Dynamic Tracking of Biological Processes Using Near-Infrared Fluorescent Single-Walled Carbon Nanotubes
ACS Applied Materials & Interfaces,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 8, 2024
Biological
processes
are
characterized
by
dynamic
and
elaborate
temporal
patterns
driven
the
interplay
of
genes,
proteins,
cellular
components
that
crucial
for
adaptation
to
changing
environments.
This
complexity
spans
from
molecular
organismal
scales,
necessitating
their
real-time
monitoring
tracking
unravel
active
fuel
living
systems
enable
early
disease
detection,
personalized
medicine,
drug
development.
Single-walled
carbon
nanotubes
(SWCNTs),
with
unique
physicochemical
optical
properties,
have
emerged
as
promising
tools
such
processes.
perspective
highlights
key
properties
SWCNTs
make
them
ideal
monitoring.
Subsequently,
it
surveys
studies
utilizing
track
biological
phenomena
across
hierarchical
levels─from
molecules
cells,
tissues,
organs,
whole
organisms─acknowledging
pivotal
role
in
advancing
this
field.
Finally,
review
outlines
challenges
future
directions,
aiming
expand
frontier
using
SWCNTs,
contributing
deeper
insights
novel
applications
biomedicine.
Язык: Английский
Metal-Ion Optical Fingerprinting Sensor Selection via an Analyte Classification and Feature Selection Algorithm
Analytical Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 27, 2025
Accurate
analyte
classification
remains
a
significant
challenge
in
sensor
technologies.
We
present
the
Analyte
Classification
and
Feature
Selection
Algorithm
(ACFSA),
computational
tool
designed
to
identify
optimal
combinations
from
unique
fingerprint
patterns
for
classification.
applied
ACFSA
library
of
peptide-corona-functionalized
single-walled
carbon
nanotubes
(SWCNTs),
developed
as
near-infrared
fluorescent,
semiselective
fingerprinting
set
detecting
heavy
metal
ions.
Inspired
by
natural
metal-ion
complexation
sites,
each
SWCNT
this
features
peptide
sequence
containing
various
amino
acids
binding,
revealing
diverse
optical
response
ions
tested.
The
was
further
diversified
using
different
chiralities
photochemical
modifications
coronae.
screening
data
fluorescence
30
resulting
SWCNT-peptide
sensors
five
analytes.
Through
iterative
dimensionality
reduction
rational
selection,
algorithm
identified
minimal
two-sensor
with
0.02%
error.
final
output
is
thus
an
classifier
that
serves
pattern
selected
sensors.
peptide-SWCNT
system
effective
proof-of-concept,
illustrating
potential
our
platform
generally
applicable
analytes
selection
other
sensor–analyte
experiments.
Язык: Английский
A Review on the Rheological Properties of Single Amino Acids and Short Dipeptide Gels
Gels,
Год журнала:
2024,
Номер
10(8), С. 507 - 507
Опубликована: Авг. 1, 2024
Self-assembled
peptide-based
hydrogels
have
attracted
considerable
interest
from
the
research
community.
Particularly,
low
molecular
weight
gelators
(LMWGs)
consisting
of
amino
acids
and
short
peptides
are
highly
suitable
for
biological
applications
owing
to
their
facile
synthesis
scalability,
as
well
biocompatibility,
biodegradability,
stability
in
physiological
conditions.
However,
challenges
understanding
structure–property
relationship
lack
design
rules
hinder
development
new
with
required
properties
several
applications.
Hereby,
plethora
gelators,
this
review
discusses
mechanical
single
acid
dipeptide-based
hydrogels.
A
mutual
analysis
these
systems
allows
us
highlight
between
gel
sequence,
preparation
methods,
or
N
capping
groups.
Additionally,
recent
advancements
tuning
gels’
rheological
reviewed.
In
way,
present
aims
help
bridge
knowledge
gap
structure
properties,
easing
selection
Язык: Английский
Integrating Single-Walled Carbon Nanotubes into Supramolecular Assemblies: From Basic Interactions to Emerging Applications
ACS Nano,
Год журнала:
2024,
Номер
18(43), С. 29380 - 29393
Опубликована: Окт. 21, 2024
Integrating
single-walled
carbon
nanotubes
(SWCNTs)
into
supramolecular
self-assemblies
harnesses
the
distinctive
mechanical,
optical,
and
electronic
properties
of
nanoparticles
alongside
structural
chemical
assemblies.
Organic
molecules
capable
forming
assemblies
through
hydrophobic,
van
der
Waals,
π–π
interactions
have
been
demonstrated
to
be
particularly
effective
in
dispersing
functionalizing
SWCNTs,
as
these
same
facilitate
binding
hydrophobic
graphene-like
surface
SWCNTs.
This
review
discusses
a
variety
self-assembling
structures
that
were
shown
integrate
ranging
from
simple
micelles
ring
complex
DNA
origami
three-dimensional
hydrogels
formed
by
low-molecular-weight
gelators.
We
explore
integration
SWCNTs
various
highlight
emerging
applications
composite
materials,
such
mechanical
enforcement
leveraging
near-infrared
(NIR)
fluorescence
for
monitoring
molecular
self-assembly
process.
Notably,
NIR
which
overlaps
with
biological
transparency
window,
offers
significant
opportunities
noninvasive
sensing
within
platforms.
Future
research
deeper
understanding
between
different
frameworks
will
expand
potential
SWCNT-integrated
fields
like
biomedical
engineering,
devices,
environmental
sensing.
Язык: Английский
Tuning the morphology of supramolecular aggregates for nanocarrier‐based drug delivery
AIChE Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 22, 2024
Abstract
Due
to
the
unique
drug
delivery
mode
and
specific
therapy,
nano‐formulations
are
of
interest
for
biomedical
applications
treating
many
diseases.
However,
traditional
method
nano‐formulation
construction
via
additional
carriers
or
structural
modifications
therapeutic
drugs
might
be
cumbersome
low
loading‐efficient.
Herein,
kinetics,
accessible
pathways,
final
outcomes
supramolecular
assembly
processes
investigated
in
detail.
It
was
found
that
aggregates
cephradine
(CEP)
undergoes
a
morphological
transformation
from
anisotropic
nanofiber
(EtOH)
isotropic
spherical
nanoparticle
(H
2
O),
similar
“plants
took
root,
sprouted,
blossomed
bore
fruit.”
Moreover,
kinetics
results
reveal
pathways
nucleation
elongation
H
O
surface‐catalyzed
secondary
EtOH.
The
presented
this
work
has
potential
used
efficiently
designing
nano‐formulations.
Язык: Английский