Advances in Clinical Medicine, Год журнала: 2025, Номер 15(03), С. 2357 - 2368
Опубликована: Янв. 1, 2025
Язык: Английский
International Journal of Women s Health, Год журнала: 2022, Номер Volume 14, С. 395 - 404
Опубликована: Март 1, 2022
Background: Since the emergence of COVID-19 vaccinations, many women around world are reporting abnormalities in their menstrual periods post-vaccination. The aim this study is to investigate prevalence and impact after vaccine among females residing within Middle East North Africa (MENA). Methods: utilized a cross-sectional online self-administered survey from July 2021 August targeting living MENA region above age menarche who had received were not pregnant or lactating, do have history primary ovarian insufficiency, hypothalamic menopause, undergone hysterectomy. was distributed regionally via social media. Results: A total 2269 included our study, with mean 34.3 ± 8.5 years. About 66.3% participants reported symptoms post-vaccination, which 46.7% experienced them first dose. However, 93.6% participants, resolved 2 months. Vaccine type did significantly influence incidence (p > 0.05). Participants confirmed previous infection very similar percentage compared people suspected test (67.5%, 66.8%, respectively); nevertheless, those general side effects more < 0.001). Compared pandemic status, Conclusion: showed possible link between that impacted quality life. Keywords: COVID-19, MENA, abnormalities, cycle,
Язык: Английский
Процитировано
159
Open Medicine, Год журнала: 2022, Номер 17(1), С. 475 - 484
Опубликована: Янв. 1, 2022
We investigated menstrual irregularities after the first and second doses of COVID-19 vaccine. Women answered a customised online questionnaire (ClinicalTrial.gov ID: NCT05083065) aimed to assess vaccine type, phase cycle during which was administered, occurrence doses, how long this effect lasted. excluded women with gynaecological non-gynaecological diseases, undergoing hormonal non-hormonal treatments, in perimenopause or menopause, as well those who had irregular cycles last 12 months before administration. According our data analysis, approximately 50-60% reproductive-age received dose reported irregularities, regardless type administered The seems be slightly higher (60-70%) dose. Menstrual both were found self-resolve half cases within two months. Based on these results, we suggest consider elements counselling receive vaccine, letting them know about potential temporary self-limiting subsequent month(s).
Язык: Английский
Процитировано
131
Frontiers in Reproductive Health, Год журнала: 2022, Номер 4
Опубликована: Июль 25, 2022
COVID-19 vaccination protects against the potentially serious consequences of SARS-CoV-2 infection, but some people have been hesitant to receive vaccine because reports that it could affect menstrual bleeding. To determine whether this occurs we prospectively recruited a cohort 79 individuals, each whom recorded details at least three consecutive cycles, during which time they received one dose vaccine. In spontaneously cycling participants, was associated with delay next period, change reversed in subsequent unvaccinated cycles. No detected those taking hormonal contraception. explore hypotheses about mechanism by these changes occur, retrospectively larger cohort, 1,273 who had kept record their cycle and dates. found trend toward use combined contraception being protective reporting delayed suggesting following may be mediated perturbations ovarian hormones. However, were unable detect clear association between timing within changes. Our findings suggest can lengthen effect Importantly, find returns its pre-vaccination length
Язык: Английский
Процитировано
74
BMJ Medicine, Год журнала: 2022, Номер 1(1), С. e000297 - e000297
Опубликована: Сен. 1, 2022
Objectives To identify whether covid-19 vaccines are associated with menstrual changes in order to address concerns about cycle disruptions after vaccination. Design Global, retrospective cohort study of prospectively collected data. Setting International users the tracking application, Natural Cycles. Participants 19 622 individuals aged 18-45 years lengths 24-38 days and consecutive data for at least three cycles before one covid (vaccinated group; n=14 936), those four over a similar time period (unvaccinated n=4686). Main outcome measures The mean change within was assessed by vaccination group menses length (mean first second dose vaccine subsequent cycle). Mixed effects models were used estimate adjusted difference between vaccinated unvaccinated. Results Most people (n=15 713; 80.08%) younger than 35 years, from UK (n=6222; 31.71%), US Canada (28.59%), or Europe (33.55%). Two thirds (9929 (66.48%) 14 936) received Pfizer-BioNTech (BNT162b2) vaccine, 17.46% (n=2608) Moderna (mRNA-1273), 9.06% (n=1353) Oxford-AstraZeneca (ChAdOx1 nCoV-19), 1.89% (n=283) Johnson & (Ad26.COV2.S). Individuals who had less day increase their cycles, compared not (0.71 (99.3% confidence interval 0.47 0.96) dose; 0.56 (0.28 0.84) dose). larger two doses (3.70 (2.98 4.42)). One vaccination, per (0.02 −0.10 0.14), but yet (0.85 0.24 1.46)) unvaccinated individuals. Changes did differ vaccine’s mechanism action (mRNA, adenovirus vector, inactivated virus). Menses unaffected Conclusions Covid-19 is small likely be temporary no length.
