The Canadian Journal of Psychiatry,
Год журнала:
2024,
Номер
69(7), С. 503 - 512
Опубликована: Фев. 28, 2024
Objective
Medications
are
critical
for
treating
major
depressive
disorder
(MDD)
and
bipolar
(BD).
Unfortunately,
30%
to
40%
of
individuals
do
not
respond
well
current
pharmacotherapy.
Given
the
compelling
growing
body
research
on
gut-brain
axis,
this
study
aims
assess
patient
perspectives
regarding
microbiome-based
therapies
(MBT)
such
as
probiotics,
prebiotics,
dietary
changes,
or
fecal
microbiota
transplantation
(FMT)
in
management
MDD
BD.
Methods
This
single-centred
observational
used
quantitative
qualitative
assessments
examine
perceptions
MBT.
Participants
diagnosed
with
BD
completed
an
anonymous
questionnaire
obtaining
demographics,
prior
medication
history,
symptom
burden.
Self-assessment
questionnaires
specific
each
diagnosis
were
also
used:
Quick
Inventory
Depressive
Symptomatology
Self-Report
(QIDS-SR),
Altman
Self-Rating
Mania
Scale
(ASRM),
General
Anxiety
Disorder
Questionnaire
(GAD-7).
A
logistic
regression
model
analysed
association
MBT
acceptance
type,
QIDS-SR,
GAD-7
scores.
bootstrap
method
assessed
proportion
acceptance.
The
assessment
consisted
30-minute
interviews
elicit
attitudes
towards
Results
achieved
information
power
n
=
20.
from
63-item
(
43)
showed
probiotics
(37.2%)
top
choice,
followed
by
FMT
(32.6%),
change
(25.6%),
prebiotics
(4.6%).
majority
participants
(72.1%)
expressed
willingness
try
their
mood
disorder,
however,
analysis
did
identify
statistically
significant
predictors
among
GAD-7.
Conclusion
There
is
increased
focus
gut
microbiota's
role
disorders’
etiology
treatment.
Promising
interest
underscore
necessity
exploring
educating
factors
influencing
Health Science Reports,
Год журнала:
2023,
Номер
6(10)
Опубликована: Окт. 1, 2023
Abstract
Background
Depression
affects
personal
and
public
well‐being
identification
of
natural
therapeutics
such
as
nutrition
is
necessary
to
help
alleviate
this
health
concern.
Objective
The
study
aimed
identify
feature
importance
in
a
machine
learning
model
using
solely
covariates.
Methods
A
retrospective
analysis
was
conducted
modern,
nationally
representative
cohort,
the
National
Health
Nutrition
Examination
Surveys
(NHANES
2017−2020).
Depressive
symptoms
were
evaluated
validated
9‐item
Patient
Questionnaire
(PHQ‐9),
all
adult
patients
(total
7929
individuals)
who
completed
PHQ‐9
total
nutritional
intake
questionnaire
included
study.
Univariable
regression
used
significant
covariates
be
reported.
acquisition
data
authorized
by
Center
for
Statistics
Ethics
Review
Board.
Results
met
inclusion
criteria
had
24
out
60
features
that
found
on
univariate
(
p
<
0.01
used).
In
XGBoost
an
Area
Under
Receiver
Operator
Characteristic
Curve
(AUROC)
=
0.603,
Sensitivity
0.943,
Specificity
0.163.
top
four
highest
ranked
gain,
measure
percentage
contribution
covariate
overall
prediction,
Potassium
Intake
(Gain
6.8%),
Vitamin
E
5.7%),
Number
Foods
Beverages
Reported
K
5.6%).
Conclusion
Machine
models
with
can
utilized
further
clinical
depression.
Cadernos de Saúde Pública,
Год журнала:
2023,
Номер
39(10)
Опубликована: Янв. 1, 2023
Abstract:
This
study
aims
to
determine
the
association
of
adherence
Mediterranean
diet
and
its
food
groups
with
depressive
symptoms
in
Chilean
university
students.
The
design
was
cross-sectional.
A
total
934
first-year
students
at
a
public
completed
self-report
questionnaire.
To
assess
diet,
an
index
validated
Chile
(Chilean-MDI)
used,
depression,
anxiety,
stress
were
assessed
using
Depression
Anxiety
Stress
Scale
(DASS-21).
Logistic
regression
models
used
analyze
adjusted
for
main
confounders.
