Origins of food selectivity in human visual cortex
Trends in Neurosciences,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 1, 2025
Язык: Английский
Individual variation in the functional lateralization of human ventral temporal cortex: Local competition and long-range coupling
Imaging Neuroscience,
Год журнала:
2025,
Номер
3
Опубликована: Янв. 1, 2025
The
ventral
temporal
cortex
(VTC)
of
the
human
cerebrum
is
critically
engaged
in
high-level
vision.
One
intriguing
aspect
this
region
its
functional
lateralization,
with
neural
responses
to
words
being
stronger
left
hemisphere,
and
faces
right
hemisphere;
such
patterns
can
be
summarized
a
signed
laterality
index
(LI),
positive
for
leftward
laterality.
Converging
evidence
has
suggested
that
word
emerges
couple
efficiently
left-lateralized
frontotemporal
language
regions,
but
more
mixed
regarding
sources
lateralization
face
perception.
Here,
we
use
individual
differences
as
tool
test
three
theories
VTC
organization
arising
from
(1)
local
competition
between
driven
by
long-range
coupling
processes,
(2)
other
categories,
(3)
areas
exhibiting
social
processing.
First,
an
in-house
MRI
experiment,
did
not
obtain
negative
correlation
LIs
selectivity
relative
object
responses,
find
when
using
fixation
baseline,
challenging
ideas
driving
rightward
lateralization.
We
next
examined
broader
LI
interactions
large-scale
Human
Connectome
Project
(HCP)
dataset.
Face
were
significantly
anti-correlated,
while
body
positively
correlated,
consistent
idea
generic
representational
cooperation
may
shape
Last,
assessed
role
development
Within
our
substantial
was
evident
text
several
nodes
distributed
text-processing
circuit.
In
HCP
data,
both
negatively
correlated
processing
different
subregions
posterior
lobe
(PSL
STSp,
respectively).
summary,
no
face-word
VTC;
instead,
multiple
lateralities
within
VTC,
including
Moreover,
also
influenced
lobe,
where
become
lateralized
due
language.
Язык: Английский
The ‘reading’ brain: Meta-analytic insight into functional activation during reading in adults
Neuroscience & Biobehavioral Reviews,
Год журнала:
2025,
Номер
unknown, С. 106166 - 106166
Опубликована: Апрель 1, 2025
Literacy
provides
the
key
to
social
contacts,
education,
and
employment,
significantly
influences
well-being
mental
health.
Summarizing
163
studies,
present
coordinate-based
meta-analysis
confirms
importance
of
classical
left-hemispheric
language
regions
cerebellum
across
reading
tasks.
We
found
high
processing
specificity
for
letter,
word,
sentence,
text
exclusively
in
areas.
Subregions
within
left
inferior
frontal
gyrus
showed
differential
engagement
word
pseudoword
reading,
while
subregions
temporo-occipital
cortex
words
sentences.
The
direct
comparison
overt
covert
revealed
higher
activation
likelihood
auditory
motor
during
first,
more
consistent
reliance
on
multiple
demand
latter.
Last,
silent
(explicit
reading)
yielded
orbito-frontal,
cerebellar
temporal
cortices
when
compared
lexical
decisions
(implicit
reading).
Lexical
decisions,
contrast,
bilateral
recruitment
insular
regions.
extends
our
understanding
neural
architecture
underlying
processes,
corroborates
findings
from
neurostimulation
studies
can
provide
valuable
insight
into
models.
Язык: Английский
Individual variation in the functional lateralization of human ventral temporal cortex: Local competition and long-range coupling
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 16, 2024
Abstract
The
ventral
temporal
cortex
(VTC)
of
the
human
cerebrum
is
critically
engaged
in
computations
related
to
high-level
vision.
One
intriguing
aspect
this
region
its
asymmetric
organization
and
functional
lateralization.
Notably,
VTC,
neural
responses
words
are
stronger
left
hemisphere,
whereas
faces
right
hemisphere.
