PEGylated PAMAM Dendrimer Nanoplatform for Co-delivery of Chemotherapeutic Agents and Inorganic Nanoparticles Enhancing Chemo-Photothermal Combination Therapy DOI

Binzhong Lu,

Yingying Yang, Xiang Li

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114688 - 114688

Опубликована: Апрель 1, 2025

Язык: Английский

Bidirectional regulation of reactive oxygen species for radiosensitization in nasopharyngeal carcinoma DOI Creative Commons
Jie Chen,

C. Q. Feng,

Yufei Lan

и другие.

Journal of Nanobiotechnology, Год журнала: 2025, Номер 23(1)

Опубликована: Фев. 8, 2025

Radiotherapy (RT) is the primary treatment modality for nasopharyngeal carcinoma (NPC). However, tumor microenvironment (TME)-induced radioresistance often compromises its therapeutic efficacy. Herein, we propose an innovative bidirectional radiosensitization strategy NPC. Specifically, have encapsulated metformin (Met) and copper sulfide nanoparticles (CuS NPs) within injectable DNA supramolecular hydrogels (DSH) to create a novel radiosensitizer, Met-CuS@DSH. This radiosensitizer not only effectively reverses hypoxia promote reactive oxygen species (ROS) generation but also significantly inhibits glutathione (GSH)-mediated ROS scavenging, thereby achieving by enhancing production suppressing scavenging. improves effect of NPC while reducing RT dose (3 Gy in total), which provides promising approach overcoming caused TME.

Язык: Английский

Процитировано

0
Copper/calcium co-doped carbon dots for targeted cancer therapy with dual-mode imaging and synergistic induction of cuproptosis and calcium-mediated apoptosis DOI

Wenqian Zheng,

Yang Liu, Jinru Liu

и другие.

Journal of Colloid and Interface Science, Год журнала: 2025, Номер unknown, С. 137337 - 137337

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Defect-Engineered Magnetic Bismuth Nanomedicine for Dual-Modal Imaging and Synergistic Lung Tumor Therapy DOI Creative Commons

Pengpeng Jia,

Jie Tu, Hongyu Shen

и другие.

Materials Today Bio, Год журнала: 2025, Номер unknown, С. 101680 - 101680

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
pH- and redox-sensitive selenium-incorporated mesoporous silica nanoparticles for osteosarcoma-targeted treatment DOI Creative Commons
Le He,

Zahra Javid Anbardan,

Pamela Habibović

и другие.

Materials & Design, Год журнала: 2025, Номер unknown, С. 113883 - 113883

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
PEGylated PAMAM Dendrimer Nanoplatform for Co-delivery of Chemotherapeutic Agents and Inorganic Nanoparticles Enhancing Chemo-Photothermal Combination Therapy DOI

Binzhong Lu,

Yingying Yang, Xiang Li

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114688 - 114688

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0