Research Square (Research Square),
Год журнала:
2023,
Номер
unknown
Опубликована: Май 19, 2023
Abstract
Objectives:
This
study
examined
the
relationship
between
comorbidity
indices
and
comprehensive
geriatric
assessment
including
psychologic,
social
frailty,
geropsychiatric
evaluation.
Methods:
A
cross-sectional
analysis
was
conducted
with
136
community-dwelling
older
adults.
The
of
4
(CIRS-G,
ACCI,
GIC,
ICED)
3
different
frailty
scales
(FRAIL,
CFS,
TFI)
examined.
Results:
Overall,
58.8%
participants
were
living
according
to
TFI,
47.7%
them
psychological
28.6%
frailty.
There
significant
moderate
correlations
CIRS-G
FRAIL,
CFS
TFI
total
scores,
TFI-Psychological
scores
TFI-Social
(respectively;
p<0.001,
r
=
0.530;
0.471;
0.535;
0.402;
p=
0.016
0.206).
AUC
for
calculated
as
0.746
among
in
predicting
presence
(p<0.001,
95%CI
[0.66-0.82]),
ACCI
0.631
(p=0.01,
[0.53-0.72]),
GIC
0.595
(p=0.059,
[0.49-0.69]),
ICED
0.666
(p=0.001,
[0.57-0.75]).
Conclusion:
index
found
be
superior
other
indices,
only
showed
results
mortality.
However,
it
would
incomplete
conclude
a
alone
by
ignoring
assessment.
Geriatrics and gerontology international/Geriatrics & gerontology international,
Год журнала:
2024,
Номер
24(4), С. 371 - 377
Опубликована: Фев. 23, 2024
Aim
This
cross‐sectional
study
had
two
aims:
to
assess
the
prevalence
of
oral
frailty
(OF),
according
Oral
Frailty
5‐Item
Checklist
(OF‐5),
among
community‐dwelling
older
adults;
and
examine
associations
frailty,
dietary
variety,
social
engagement,
physical
frailty.
Methods
We
pooled
data
from
population‐based
studies
(the
Otassha
Study
Itabashi
Longitudinal
on
Aging).
With
OF‐5,
OF
is
characterized
by
presence
or
more
following:
(i)
fewer
teeth,
(ii)
difficulty
in
chewing,
(iii)
swallowing,
(iv)
dry
mouth,
(v)
low
articulatory
motor
skills.
calculated
for
each
sex.
assessed
Generalized
structural
equation
modeling
was
employed
investigate
variety
(dietary
score
≤3),
isolation
(Lubben
Social
Network
Scale
<12),
(Japanese
version
Cardiovascular
Health
≥3).
Results
A
total
1206
individuals
(626
women
580
men)
with
a
mean
age
74.7
years
were
included.
The
36.7%,
it
increased
age;
however,
there
no
significant
sex
difference.
significantly
indirectly
associated
via
(odds
ratio,
1.43;
95%
confidence
interval,
1.04–1.97)
1.42;
1.04–1.94).
Conclusions
Two
five
adults
exhibited
OF.
Low
are
potential
underlying
mechanisms
through
which
Geriatr
Gerontol
Int
2024;
24:
371–377
.
PLoS ONE,
Год журнала:
2024,
Номер
19(2), С. e0297837 - e0297837
Опубликована: Фев. 26, 2024
Social
isolation
exacerbates
physical
frailty
and
is
associated
with
subjective
well-being.
Even
those
high
levels
of
social
may
have
different
health
statuses
depending
on
the
type
their
However,
effect
well-being
relationship
between
remains
unclear.
This
study
examined
whether
risk
was
same
for
individuals
according
to
low
The
participants
included
1,953
middle-aged
Japanese
adults
aged
45
years
older.
Physical
assessed
using
a
modified
version
Fried
phenotype
criteria.
Probabilistic
Latent
Semantic
Analysis
used
classify
indicators.
Subsequently,
we
focused
groups
classified
them
or
low.
Subjective
evaluated
Shiawase
Ikigai
scales,
which
are
concepts
in
Japan.
Finally,
survival
time
analysis
examine
isolation.
were
into
four
based
status.
rate
class
37.0%,
significantly
higher
than
that
other
classes.
Survival
revealed
among
people
isolation,
had
lower
.
All
not
at
frailty.
findings
reveal
even
level
if
high.
These
results
will
contribute
promoting
prevention
older
adults.
It
is
unclear
whether
social
isolation
and
loneliness
may
precede
frailty
status
or
precipitate
loneliness.
We
investigated
the
reciprocal
temporal
sequence
of
isolation,
loneliness,
among
older
adults
across
21
years.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Март 27, 2024
Frailty,
social
isolation,
and
loneliness
have
individually
been
associated
with
adverse
health
outcomes.
