NLRP3 inflammasome in cardiovascular diseases: an update

Frontiers in Immunology, Год журнала: 2025, Номер 16

Опубликована: Фев. 26, 2025

Cardiovascular disease (CVD) continues to be the leading cause of mortality worldwide. The nucleotide oligomerization domain-, leucine-rich repeat-, and pyrin domain-containing protein 3 (NLRP3) inflammasome is involved in numerous types CVD. As part innate immunity, NLRP3 plays a vital role, requiring priming activation signals trigger inflammation. leads both release IL-1 family cytokines distinct form programmed cell death called pyroptosis. Inflammation related CVD has been extensively investigated relation inflammasome. In this review, we describe pathways triggering discuss its pathogenic effects on This study also provides an overview potential therapeutic approaches targeting

Язык: Английский

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Environmental Metal Exposure and Cardiovascular Disease Risk

Journal of the American College of Cardiology, Год журнала: 2025, Номер 85(10), С. e109 - e109

Опубликована: Март 1, 2025

Язык: Английский

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Reply

Journal of the American College of Cardiology, Год журнала: 2025, Номер 85(10), С. e111 - e111

Опубликована: Март 1, 2025

Язык: Английский

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Urinary Metal Levels and Coronary Artery Calcification

Journal of the American College of Cardiology, Год журнала: 2025, Номер 85(10), С. e107 - e107

Опубликована: Март 1, 2025

Язык: Английский

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Metals and Cardiovascular Disease

Elsevier eBooks, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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The role of tungsten in modulating DNA double-Strand break repair and class switch recombination

Toxicology and Applied Pharmacology, Год журнала: 2025, Номер unknown, С. 117392 - 117392

Опубликована: Май 1, 2025

Язык: Английский

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