Development of a high-performance liquid chromatography analytical method

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 389 - 510

Published: Jan. 1, 2025

Language: Английский

Recent Progress in Developing Extracellular Vesicles as Nanovehicles to Deliver Carbohydrate-Based Therapeutics and Vaccines

Vaccines, Journal Year: 2025, Volume and Issue: 13(3), P. 285 - 285

Published: March 7, 2025

Cell-derived, nanoscale extracellular vesicles (EVs) have emerged as promising tools in diagnostic, therapeutic, and vaccine applications. Their unique properties including the capability to encapsulate diverse molecular cargo well versatility surface functionalization make them ideal candidates for safe effective vehicles deliver a range of biomolecules gene editing cassettes, therapeutic proteins, glycans, glycoconjugate vaccines. In this review, we discuss recent advances development EVs derived from mammalian bacterial cells use delivery carbohydrate-based protein therapeutics We highlight key innovations EVs’ design, characterization, deployment treating diseases Alzheimer’s disease, infectious diseases, cancers. challenges their clinical translation provide perspectives future within biopharmaceutical research landscape.

Language: Английский

Unraveling Extracellular Vesicle DNA: Biogenesis, Functions, and Clinical Implications

Pathology - Research and Practice, Journal Year: 2025, Volume and Issue: unknown, P. 155937 - 155937

Published: March 1, 2025

Language: Английский