Development of a high-performance liquid chromatography analytical method

Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 389 - 510

Опубликована: Янв. 1, 2025

Язык: Английский

Recent Progress in Developing Extracellular Vesicles as Nanovehicles to Deliver Carbohydrate-Based Therapeutics and Vaccines

Vaccines, Год журнала: 2025, Номер 13(3), С. 285 - 285

Опубликована: Март 7, 2025

Cell-derived, nanoscale extracellular vesicles (EVs) have emerged as promising tools in diagnostic, therapeutic, and vaccine applications. Their unique properties including the capability to encapsulate diverse molecular cargo well versatility surface functionalization make them ideal candidates for safe effective vehicles deliver a range of biomolecules gene editing cassettes, therapeutic proteins, glycans, glycoconjugate vaccines. In this review, we discuss recent advances development EVs derived from mammalian bacterial cells use delivery carbohydrate-based protein therapeutics We highlight key innovations EVs’ design, characterization, deployment treating diseases Alzheimer’s disease, infectious diseases, cancers. challenges their clinical translation provide perspectives future within biopharmaceutical research landscape.

Язык: Английский

Unraveling Extracellular Vesicle DNA: Biogenesis, Functions, and Clinical Implications

Pathology - Research and Practice, Год журнала: 2025, Номер unknown, С. 155937 - 155937

Опубликована: Март 1, 2025

Язык: Английский