Converging
evidence
has
suggested
that
left-lateralized
word
emerge
couple
efficiently
with
frontotemporal
language
regions,
but
more
mixed
regarding
sources
right-lateralization
for
face
perception.
Here,
we
use
individual
differences
as
a
tool
adjudicate
between
three
theories
VTC
arising
from:
1)
local
competition
faces,
2)
other
categories,
3)
long-range
coupling
areas
subject
their
own
competition.
First,
an
in-house
MRI
experiment,
demonstrated
laterality
both
substantial
reliable
within
right-handed
population
young
adults.
We
found
no
(anti-)correlation
selectivity
relative
object
responses,
positive
correlation
when
using
fixation
baseline,
challenging
ideas
faces.
next
examined
broader
large-scale
Human
Connectome
Project
(HCP)
dataset.
Face
were
significantly
anti-correlated,
while
body
positively
correlated,
consistent
idea
generic
representational
cooperation
may
shape
Last,
assessed
role
development
laterality.
Within
our
was
evident
text
several
nodes
distributed
text-processing
circuit.
In
HCP
data,
negatively
correlated
laterality,
social
perception
same
areas,
effect
processing
representations,
driven
by
processing.
conclude
interactions
heterogeneous
hemispheric
specializations
visual
cortex.
Язык: Английский
Demystifying the Visual Word Form Area: Visual and Nonvisual Response Properties of Ventral Temporal Cortex with precision fMRI
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Июнь 15, 2023
Summary
The
functional
nature
of
the
visual
word
form
area
(VWFA),
a
region
in
left
ventrotemporal
cortex
(VTC),
remains
debated
after
over
two
decades
investigation.
Here
we
use
precision
fMRI
to
comprehensively
examine
VWFA’s
responses
numerous
and
nonvisual
stimuli.
We
find
that
VWFA
is
distinct
while
showing
moderate
activation
non-word
stimuli,
its
response
words
towers
above
other
conditions.
Interestingly,
also
only
VTC
uniquely
engaged
auditory
language
processing,
contrast
with
ubiquitous
attentional
effect
within
VTC.
However,
this
selectivity
dwarfed
by
responses.
This
suggests
primarily
functions
as
look-up
orthographic
dictionary.
Searching
entire
further
reveals
an
additional
cluster
anterior
fusiform
preferring
general
semantics.
Our
detailed
examination
direct
comparison
regions
clarifies
long-standing
controversies
about
functionality.
Язык: Английский
Music literacy shapes the specialization of a right hemispheric word reading area
Neuroimage Reports,
Год журнала:
2024,
Номер
4(4), С. 100219 - 100219
Опубликована: Сен. 25, 2024
Язык: Английский
Demystifying Visual Word Form Area Visual and Nonvisual Response Properties with Precision fMRI
iScience,
Год журнала:
2024,
Номер
27(12), С. 111481 - 111481
Опубликована: Ноя. 26, 2024
Язык: Английский
Cross-sectional and longitudinal changes in category-selectivity in visual cortex following pediatric cortical resection
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 12, 2024
Abstract
The
topographic
organization
of
category-selective
responses
in
human
ventral
occipitotemporal
cortex
(VOTC)
and
its
relationship
to
regions
subserving
language
functions
is
remarkably
uniform
across
individuals.
This
arrangement
thought
result
from
the
clustering
neurons
responding
similar
inputs,
constrained
by
intrinsic
architecture
tuned
experience.
We
examined
malleability
this
individuals
with
unilateral
resection
VOTC
during
childhood
for
management
drug-resistant
epilepsy.
In
cross-sectional
longitudinal
functional
imaging
studies,
we
compared
topography
neural
representations
17
a
resection,
‘control
patient’
outside
VOTC,
typically
developing
matched
controls.
demonstrated
both
adherence
deviation
standard
uncovered
fine-grained
competitive
dynamics
between
word-
face-selectivity
over
time
single,
preserved
VOTC.
findings
elucidate
nature
extent
cortical
plasticity
highlight
potential
remodeling
extrastriate
function.
Teaser
After
pediatric
deviations
constraints
visual
reflect
plasticity.
Язык: Английский