Students
moderate
high
showed
lower
odds
depression
[DASS-21
>
5,
ratio
(OR)
=
0.64;
95%
confidence
interval
(95%CI):
0.47-0.88]
than
those
low
diet.
consumption
1-2
servings/day
vegetables
(OR
0.63;
95%CI:
0.43-0.92),
2
servings/week
nuts
0.41;
0.21-0.80),
fruits
0.60;
0.42-0.85),
fish
seafood
0.67;
0.48-0.94),
1/2-3
units/week
avocado
0.48-0.93)
symptoms.
whole
grains
cereals
(>
servings/day)
1.63;
1.02-2.61)
opposite
association.
Adherence
fruits,
vegetables,
nuts,
avocado,
fish,
are
associated
likelihood
New
policies
educational
strategies
recommended
improve
quality
mental
health
entire
community.
European Psychiatry,
Год журнала:
2024,
Номер
67(1)
Опубликована: Янв. 1, 2024
Abstract
There
is
growing
interest
in
lifestyle
interventions
as
stand-alone
and
add-on
therapies
mental
health
care
due
to
their
potential
benefits
for
both
physical
outcomes.
We
evaluated
focusing
on
activity,
diet,
sleep
adults
with
severe
illness
(SMI)
the
evidence
effectiveness.
To
this
end,
we
conducted
a
meta-review
searched
major
electronic
databases
articles
published
prior
09/2022
updated
our
search
03/2024.
identified
89
relevant
systematic
reviews
assessed
quality
using
SIGN
checklist.
Based
findings
of
clinical
expertise
authors,
formulated
seven
recommendations.
In
brief,
supports
application
that
combine
behavioural
change
techniques,
dietary
modification,
activity
reduce
weight
improve
cardiovascular
parameters
SMI.
Furthermore,
should
be
used
an
adjunct
treatment
SMI,
including
psychotic
symptoms
cognition
schizophrenia
or
depressive
depression.
ameliorate
quality,
cognitive
informed
can
considered.
Additionally,
provide
overview
key
gaps
current
literature.
Future
studies
integrate
outcomes
reflect
multi-faceted
interventions.
Moreover,
highlighted
relative
dearth
relating
bipolar
disorder
nutritional
research
could
help
establish
core
component
care.
The Canadian Journal of Psychiatry,
Год журнала:
2024,
Номер
69(7), С. 503 - 512
Опубликована: Фев. 28, 2024
Objective
Medications
are
critical
for
treating
major
depressive
disorder
(MDD)
and
bipolar
(BD).
Unfortunately,
30%
to
40%
of
individuals
do
not
respond
well
current
pharmacotherapy.
Given
the
compelling
growing
body
research
on
gut-brain
axis,
this
study
aims
assess
patient
perspectives
regarding
microbiome-based
therapies
(MBT)
such
as
probiotics,
prebiotics,
dietary
changes,
or
fecal
microbiota
transplantation
(FMT)
in
management
MDD
BD.
Methods
This
single-centred
observational
used
quantitative
qualitative
assessments
examine
perceptions
MBT.
Participants
diagnosed
with
BD
completed
an
anonymous
questionnaire
obtaining
demographics,
prior
medication
history,
symptom
burden.
Self-assessment
questionnaires
specific
each
diagnosis
were
also
used:
Quick
Inventory
Depressive
Symptomatology
Self-Report
(QIDS-SR),
Altman
Self-Rating
Mania
Scale
(ASRM),
General
Anxiety
Disorder
Questionnaire
(GAD-7).
A
logistic
regression
model
analysed
association
MBT
acceptance
type,
QIDS-SR,
GAD-7
scores.
bootstrap
method
assessed
proportion
acceptance.
The
assessment
consisted
30-minute
interviews
elicit
attitudes
towards
Results
achieved
information
power
n
=
20.
from
63-item
(
43)
showed
probiotics
(37.2%)
top
choice,
followed
by
FMT
(32.6%),
change
(25.6%),
prebiotics
(4.6%).
majority
participants
(72.1%)
expressed
willingness
try
their
mood
disorder,
however,
analysis
did
identify
statistically
significant
predictors
among
GAD-7.
Conclusion
There
is
increased
focus
gut
microbiota's
role
disorders’
etiology
treatment.
Promising
interest
underscore
necessity
exploring
educating
factors
influencing
