Synthesis and Characterization of Cu-Vanadate Doped Hydroxyapatite Nanoparticles: Morphological, Structural, and Stability for Biomedical Use
Journal of the Australian Ceramic Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 6, 2025
Язык: Английский
Superhydrophililc tin doped hyrdoxyapatite films using Galatea paradoxa shells
Surface and Coatings Technology,
Год журнала:
2025,
Номер
unknown, С. 132087 - 132087
Опубликована: Март 1, 2025
Язык: Английский
Macromolecule-based stem cell and cell-free strategies for oral and maxillofacial tissue repair
Materials & Design,
Год журнала:
2024,
Номер
244, С. 113203 - 113203
Опубликована: Июль 29, 2024
The
oral
and
maxillofacial
regions
perform
mastication,
swallowing,
speech,
expression;
therefore,
tissue
defects
can
seriously
affect
patient
physical
mental
health.
Biomaterials
be
used
to
repair
defects.
However,
traditional
biomaterials
lack
biocompatibility
cannot
accurately
match
the
shape
of
damaged
tissues,
leading
immune
rejection
chronic
inflammation,
thereby
limiting
their
ability.
improve
mesenchymal
stem
cell
(MSC)
survival
by
simulating
extracellular
matrix
(ECM).
MSCs
have
excellent
self-regenerative
abilities
differentiate
into
almost
all
types,
making
them
valuable
for
engineering.
This
review
summarizes
biomaterial-based,
cell,
cell-free
therapies
discusses
properties,
advantages,
disadvantages,
application
mechanisms,
with
a
particular
focus
on
use
in
defect
regeneration
limitations
current
materials
strategies.
provides
insights
using
regeneration.
Язык: Английский
True-bone-ceramics / type I collagen scaffolds for repairing osteochondral defect
Journal of Materials Science Materials in Medicine,
Год журнала:
2024,
Номер
36(1)
Опубликована: Дек. 30, 2024
In
recent
years,
the
incidence
of
cartilage
defects
has
increased
dramatically,
and
its
etiology
is
complex
varied.
Osteochondritis
dissecans
(OCD),
as
one
main
etiologies,
damages
both
bone
tissues
can
progress
to
severe
osteoarthritis,
which
been
difficult
problems
for
clinicians.
The
vigorous
development
material
science
tissue
engineering
provides
new
ideas
treatment
OCD,
in
selection
scaffold
materials
particularly
important.
this
study,
true-bone-ceramics
(TBC),
good
mechanical
strength
osteoconductivity,
type
I
collagen
(COL1),
excellent
biocompatibility,
were
chosen
co-construct
TBC/COL1
osteochondral
repair.
order
ensure
most
appropriate
coating
concentration,
three
experimental
groups
(1,
5,
12
mg/ml)
set
up.
Through
physicochemical
property
test,
biocompatibility
analysis
vivo
implantation
experiments
composite
scaffolds,
mg/ml
scaffolds
present
best
repair
effect
among
groups.
Язык: Английский
Advances in Antibiotic-Loaded Nanofibers for the Treatment of Bone Infections: A Review
Pharmacon Jurnal Farmasi Indonesia,
Год журнала:
2024,
Номер
unknown, С. 161 - 175
Опубликована: Дек. 31, 2024
Antibiotic-loaded
nanofiber-based
drug
delivery
systems
represent
a
novel
approach
to
treating
complex
bone
infections,
particularly
osteomyelitis
caused
by
antibiotic-resistant
bacteria
such
as
Methicillin-resistant
Staphylococcus
aureus
(MRSA).
These
offer
localized,
sustained
release,
significantly
reducing
systemic
side
effects
and
mitigating
the
development
of
antibiotic
resistance.
This
review
evaluates
advancements
in
electrospun
nanofibers
with
biodegradable
polymers
like
Poly(lactic-co-glycolic
acid)
(PLGA)
Polycaprolactone
(PCL),
which
ensure
controlled
release
while
supporting
regeneration.
A
systematic
search
using
PRISMA
guidelines
across
ScienceDirect
ACS
Publication
databases
(2020-2024)
identified
42
relevant
studies.
The
inclusion
bioactive
agents
hydroxyapatite
was
found
enhance
antibacterial
properties
accelerate
tissue
demonstrates
that
antibiotic-loaded
promising,
targeted
therapeutic
alternative
conventional
treatments,
for
similar
challenging
infections.
Future
research
directions
will
focus
on
optimizing
nanofiber
compositions
functionalities
better
meet
clinical
needs,
ensuring
more
efficient
personalized
management
severe
Язык: Английский
Nanomaterial-functionalized electrospun scaffolds for tissue engineering
Journal of Biomaterials Science Polymer Edition,
Год журнала:
2024,
Номер
unknown, С. 1 - 43
Опубликована: Сен. 11, 2024
Tissue
engineering
has
emerged
as
a
biological
alternative
aimed
at
sustaining,
rehabilitating,
or
enhancing
the
functionality
of
tissues
that
have
experienced
partial
complete
loss
their
operational
capabilities.
The
distinctive
characteristics
electrospun
nanofibrous
structures,
such
elevated
surface-area-to-volume
ratio,
specific
pore
sizes,
and
fine
fiber
diameters,
make
them
suitable
effective
scaffolds
in
tissue
engineering,
capable
mimicking
functions
targeted
tissue.
However,
nanofibers,
whether
derived
from
natural
synthetic
polymers
combinations,
often
fall
short
replicating
multifunctional
attributes
extracellular
matrix
(ECM).
To
address
this,
nanomaterials
(NMs)
are
integrated
into
polymeric
through
various
functionalization
techniques
to
enhance
properties.
Incorporation
NMs
imparts
unique
features,
including
high
surface
area,
superior
mechanical
properties,
compositional
variety,
structural
adaptability,
exceptional
porosity,
enhanced
capabilities
for
promoting
cell
migration
proliferation.
This
review
provides
comprehensive
overview
types
NMs,
methodologies
used
integration
scaffolds,
recent
advancements
NM-functionalized
regenerating
bone,
cardiac,
cartilage,
nerve,
vascular
tissues.
Moreover,
main
challenges,
limitations,
prospects
elaborated.
Язык: Английский