Global burden of depression or depressive symptoms in children and adolescents: A systematic review and meta-analysis

Journal of Affective Disorders, Год журнала: 2024, Номер 354, С. 553 - 562

Опубликована: Март 14, 2024

Язык: Английский

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Neurobiology and systems biology of stress resilience

Physiological Reviews, Год журнала: 2024, Номер 104(3), С. 1205 - 1263

Опубликована: Март 14, 2024

Stress resilience is the phenomenon that some people maintain their mental health despite exposure to adversity or show only temporary impairments followed by quick recovery. Resilience research attempts unravel factors and mechanisms make possible harness its insights for development of preventative interventions in individuals at risk acquiring stress-related dysfunctions. Biological has been lagging behind psychological social sciences but seen a massive surge recent years. At same time, progress this field hampered methodological challenges related finding suitable operationalizations study designs, replicating findings, modeling animals. We embed review behavioral, neuroimaging, neurobiological, systems biological findings adults critical methods discussion. find preliminary evidence hippocampus-based pattern separation prefrontal-based cognitive control functions protect against pathological fears aftermath singular, event-type stressors [as found fear-related disorders, including simpler forms posttraumatic stress disorder (PTSD)] facilitating perception safety. Reward system-based pursuit savoring positive reinforcers appear more generalized dysfunctions anxious-depressive spectrum resulting from severe longer-lasting (as depression, comorbid anxiety, PTSD). Links between preserved functioning these neural under neuroplasticity, immunoregulation, gut microbiome composition, integrity barrier blood-brain are beginning emerge. On basis, avenues pointed out.

Язык: Английский

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Effect of exercise intervention on depression in children and adolescents: a systematic review and network meta-analysis

BMC Public Health, Год журнала: 2023, Номер 23(1)

Опубликована: Окт. 4, 2023

Abstract Objectives To evaluate the effect of different exercise interventions on depressive symptoms in children and adolescents. Methods Randomized controlled trials (RCT) published until May 2023 were screened four databases. The Cochrane collaboration tool was used to assess risk bias for quality evaluation. Stata 16.0 software both a pairwise meta-analysis series frequentist network meta-analyses (NMA). Results A total 35 RCTs 5393 participants included. Aerobic had most significant (66.2%), followed by group training (62.5%), resistance (59.0%), aerobic combined with (57.9%). Furthermore, adolescents younger than 15 years showed improvement (SMD=-0.41, 95% CI (-0.63, -0.19), P < 0.01). study also found depression among healthy, obesity, depressed populations (SMD=-0.25, (-0.41, -0.08), 0.01); SMD=-0.15, (-0.31, -0.00), 0.01; SMD=-0.75, (-1.32, Additionally, 30 min (SMD=-0.14, (-0,81, -0.01), 0.01), 40–50 best (SMD=-0.17, (-0,33, -0.02), Lastly, frequency three times per week (SMD=-0.42, (-0,66, -0.18), Conclusion Exercise significantly improves adolescents, having effect. 12-week, three-times-a-week, 40-50-minute intervention be more effective

Язык: Английский

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Machine learning meta-analysis identifies individual characteristics moderating cognitive intervention efficacy for anxiety and depression symptoms

npj Digital Medicine, Год журнала: 2025, Номер 8(1)

Опубликована: Янв. 28, 2025

Язык: Английский

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Effects of virtual reality-based cognitive training for adolescents with depressive episodes: A pilot randomized controlled study

Psychiatry Research, Год журнала: 2024, Номер 340, С. 116144 - 116144

Опубликована: Авг. 12, 2024

Язык: Английский

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Evaluating the effect of action-like video game play and of casual video game play on anxiety in adolescents with elevated anxiety: protocol for a multi-center, parallel group, assessor-blind, randomized controlled trial

BMC Psychiatry, Год журнала: 2024, Номер 24(1)

Опубликована: Янв. 19, 2024

Abstract Background Adolescence is a critical period for the onset and maintenance of anxiety disorders, which raises importance intervening early; one possibility doing so via digital interventions. Within that research field, at least two important paths have been explored in past years. On hand, anxiolytic effect casual video games has tested as such gaming activity may distract away from anxious thoughts through induction flow redirection attention toward game thus thoughts. other bidirectional link between weak attentional control higher led to design interventions aiming improving working memory training studies. Taking stock another genre gaming, action games, improves control, game-based combines cognitive action-like features would seem relevant. This three-arm randomized controlled trial aims evaluate feasibility efficacy document how each potentially alleviate adolescent anxiety-related symptoms when deployed fully on-line. Methods The study recruit 150 individuals, 12 14 years age, with high levels reported by parents’ online form Screen Child Anxiety Related Disorders questionnaire. contrasts child-friendly, “action-like” designed improve abilities progressive stepwise manner (Eco-Rescue), puzzle selected act positive distraction tool (Bejeweled) finally group no assigned intervention possible test-retest effects (No-training). Participants will be randomly three arms. They assessed main (anxiety) secondary outcomes (attentional affective memory) time points, before (T1), week after 6-week (T2) four months completing (T3). Discussion results provide evidence mental health emotional well-being adolescents anxiety. project contribute unique knowledge few studies examined play context adolescents. Trial registration registered on ClinicalTrials.gov (NCT05923944, June 20, 2023).

