 100528 - 100528

Опубликована: Фев. 23, 2024

This study assessed the anthelmintic resistance in strongylid nematodes against commonly used (AH) drugs a French galloping racehorse stud farm from March to December 2023. Faecal egg count reduction tests (FECRTs) were conducted three different groups of Thoroughbred yearlings (a group 6 males, 13 females and 8 3 males) following new World Association for Advancement Veterinary Parasitology (WAAVP) guidelines. The efficacy fenbendazole was tested two once during monitoring period (in March), ivermectin twice March–April November–December) pyrantel one May–June). For each FECRT, 90% confidence interval percentage faecal calculated using hybrid Frequentist/Bayesian analysis method. strongylids observed fenbendazole, all which these tested. number animals sufficient reach ≥80% power test. results highlight first case triple AH France. Further studies involving more farms equids are required assess prevalence France refine recommendations owners.

Язык: Английский

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Assessing the benzimidazole resistance in equine strongyles by in vitro methods

Veterinary Parasitology, Год журнала: 2025, Номер 334, С. 110387 - 110387

Опубликована: Янв. 5, 2025

Язык: Английский

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Quantitative DNA metabarcoding reveals species composition of a macrocyclic lactone and pyrantel resistant cyathostomin population in the UK

International Journal for Parasitology Drugs and Drug Resistance, Год журнала: 2024, Номер 27, С. 100576 - 100576

Опубликована: Дек. 22, 2024

Язык: Английский

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Australian guidelines for equine internal parasite management

Australian Veterinary Journal, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

Over the past few decades, emergence of resistance amongst intestinal parasites horses to all available anthelmintic classes has emphasised need for a paradigm shift in parasite control approaches within Australian equine industry. Findings recent Australia‐wide research project have provided new insights into (i.e. strongyles and ascarids) from perspectives horse breeders veterinarians. The published data revealed trends prevalence distribution, breeders' veterinarians' attitudes on controlling internal parasites, efficacy commonly used products post‐treatment egg reappearance periods. These studies formed basis newly developed guidelines managing treating gastrointestinal nematodes horses. Tailored veterinarians, these contain information target risk factors their transmission, as well practical advice surveillance, choice, timing treatment, testing refugia. Guidelines Equine Internal Parasite Management (AGEIPM) will serve pocket companion providing best‐practice recommendations grounded locally conducted scientific research. Dissemination extension AGEIPM industry strengthen client–practitioner relationship. aim is reduce reliance blanket deworming management programs help curb progression limited

Язык: Английский

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Comparative phylogenetic and sequence identity analysis of internal transcribed spacer 2 and cytochrome C oxidase subunit I as DNA barcode markers for the most common equine Strongylidae species

Infection Genetics and Evolution, Год журнала: 2025, Номер unknown, С. 105729 - 105729

Опубликована: Фев. 1, 2025

Язык: Английский

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Common equine parasites: past, present and future

UK-Vet Equine, Год журнала: 2025, Номер 9(2), С. 66 - 73

Опубликована: Март 2, 2025

Parasites are ubiquitous in grazing equids, but most commonly cause infection without manifestation of clinical disease. However, the potential for profound and severe disease syndromes has historically prompted widespread adoption preventative control measures. With increasing development anthelmintic resistance, such measures must evolve change to more diagnostic-led, evidence-based programmes that consider specific epidemiology each target parasite. Through a background changing measures, this review explores equine parasites importance both past present, their manifestations, how picture common may future.

Язык: Английский

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Global equine parasite control guidelines: Consensus or confusion?

International Journal for Parasitology Drugs and Drug Resistance, Год журнала: 2025, Номер 28, С. 100600 - 100600

Опубликована: Июнь 3, 2025

Equine parasite control has historically been characterized by confusing and conflicting information, posing significant challenges for veterinarians horse owners to make evidence-based decisions. Since 2012, equine guidelines have developed published different parts of the world address this situation provide trusted sources current guidance. At 2024 International Infectious Disease Conference in Deauville, Normandy, France, lead authors guideline documents USA, UK, Sweden, Denmark, Netherlands, Australia, Europe convened presented their guidelines. This led a discussion differences similarities between an effort identify research needs area. In general, all recommend surveillance-based approach control, emphasizing importance anthelmintic resistance testing. Some focus on controlling Strongylus vulgaris, while others primarily cyathostomins, ascarids tapeworms. Although same four drug classes are marketed most countries, there some product portfolios available, notably Australia other countries. European countries various degrees prescription-only restrictions products, whereas products available over counter USA. Commercially diagnostic differed somewhat affected recommendations made as well. conclusion, general agreement based principles. One major challenge is communicating effectively end-users, which should be priority going forward.

