Dual Functional Hydrogel of Osteoclastic-Inhibition and Osteogenic-Stimulation for Osteoporotic Bone Defect Regeneration DOI

Lei Yu,

Wentao Wang, Qian Chen

и другие.

Опубликована: Янв. 1, 2024

Язык: Английский

Recent advances in biopolymer-based smart hydrogel for wound healing DOI

Rohit Jaiswal,

Atul P. Sherje

Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 99, С. 105990 - 105990

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

14

Dual Functional Hydrogel of Osteoclastic-inhibition and Osteogenic-stimulation for Osteoporotic Bone Defect Regeneration DOI Creative Commons

Lei Yu,

Wentao Wang,

Chang Lv

и другие.

Materials Today Bio, Год журнала: 2025, Номер 31, С. 101550 - 101550

Опубликована: Фев. 6, 2025

Osteoporotic bone regeneration poses significant challenges due to the complexity of condition. Osteoporosis, a degenerative disorder, results from an imbalance in homeostasis driven by dysregulation osteoblast and osteoclast activity. This complicates treatment osteoporosis its related injuries clinical practice. Despite development various polymer scaffolds for defect repair, achieving effective osteoporotic bones-especially when combined with medications-remains difficult. In this study, we designed drug delivery system composed mesoporous bioactive glass (MBG) photo-crosslinked hyaluronic acid methacrylate (HAMA). system, loaded osteogenesis-promoting peptide DWIVA (D5) osteoclastogenesis-inhibiting alendronate (ALN), is gelled using light initiator 405 nm wavelength light. The MBG@D5-Gel complex enables controlled spatiotemporal release these agents, markedly enhancing conditions within ovariectomized rats inhibiting osteoclastogenesis resorption while promoting osteogenic differentiation mineralization. dual-action synergistically regulates activity, optimizing pathological microenvironment facilitating repair defects. holds great potential as organic-inorganic hybrid biomimetic implant material

Язык: Английский

Процитировано

1

Advancements in the chemistry of contact Lenses: Innovations and applications DOI Creative Commons

Abdulamier Ahmed Abdulamier,

Lina M. Shaker,

Ahmed A. Al‐Amiery

и другие.

Results in Chemistry, Год журнала: 2024, Номер unknown, С. 101872 - 101872

Опубликована: Окт. 1, 2024

Язык: Английский

Процитировано

4

Pharmaceutical Sciences: Insights and Observations from Academic Chairs and Vice Chairs DOI Creative Commons
Kristy M. Ainslie, Albert A. Bowers,

Robert H. Chichewicz

и другие.

The AAPS Journal, Год журнала: 2025, Номер 27(1)

Опубликована: Фев. 4, 2025

Язык: Английский

Процитировано

0

Prodrug-based combinational nanomedicine remodels lipid metabolism for reinforced ferroptosis and immune activation DOI Creative Commons
Ling Lin,

Zaixiang Fang,

Guohao Liu

и другие.

Acta Pharmaceutica Sinica B, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Blood-brain barrier crossing biopolymer activates immunity in primary brain lymphoma by targeting c-Myc and α-PD-1: Artificial intelligence analysis DOI
Vladimir A. Ljubimov, Tao Sun, Jiawei Wang

и другие.

Journal of Controlled Release, Год журнала: 2025, Номер unknown, С. 113611 - 113611

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Forty years Journal of Controlled Release: ‘Quality is not an act, it is a habit’ DOI
Stefaan C. De Smedt, Yu‐Kyoung Oh, Yoon Yeo

и другие.

Journal of Controlled Release, Год журнала: 2024, Номер 373, С. A1 - A4

Опубликована: Авг. 8, 2024

Язык: Английский

Процитировано

1

Direct synthesis of α-Carboxyl-ω-Hydroxyl polymers by catalyst and initiator in the same molecule DOI
Jie Zhang,

Siheng Zhang,

Jianda Niu

и другие.

European Polymer Journal, Год журнала: 2024, Номер unknown, С. 113656 - 113656

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

0

Dual Functional Hydrogel of Osteoclastic-Inhibition and Osteogenic-Stimulation for Osteoporotic Bone Defect Regeneration DOI

Lei Yu,

Wentao Wang, Qian Chen

и другие.

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0