Язык: Английский

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Improving Emotion Regulation, Internalizing Symptoms and Cognitive Functions in Adolescents at Risk of Executive Dysfunction—A Controlled Pilot VR Study

Applied Sciences, Год журнала: 2025, Номер 15(3), С. 1223 - 1223

Опубликована: Янв. 25, 2025

Executive functions (EFs) are essential cognitive processes involved in concentration, planning, decision-making, and impulse control during adolescence. Dysfunction (ED) can lead to significant academic socio-emotional difficulties, particularly with impairments emotion regulation (ER). This study aims assess a virtual reality (VR) training intervention on EFs, ER, internalizing symptoms adolescents at risk for ED. Thirty-eight aged 12–14 years, identified as being moderate high ED, were randomly assigned two groups. The experimental group (n = 22) received gamified VR training, while the 16) nature-based relaxation training. Both interventions lasted five weeks, twice week 30 min each. Pre- post-assessments included ER skills, symptoms, performance measures. Two-way mixed ANOVAs showed × time interactions (p < 0.05) measures of depression symptoms. reductions these compared group. Significant main effects also found some groups experienced reduced anxiety, improved emotional functioning, was effective reducing both promising results improving skills performance. findings demonstrate preliminary VR-based psychological well-being ED suggest that integrating technologies into educational settings effectively address challenges faced by students.

Язык: Английский

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Investigating the effects of a novel gamified cognitive training on adolescent mental health

Research Square (Research Square), Год журнала: 2025, Номер unknown

Опубликована: Фев. 3, 2025

Background Adolescence is a time of increased emotional volatility, with emotion regulation still developing. Training the cognitive substrate successful has been shown to benefit adolescents’ mental health. However, training interventions often have low adherence rates in this age group. The current study therefore trialled novel gamified program adolescents. Methods A longitudinal was conducted throughout 2023 where 144 culturally diverse adolescents (13–16 years, 48% female) completed 12 days either affective control program, Social Brain Train (SBT), or standard non-gamified (AffeCT). Participants also health and mechanisms change questionnaires at baseline, post-training, 1-month follow-up, as well behavioural interpretation bias measures baseline post-training. Results total minutes spent did not differ significantly across two groups. assigned SBT training, however, engage more sessions than participants AffeCT training. Additionally, all showed improvements performance reduction rumination from observed persisted follow-up. Conclusions As engagement most difficult thing achieve adolescents, observing greater repeated promising, given on these apps entirely self-motivated. Observing benefits reduced tendencies after very limited factors previously linked improved symptoms among present findings suggest there may be merit using gamification techniques improve design future programs, employing affective, cognitive, abilities

Язык: Английский

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The differential impact of processing speed and cognitive flexibility on cognitive emotion regulation strategies and depression

Journal of Affective Disorders, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

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Exercise intervention and improvement of negative emotions in children: a meta-analysis

BMC Pediatrics, Год журнала: 2023, Номер 23(1)

Опубликована: Авг. 22, 2023

Abstract Background Anxiety, depression, and stress are the most common mental health problems in childhood. Exercise interventions childhood help to promote health. Objective To investigate relationship between exercise improvement of negative emotions such as anxiety, children (5–12 years). Methods Articles were searched five electronic databases from their inception January 2023. The meta-analysis was performed using Stata 16.0. Results Twenty-three intervention studies included 6830 children. 1) group significantly better than control improving (Standard Mean Difference SMD=-0.25, 95% Confidence Intervals CI: -0.34 -0.15, P < 0.01). improved different kinds emotions: anxiety (SMD=-0.19, -0.33 -0.06, 0.01), depression (SMD=-0.22, -0.43 -0.01, (SMD=-0.33, -0.53 -0.14, 0.01); it effective at relieving problematic stress. lasting 20–45 min children’s (SMD=-0.38, -0.56 -0.20, An period 10 weeks more mood (SMD=-0.26, -0.17, = 0.274). Conclusion may improve These findings have clinical implications for with affect. However, these showed a large heterogeneity, results should be interpreted caution. Future report variability by gender, age group, type, intensity, place exercise.

Язык: Английский

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