Язык: Английский

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Understanding temporal and spatial distribution of intestinal nematodes of horses using faecal egg counts and DNA metabarcoding

Veterinary Parasitology, Год журнала: 2023, Номер 325, С. 110094 - 110094

Опубликована: Дек. 3, 2023

This study reports the spatial and temporal distribution of ascarid strongylid nematodes in Thoroughbred horses by age category across different climatic zones Australia over an 18-month period. Faecal samples (n = 2046) from individual were analysed using modified McMaster technique for faecal egg counts (FECs). Strongylids identified PCR-directed next-generation sequencing second internal transcribed spacer (ITS-2) nuclear ribosomal DNA. Yearlings had highest prevalence (82%) strongyle eggs followed weanlings (79%), foals (58%), wet mares (49%) dry (46%). For Parascaris spp., (35%) (21%) yearlings (10%). The mean FECs spp. observed (525 per gram [EPG] faeces) while those strongyles (962 EPG). Among that classified as adults at time sampling, 77% (860 1119) low (i.e., <250 EPG) egg-shedders. Mean FEC Mediterranean (818 summer (599 EPG), winter (442 non-seasonal (413 rainfall zones. Twenty-six nematode species detected, with Cylicostephanus longibursatus (26.5%), Cylicocyclus nassatus (23.7%) Coronocyclus coronatus (20.5%) being most frequently detected species. Their richness relative abundance varied horse age, season zone. In addition, Strongylus equinus Triodontophorus (T. brevicauda T. serratus) also detected. comprehensive elucidates (climatic zone) seasonal) trends burdens intestinal Australian non-invasive conventional molecular methods. information presented this is crucial developing integrated management strategies to control parasites farmed horses.

Язык: Английский

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Assessment of worm control practices recommended by equine veterinarians in Australia

Frontiers in Veterinary Science, Год журнала: 2023, Номер 10

Опубликована: Ноя. 3, 2023

This study aimed to assess Australian veterinarians’ knowledge, perceptions and treatment strategies for worm control in horses with an online questionnaire. The questionnaire comprised 64 questions covering various aspects of: (i) veterinary practice; (ii) the veterinarian’s knowledge of gastrointestinal nematodes (GINs) importance parasites different age groups horses; (iii) diagnosis worms; (iv) anthelmintics anthelmintic resistance (AR); (v) grazing management; (vi) means communication discussion between veterinarians their clients regarding control. Following a pilot survey, link survey was sent all ( n = 1,148) registered members Equine Veterinarians Australia April 2020. response rate 10% (118 1,148). findings this illustrate good understanding equine parasites, including However, respondents mainly recommended frequent, interval-based prophylactic deworming young horses, only 40% (96 239) diagnosed GIN infections based on faecal egg count (FEC) results horses. Furthermore, 27% (88 330) made decisions FECs. Most macrocyclic lactones (MLs) (71%, 481 677), most frequently used method calculate dose by estimating weight animals visually (53%, 63 118). Although majority (97%, 115 118) perceived AR be critical issue managing worms 58% (67 them were unaware status clients’ properties. Forty-two percent (50 presence worms, pinworms (16%), strongylins (15%), species Draschia Habronema (6%), Strongyloides westeri (2%) tapeworms (1%). Twenty-seven (32 rarely discussed practices clients. provides insights into perception manage parasites. highlight continued education awareness AR, use non-chemical methods as well consideration legislation prescription-only FECs achieve sustainable GINs

Язык: Английский

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Worm control practices used by Thoroughbred horse managers in Australia: A national survey

Veterinary Parasitology, Год журнала: 2024, Номер 327, С. 110116 - 110116

Опубликована: Янв. 13, 2024

This study assessed worm control practices used by Australian Thoroughbred farm managers with an online questionnaire survey. The comprised 52 questions (close-ended: 44; open-ended: 8) about demography and general husbandry practices, managers' knowledge of gastrointestinal nematodes (GIN) their importance, diagnosis, strategies anthelmintics, anthelmintic resistance (AR) grazing management. Following the pilot survey, link for survey was sent to all (n = 657) registered members Breeders Australia on 12th April 2020. response rate 18.5% (122 675). reported a good understanding GIN parasite importance in different age groups horses as most respondents (70% 122) perceived worm-related illness be more important young (i.e., foals, weanlings yearlings) than adult (> 3 years old) horses. Although (93%, 113 anthelmintics prophylactically GIN, only 15% (18 observed Just under 40% were performing faecal egg counts, less 20% using results counts guide deworming decisions. interval-based strategy common method (≥55% 122 respondents) Macrocyclic lactones first choice majority (88%, 107 against commonly issue managing worms horses, 29% efficacy 91% (111 unaware AR properties. Grazing management such manure removal, frequently performed smaller paddocks (<0.20 ha: 58%) larger (>0.20 18%). Multiple correspondence analyses showed that likelihood suboptimal small farms ≤50 horses) greater medium 51-100) large >100) farms. provides insights into Australia, stud worms, options concerns, thereby paving way taking any initiatives address problem

Язык: Английский

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