Mitochondria-targeting therapeutic strategies for chronic kidney disease DOI Creative Commons

Annie Sun,

Carol A. Pollock, Chunling Huang

и другие.

Biochemical Pharmacology, Год журнала: 2024, Номер unknown, С. 116669 - 116669

Опубликована: Ноя. 1, 2024

Язык: Английский

Preparation of a multiple interacting magnetic fluid for rapid and sensitive simultaneous extraction of β-nicotinamide mononucleotide metabolites in biological samples DOI
Yajie Zhang,

Zhuhui Chen,

Aoli Ye

и другие.

Analytica Chimica Acta, Год журнала: 2024, Номер 1325, С. 343074 - 343074

Опубликована: Авг. 15, 2024

Язык: Английский

Процитировано

0
Dissection of Targeting Molecular Mechanisms of Celastrol-induced Nephrotoxicity via A Combined Deconvolution Strategy of Chemoproteomics and Metabolomics DOI Creative Commons
Xueying Liu, Qian Zhang, Peili Wang

и другие.

International Journal of Biological Sciences, Год журнала: 2024, Номер 20(12), С. 4601 - 4617

Опубликована: Янв. 1, 2024

Celastrol (Cel), derived from the traditional herb

Язык: Английский

Процитировано

0
Role of cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes pathway in diabetes and its complications DOI

Mingwei Fan,

Jin-Lan Tian,

Tan Chen

и другие.

World Journal of Diabetes, Год журнала: 2024, Номер 15(10), С. 2041 - 2057

Опубликована: Сен. 26, 2024

Diabetes mellitus (DM) is one of the major causes mortality worldwide, with inflammation being an important factor in its onset and development. This review summarizes specific mechanisms cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS)-stimulator interferon genes (STING) pathway mediating inflammatory responses. Furthermore, it comprehensively presents related research progress subsequent involvement this pathogenesis early-stage DM, diabetic gastroenteropathy, cardiomyopathy, non-alcoholic fatty liver disease, other complications. Additionally, role cGAS-STING autonomic dysfunction intestinal dysregulation, which can lead to digestive complications, has been discussed. Altogether, study provides a comprehensive analysis advances regarding pathway-targeted therapeutic agents prospects for their application precision treatment DM.

Язык: Английский

Процитировано

0
NAD+ enhancers as therapeutic agents in the cardiorenal axis DOI Creative Commons

Mariano Marín-Blázquez,

Jordi Rovira, María José Ramírez-Bajo

и другие.

Cell Communication and Signaling, Год журнала: 2024, Номер 22(1)

Опубликована: Ноя. 8, 2024

Cardiorenal diseases represent a complex interplay between heart failure and renal dysfunction, being clinically classified as cardiorenal syndromes (CRS). Recently, the contributions of altered nicotinamide adenine dinucleotide (NAD

Язык: Английский

Процитировано

0
Mitochondria-targeting therapeutic strategies for chronic kidney disease DOI Creative Commons

Annie Sun,

Carol A. Pollock, Chunling Huang

и другие.

Biochemical Pharmacology, Год журнала: 2024, Номер unknown, С. 116669 - 116669

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

0