Origin, evolution, and diversification of the wall-associated kinase gene family in plants

Plant Cell Reports, Год журнала: 2023, Номер 42(12), С. 1891 - 1906

Опубликована: Сен. 25, 2023

Язык: Английский

---

Melatonin alleviates glyphosate-induced testosterone synthesis inhibition via targeting mitochondrial function in roosters

Environmental Pollution, Год журнала: 2024, Номер 348, С. 123828 - 123828

Опубликована: Март 22, 2024

Язык: Английский

---

Selenium alleviates cadmium-induced oxidative stress, endoplasmic reticulum stress and programmed necrosis in chicken testes

The Science of The Total Environment, Год журнала: 2022, Номер 863, С. 160601 - 160601

Опубликована: Дек. 15, 2022

Язык: Английский

---

Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells

Frontiers in Pharmacology, Год журнала: 2022, Номер 13

Опубликована: Авг. 11, 2022

Cadmium (Cd) is a toxic heavy metal extensively used in industrial and agricultural production. Among the main mechanisms of Cd-induced liver damage oxidative stress. Quercetin (QE) natural antioxidant. Herein, protective effect QE on hepatocyte injury was investigated. BRL-3A cells were treated with 12.5 μmol/L CdCl 2 and/or 5 for 24 h. The medium supernatant collected, ALT, AST, LDH contents detected. activities or SOD, CAT, GSH, MDA determined. Intracellular ROS levels examined by flow cytometry. Apoptosis rate mitochondrial-membrane potential (ΔΨm) detected Hoechst 33,258 JC-1 methods, respectively. mRNA protein expression Nrf2, NQO1, Keap1, CytC, caspase-9, caspase-3, Bax, Bcl-2 determined real-time PCR (RT-PCR) Western blot methods. Results showed that Cd exposure injured cells, activity antioxidant enzymes decreased cell level increased, whereas ΔΨm decreased, apoptotic genes increased. inhibited Nrf2-Keap1 pathway, Nrf2 increased Keap1 expression. Through combined action QE, activated pathway. Consequently, antioxidant-enzyme cellular alleviated, apoptosis inhibited. After Cd, NQO1 decreased. Therefore, exerted an activating pathway cells.

Язык: Английский

---

Mechanism of evodiamine blocking Nrf2/MAPK pathway to inhibit apoptosis of grass carp hepatocytes induced by DEHP

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Год журнала: 2022, Номер 263, С. 109506 - 109506

Опубликована: Ноя. 8, 2022

Язык: Английский

---