Язык: Английский
Процитировано
71
Vacunas, Год журнала: 2022, Номер 23, С. S77 - S87
Опубликована: Июль 19, 2022
Язык: Английский
Процитировано
68
Women s Health, Год журнала: 2022, Номер 18
Опубликована: Янв. 1, 2022
Menstrual disorders were not reported as a possible secondary effect in any of the clinical trials for SARS-CoV-2 vaccines.
Язык: Английский
Процитировано
60
Frontiers in Rehabilitation Sciences, Год журнала: 2023, Номер 4
Опубликована: Апрель 28, 2023
Long COVID disproportionately affects premenopausal women, but relatively few studies have examined COVID's impact on female reproductive health. We conduct a review of the literature documenting health impacts which may include disruptions to menstrual cycle, gonadal function, ovarian sufficiency, menopause, and fertility, as well symptom exacerbation around menstruation. Given limited research, we also overlapping associated illnesses including myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), postural orthostatic tachycardia (POTS), connective tissue disorders like Ehlers-Danlos (EDS), endometriosis, these help elucidate conditions in COVID. These illnesses, whose patients are 70%–80% increased rates dysmenorrhea, amenorrhea, oligomenorrhea, dyspareunia, infertility, vulvodynia, intermenstrual bleeding, cysts, uterine fibroids pelvic congestion syndrome, gynecological surgeries, adverse pregnancy complications such preeclampsia, maternal mortality, premature birth. Additionally, symptoms can be impacted by pregnancy, menopause. propose priorities for future research healthcare based literature. screening comorbid conditions; studying menopause illness progression; uncovering role sex differences hormones illnesses; addressing historical inequities that contributed detrimental knowledge gaps this patient population.
Язык: Английский
Процитировано
43
Vaccine, Год журнала: 2023, Номер 41(36), С. 5271 - 5282
Опубликована: Июль 3, 2023
Many signals of menstrual disturbances as possible side effects vaccination against COVID-19 have been reported. Our objective was to compare the risk before and after among women aged 18-30 years in Oslo, Norway. We used electronic questionnaires collect reports from 3972 years, participating population-based Norwegian Young Adult Cohort. examined occurrence (heavier bleeding than usual, prolonged bleeding, shorter interval between menstruations, longer spot bleedings, stronger pain during menstruation, period without bleeding) first second dose vaccine. Relative risks (RR) according were estimated using a self-controlled case-series design. performed additional analyses stratified by vaccine brand, contraception/hormone use, presence gynecological condition(s). The prevalence any disturbance 36.7% last cycle prior dose. RR for heavier usual 1.90 (95% CI: 1.69-2.13) 1.84 (1.66-2.03) Increased menstruation also observed both doses. RRs did not differ with or condition(s) disturbances. Menstrual common regardless vaccination. found increased vaccination, particularly pain. In future, characteristics should be included trials.
Язык: Английский
Процитировано
22
Journal of Infection and Public Health, Год журнала: 2023, Номер 16(5), С. 697 - 704
Опубликована: Март 2, 2023
COVID - 19 vaccine can lead to various local and systemic side effects, including menstrual irregularities in women. There is no robust quantitative evidence of the association between irregularities. A meta-analysis was performed estimate pooled prevalence a range disorders that may occur women following vaccination.After searching for epidemiological studies, we systematically on PubMed/Medline, EMBASE, Science Direct. Sixteen studies were finally included study. We estimated corresponding 95 % confidence intervals (CIs) group disorders, menorrhagia, polymenorrhea, abnormal cycle length, oligomenorrhea. Heterogeneity assessed using I2 statistic Q test.Overall, menorrhagia 24.24 (pooled %; CI: 12.8-35.6 %). The polymenorrhea 16.2 prevalence: 10.7-21.6 length relatively lower than other 6.6 5.0-8.2 oligomenorrhea 22.7 (95 13.5-32.0 %).The findings indicate oligomenorrhea, most common after vaccination. also suggest high proportion suffer from Further longitudinal are needed confirm causal relationship COVID-19 vaccination
Язык: Английский
Процитировано
20
BMJ Sexual & Reproductive Health, Год журнала: 2024, Номер 50(3), С. 212 - 225
Опубликована: Июнь 10, 2024
Menstrual health is a key patient-reported outcome beyond its importance as general indicator of and fertility. However, menstrual function was not measured in the clinical trials COVID-19 vaccines. The purpose this review to synthesise existing literature on relationship between vaccination outcomes.
Язык: Английский
Процитировано
9