This
study
examines
how
frailty
in
combination
or
isolation
is
socioeconomic
deprivation
all-cause
mortality
hospitalisation
rate
a
middle-aged
older
population.
Baseline
data
from
461,047
UK
Biobank
participants
(aged
37-73)
were
used
to
assess
(frailty
phenotype),
loneliness.
Weibull
models
assessed
the
association
between
adjusted
for
age/sex/smoking/alcohol/socioeconomic-status
number
of
long-term
conditions.
Negative
binomial
regression
rate.
Frailty
prevalence
was
3.38%,
4.75%
9.04%.
present
across
all
ages
increased
age.
Loneliness
more
common
younger
compared
older.
Co-occurrence
most
high
deprivation.
regardless
isolation/loneliness.
Hazard
ratios
2.47
(2.27-2.69)
2.17
(2.05-2.29)
without
2.14
(1.92-2.38)
2.16
(2.05-2.27)
robust
participants,
but
this
attenuated
context
frailty.
loneliness/social
affect
individuals
wide
age
spectrum
disproportionately
co-occur
areas
All
outcomes,
outcomes
Future
interventions
should
target
people
living
Journal of General Internal Medicine,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 22, 2025
Abstract
Background
The
importance
of
integrating
physical
and
psychosocial
factors
in
assessing
frailty
-health
outcomes
has
been
increasingly
acknowledged,
while
the
related
evidence
is
lacking.
We
sought
to
investigate
associations
joint
physical-psychosocial
with
risk
premature
mortality
evaluate
relative
individual
factors.
Design
A
total
381,295
participants
no
history
cancer
or
cardiovascular
disease
(CVD)
were
recruited
from
UK
Biobank
cohort.
was
evaluated
based
on
seven
indicators
including
weight
loss,
exhaustion,
activity,
walking
pace,
grip
strength,
social
isolation,
loneliness.
all
causes,
cancer,
CVD,
other
causes.
Cox
proportional
hazards
models
used
assess
between
mortality.
Key
Results
During
a
median
follow-up
period
12.7
years,
we
recorded
20,328
deaths.
Each
additional
increment
index
associated
26%
(HR
1.26,
95%
CI
1.24–1.28),
10%
1.10,
1.08–1.12),
30%
1.30,
1.26–1.33),
44%
1.44,
1.41–1.47)
higher
all-cause,
cardiovascular,
other-cause
mortality,
respectively.
Compared
0,
those
≥
4
had
2.67
(95%
2.49–2.87)-fold
all-cause
Slow
pace
isolation
top
two
strongest
predictors
for
In
addition,
found
that
lower
body
mass
(BMI),
age,
smoking
status,
dietary
quality
modified
(
P
-interaction
<
0.05).
Conclusions
this
cohort
study
participants,
significantly
risks
cause-specific
highlighting
jointly
determining
aging-related
health.
Frailty
and
pre-frailty
are
major
public
health
concerns.
While
frailty
is
typically
associated
with
older
adults,
evidence
suggests
that
commonly
starts
in
middle-age.
This
study
examined
associations
between
behavioural
psychological
correlates
of
adults
from
40
years
to
help
identify
at-risk
individuals
inform
interventions.
Participants
(N
=
321,
mean
age
56
(10.55),
83%
female)
completed
questionnaires
on
status,
physical
activity,
co-morbidities,
quality
life,
loneliness,
social
isolation,
attitudes
towards
ageing.
were
classified
as
non-frail
(35%),
pre-frail
(60%),
or
frail
(5%).
One-way
ANCOVAs,
controlling
for
age,
BMI,
found
participants
reported
feeling
than
their
chronological
(F
2.37,
p
<
.014,
η2
.398);
greater
loneliness
6.31,
.022,
.073)
negative
toward
ageing
2.41,
.004,
.210)
compared
participants.
These
findings
indicate
the
need
targeted
holistic
interventions
middle
prevent
delay
frailty.
highlights
your
actual
can
signal
early
frailty,
even
people
young
40.
align
World
Health
Organisation's
Decade
Healthy
Ageing
initiative,
which
emphasises
importance
fostering
positive
support
healthy
outcomes.
insights
stress
mental
maintaining
connections
successfully.
By
recognising
addressing
these
warning
signs,
communities
healthcare
providers
implement
stay
healthier
longer,
potentially
reducing
costs
improving
life
our
population
ages.
Socially
isolated
older
adults
incur
increased
risks
of
adverse
health
outcomes,
though
the
strength
this
association
is
unclear.
We
examined
whether
changes
in
physical
frailty
moderated
associations
between
social
relationships
and
outcomes
among
adults.
