Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 625 - 655
Опубликована: Янв. 1, 2025
Язык: Английский
Journal of Personalized Medicine, Год журнала: 2024, Номер 14(2), С. 217 - 217
Опубликована: Фев. 18, 2024
Infectious diseases have long posed a significant threat to global health and require constant innovation in treatment approaches. However, recent groundbreaking research has shed light on previously overlooked player the pathogenesis of disease-the human microbiome. This review article addresses intricate relationship between microbiome infectious unravels its role as crucial mediator host-pathogen interactions. We explore remarkable potential harnessing this dynamic ecosystem develop innovative strategies that could revolutionize management diseases. By exploring latest advances emerging trends, aims provide new perspective combating by targeting
Язык: Английский
Процитировано
22
Frontiers in Microbiology, Год журнала: 2023, Номер 14
Опубликована: Дек. 19, 2023
Postbiotics, which are bioactive substances derived from the metabolic processes of beneficial microbes, have received considerable attention in field microbiome science recent years, presenting a promising path for exploration and innovation. This comprehensive analysis looks into multidimensional terrain postbiotic production, including an extensive examination diverse classes, revealing their sophisticated mechanisms action highlighting future applications that might significantly affect human health. The authors thoroughly investigate various support ranging conventional fermentation procedures to cutting-edge enzyme conversion synthetic biology approaches. review, as acknowledgment field’s developing nature, not only highlights current achievements but also navigates through problems inherent production. In order successfully include postbiotics therapeutic interventions production functional food ingredients, emphasis is given critical elements, improving yields, bolstering stability, assuring safety. knowledge presented herein sheds light on expanding potential revolutionize development novel therapeutics ingredients.
Язык: Английский
Процитировано
32
Microorganisms, Год журнала: 2024, Номер 12(1), С. 194 - 194
Опубликована: Янв. 18, 2024
Probiotics are known to promote human health either precautionary in healthy individuals or therapeutically patients suffering from certain ailments. Although this knowledge was empirical past tomes, modern science has already verified it and expanded new limits. These microorganisms can be found nature various foods such as dairy products supplements formulated for clinical preventive use. The current review examines the different mechanisms of action probiotic strains how they interact with organism host. Emphasis is put on therapeutic use these beneficial conditions gastrointestinal tract. Diseases tract particularly any malfunction inflammation intestines seriously compromise whole organism. interaction between host’s microbiota alleviate signs symptoms while some cases, due course, intervene underlying pathology. Various safety issues probiotics also discussed.
Язык: Английский
Процитировано
13
International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(10), С. 5441 - 5441
Опубликована: Май 16, 2024
This review highlights the role of postbiotics, which may provide an underappreciated avenue doe promising therapeutic alternatives. The discovery natural compounds obtained from microorganisms needs to be investigated in future terms their effects on various metabolic disorders and molecular pathways, as well modulation immune system intestinal microbiota children adults. However, further studies efforts are needed evaluate describe new postbiotics. provides available knowledge that assist research identifying postbiotics uncovering additional mechanisms combat diseases.
Язык: Английский
Процитировано
13
Journal of Nutrition and Metabolism, Год журнала: 2024, Номер 2024(1)
Опубликована: Янв. 1, 2024
Food safety is a global concern, with millions suffering from foodborne diseases annually. The World Health Organization (WHO) reports significant morbidity and mortality associated contaminated food consumption, this emphasizes the critical need for comprehensive measures. Recent attention has turned to postbiotics, metabolic byproducts of probiotics, as potential agents enhancing safety. Postbiotics, including organic acids, enzymes, bacteriocins, exhibit antimicrobial antioxidant properties that do not require live organisms, offers advantages over probiotics. This literature review critically examines role postbiotics in gut microbiome modulation applications industry. Through an extensive existing literature, study evaluates impact on composition their functional ingredients. Research indicates are effective inhibiting pathogens such
Язык: Английский
Процитировано
13
Nutrients, Год журнала: 2024, Номер 16(22), С. 3955 - 3955
Опубликована: Ноя. 19, 2024
The trillions of microbes that constitute the human gut microbiome play a crucial role in digestive health, immune response regulation, and psychological wellness. Maintaining microbiota is essential as metabolic diseases are associated with it. Functional food ingredients potentially improving health include prebiotics, probiotics, synbiotics, postbiotics (PPSPs). While probiotics living bacteria provide advantages when ingested sufficiently, prebiotics non-digestible carbohydrates support good bacteria. Synbiotics work together to improve immunity intestinal by combining prebiotics. Postbiotics have also demonstrated numerous advantages, such bioactive molecules created during probiotic fermentation. According recent study, PPSPs can regulate synthesis metabolites, integrity barrier, change composition control illnesses. Additionally, use fecal transplantation (FMT) highlights potential for restoring through modulation, reinforcing benefits enhancing overall well-being. Research has shown several benefits, improved immunological function, alleviation symptoms irritable bowel disease (IBD), decreased severity allergies, antibacterial anti-inflammatory effects. Despite encouraging results, many unanswered questions remain about scope PPSPs' advantages. Extensive research required fully realize these functional components Effective therapeutic prophylactic measures require further investigation into roles PPSPs, specifically their immune-system-modulating, cholesterol-lowering, antioxidant, characteristics.
Язык: Английский
Процитировано
13
Advanced Drug Delivery Reviews, Год журнала: 2024, Номер 210, С. 115332 - 115332
Опубликована: Май 15, 2024
Язык: Английский
Процитировано
9
Allergy, Год журнала: 2024, Номер 79(7), С. 1708 - 1724
Опубликована: Май 23, 2024
Abstract This systematic review and meta‐analysis aimed to consolidate evidence on dietary interventions for atopic eczema/dermatitis (AD) skin symptoms in children without food allergies, following PRISMA 2020 guidelines. Systematic updates were conducted May 2022 June 2023, focusing randomized placebo‐controlled trials (RCTs) involving with AD but allergies. Specific diets or supplements, such as vitamins, minerals, probiotics, prebiotics, symbiotics, postbiotics, explored these trials. Exclusions comprised descriptive studies, reviews, meta‐analyses, letters, case reports, studies elimination diets, those reporting allergens adolescents. Additionally, assessing exacerbation of due allergy/sensitization evaluating diets' effects excluded. Nutritional supplementation eligible regardless sensitization profile. Evaluation their impact clinical expression was performed using SCORAD scores, a outcomes random‐effect models (CRD42022328702). The encompassed 27 RCTs examining Vitamin D, evening primrose oil, substituting cow's milk formula partially hydrolyzed whey formula. A 20 alone combined revealed significant reduction suggesting consistent trend alleviating Nonetheless, other remains limited, underscoring the necessity well‐designed intervention targeting multiple factors understand etiological interactions propose reliable manipulation strategies.
Язык: Английский
Процитировано
9
Foods, Год журнала: 2024, Номер 13(15), С. 2386 - 2386
Опубликована: Июль 28, 2024
Fermented foods can provide many benefits to our health. These are created by the action of microorganisms and help support digestive health immune system. include yogurt,
Язык: Английский
Процитировано
8
Foods, Год журнала: 2024, Номер 13(16), С. 2487 - 2487
Опубликована: Авг. 8, 2024
Microbial contamination of food and alimentary toxoinfection/intoxication in humans are commonly caused by bacteria such as
Язык: Английский
Процитировано
8