European Polymer Journal, Journal Year: 2024, Volume and Issue: unknown, P. 113656 - 113656
Published: Dec. 1, 2024
Language: Английский
European Polymer Journal, Journal Year: 2024, Volume and Issue: unknown, P. 113656 - 113656
Published: Dec. 1, 2024
Language: Английский
Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 99, P. 105990 - 105990
Published: Sept. 1, 2024
Language: Английский
Citations
12Results in Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 101872 - 101872
Published: Oct. 1, 2024
Language: Английский
Citations
4Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101550 - 101550
Published: Feb. 6, 2025
Osteoporotic bone regeneration poses significant challenges due to the complexity of condition. Osteoporosis, a degenerative disorder, results from an imbalance in homeostasis driven by dysregulation osteoblast and osteoclast activity. This complicates treatment osteoporosis its related injuries clinical practice. Despite development various polymer scaffolds for defect repair, achieving effective osteoporotic bones-especially when combined with medications-remains difficult. In this study, we designed drug delivery system composed mesoporous bioactive glass (MBG) photo-crosslinked hyaluronic acid methacrylate (HAMA). system, loaded osteogenesis-promoting peptide DWIVA (D5) osteoclastogenesis-inhibiting alendronate (ALN), is gelled using light initiator 405 nm wavelength light. The MBG@D5-Gel complex enables controlled spatiotemporal release these agents, markedly enhancing conditions within ovariectomized rats inhibiting osteoclastogenesis resorption while promoting osteogenic differentiation mineralization. dual-action synergistically regulates activity, optimizing pathological microenvironment facilitating repair defects. holds great potential as organic-inorganic hybrid biomimetic implant material
Language: Английский
Citations
0Acta Pharmaceutica Sinica B, Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
Language: Английский
Citations
0The AAPS Journal, Journal Year: 2025, Volume and Issue: 27(1)
Published: Feb. 4, 2025
Language: Английский
Citations
0Journal of Controlled Release, Journal Year: 2025, Volume and Issue: unknown, P. 113611 - 113611
Published: March 1, 2025
Language: Английский
Citations
0Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 373, P. A1 - A4
Published: Aug. 8, 2024
Language: Английский
Citations
1Published: Jan. 1, 2024
Language: Английский
Citations
0European Polymer Journal, Journal Year: 2024, Volume and Issue: unknown, P. 113656 - 113656
Published: Dec. 1, 2024
Language: Английский
Citations
0