Behavioural Brain Research, Год журнала: 2024, Номер 476, С. 115281 - 115281
Опубликована: Окт. 5, 2024
Язык: Английский
Behavioural Brain Research, Год журнала: 2024, Номер 476, С. 115281 - 115281
Опубликована: Окт. 5, 2024
Язык: Английский
Brain stimulation, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0Neurogastroenterology & Motility, Год журнала: 2025, Номер unknown
Опубликована: Янв. 6, 2025
Gastric dysmotility and gastric slow wave dysrhythmias have been well documented in patients with diabetes. However, little is known on the effect of hyperglycemia small intestine motility, such as intestinal waves, due to limited options measuring its activity. Moreover, food intake digestion process reported alter motility normal rats, but their roles that diabetic rats remains unknown. This study aimed explore myoelectrical activity (IMA) responses various meals rats. IMA was recorded via chronically implanted serosal electrodes proximal type 2 diabetes induced by high-fat diet feeding followed a low dose streptozotocin (30 mg/kg) The percentage (%NSW), dominant power, frequency (DF) were assessed from under conditions. Oral glucose tolerance test performed, blood collected tail vein at baseline 15, 30, 60, 90, 120, 180 min after administration for measurement glucose. Regular laboratory chow, diet, or large nutrient liquid meal used different (1) Compared postprandial increase DF (p = 0.007), showed blunted response 0.145) regular chow. no difference found %NSW between both fasting fed states; (2) In state, correlated level (r -0.817, p 0.004, N 8) HbA1C -0.871, 0.005, 8). After administration, decrease -0.655, < 0.001, (3) during 30-min state not altered meal, either solid, suggesting an absence gastric-small reflex. regularity waves negatively states. Diabetic exhibit compared There seems be lack reflex upon ingestion
Язык: Английский
Процитировано
0Brain stimulation, Год журнала: 2024, Номер 17(5), С. 987 - 1000
Опубликована: Авг. 23, 2024
Vagus nerve stimulation (VNS) is clinically useful for treating epilepsy, depression, and chronic pain. Currently, cervical VNS (cVNS) treatment well-established, while auricular (aVNS) under development. Vagal regulates functions in diverse brain regions; therefore, it critical to better understand how electrically-evoked vagal inputs following cVNS aVNS engage with different regions.
Язык: Английский
Процитировано
1Behavioural Brain Research, Год журнала: 2024, Номер 476, С. 115281 - 115281
Опубликована: Окт. 5, 2024
Язык: Английский
Процитировано
0