Advanced Therapeutics,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 9, 2024
Abstract
Glucose‐derived
carbon
nanospheres
(CSP),
uniquely
derived
by
hydrothermal
condensation
process,
inherently
cross
blood–brain‐barrier
(BBB)
but
distribute
all
over
the
brain.
Albeit
its
potential
to
treat
glioma
as
an
effective
drug
delivery
system,
it
is
challenging
restrict
drug‐associated
CSP
within
region
and
reduce
non‐specific
side
effects.
Incidentally,
gliomas
moderately
express
sigma
receptors
(SR).
Earlier,
a
cationic
lipid‐conjugated
neuropsychotic
drug,
haloperidol
(H8)
developed
with
SR‐targetability
anticancer
effect
zero
BBB‐crossing
ability.
In
this
study,
surface
modified
H8
(CH8
nano‐conjugate)
dual
targeting
achieved
glioma‐tumor
microenvironment:
1)
cells
2)
pro‐proliferative
M2
tumor‐associated
macrophages
(TAM),
both
SR.
CH8‐treatment
increases
survivability
of
orthotopic
bearing
mice
significantly
reduces
tumor
burden
in
glioma‐subcutaneous
model.
Further
CH8‐surface
combining
brain
carmustine
(CH8‐CRM).
CH8‐CRM
nano‐conjugate
selectively
enhances
glioma‐carrying
aggressiveness
comparison
other
treatment
groups.
Lysates
from
CH8‐CRM‐treated
show
upregulation
cleaved‐caspase
3,
p53,
downregulation
pAkt.
The
combination
pronouncedly
anti‐glioma
H8.
Conclusively,
CH8‐mediated
dual‐targeting
via
SR
glioma‐associated
exemplifies
repurposing
drugs
for
treating
glioma.
Advanced Industrial and Engineering Polymer Research,
Год журнала:
2023,
Номер
unknown
Опубликована: Сен. 1, 2023
Recent
developments
in
nanomaterials
have
come
to
extensive
use
various
fields,
especially
the
biomedical
industry.
Numerous
significant
obstacles
still
need
be
overcome,
particularly
those
about
utilizing
science,
before
they
can
used
for
medicinal
purposes.
Major
issues
biomedicine
include
biological
functioning,
harmony,
toxic
effects,
and
nano-bio
surface
properties.
Thus,
researchers
may
cutting-edge
characterization
approaches
study
applications.
Two-dimensional
polymers
are
crucial
components
of
systems.
Polymer-based
flexible
more
resistant
chemical
attack
than
other
NPs.
Polymers
easily
form
composite
or
functionalization
with
NPs
improve
their
performance
compared
traditional
The
current
review
article
discussed
nanomaterial
performance,
including
carbon
nanotubes
(CNTs),
graphene,
MXene
polymers-based
state
area
is
illustrated
this
summary
article,
along
applications
significance
approaches.
advanced
methods
examining
interior
geometry,
structure,
morphology
piece
writing,
Transmission
electron
microscopy
(TEM),
Scanning
electronic
(SEM),
Atomic
Force
Microscopy
(AFM),
Magnetic
resonance
force
(MRFM)
X-ray
diffraction
(XRD).
Finally,
authors
associated
European journal of medical research,
Год журнала:
2023,
Номер
28(1)
Опубликована: Ноя. 24, 2023
Abstract
This
paper
gives
a
detailed
analysis
of
nanotechnology's
rising
involvement
in
numerous
surgical
fields.
We
investigate
the
use
nanotechnology
orthopedic
surgery,
neurosurgery,
plastic
oncology,
heart
vascular
ophthalmic
thoracic
and
minimally
invasive
surgery.
The
details
how
helps
with
arthroplasty,
chondrogenesis,
tissue
regeneration,
wound
healing,
more.
It
also
discusses
employment
nanomaterials
implant
surfaces,
bone
grafting,
breast
implants,
among
other
things.
article
explores
various
uses,
including
stem
cell-incorporated
nano
scaffolds,
nano-surgery,
hemostasis,
nerve
nanorobots,
diagnostic
applications.
ethical
safety
implications
using
surgery
are
addressed.
future
possibilities
investigated,
pointing
to
possible
route
for
improved
patient
outcomes.
essay
finishes
comment
on
transformational
influence
applications
its
promise
breakthroughs.
Graphical
ACS Applied Bio Materials,
Год журнала:
2024,
Номер
7(3), С. 1336 - 1361
Опубликована: Фев. 27, 2024
Over
the
past
decade,
nanotechnology
has
seen
extensive
integration
into
biomedical
applications,
playing
a
crucial
role
in
biodetection,
drug
delivery,
and
diagnostic
imaging.
This
is
especially
important
reproductive
health
care,
which
become
an
emerging
significant
area
of
research.
Global
concerns
have
intensified
around
disorders
such
as
infertility,
endometriosis,
ectopic
pregnancy,
erectile
dysfunction,
benign
prostate
hyperplasia,
sexually
transmitted
infections,
cancers.
Nanotechnology
presents
promising
solutions
to
address
these
by
introducing
innovative
tools
techniques,
facilitating
early
detection,
targeted
improved
imaging
capabilities.
Through
utilization
nanoscale
materials
devices,
researchers
can
craft
treatments
that
are
not
only
more
precise
but
also
effective,
significantly
enhancing
outcomes
healthcare.
Looking
forward,
future
medicine
holds
immense
potential
for
reshaping
diagnostics,
personalized
therapies,
fertility
preservation.
The
nanotechnology-driven
delivery
systems
anticipated
elevate
treatment
effectiveness,
minimize
side
effects,
offer
patients
therapies
efficient.
review
aims
delve
various
types,
properties,
preparation
techniques
nanocarriers
specifically
designed
context
disorders,
shedding
light
on
current
landscape
directions
this
dynamic
field.
Advanced Materials Technologies,
Год журнала:
2024,
Номер
9(20)
Опубликована: Май 16, 2024
Abstract
The
convergence
of
advanced
nanotechnology
with
disease
diagnosis
has
ushered
in
a
transformative
era
healthcare,
empowering
early
and
accurate
detection
diseases
paving
the
way
for
timely
interventions,
improved
treatment
outcomes,
enhanced
patient
well‐being.
development
novel
materials
is
frequently
impetus
behind
significant
advancements
sensor
technology.
Among
them,
single‐walled
carbon
nanotubes
(SWCNTSs)
have
emerged
as
promising
nanomaterials
developing
biosensors.
Their
unique
optical,
electrical,
biocompatibility
properties
make
them
candidates
enhancing
sensitivity
real‐time
monitoring
capabilities
biosensors,
well
enabling
various
bioimaging
techniques.
Recent
studies
demonstrated
utility
SWCNTS‐based
biosensors
biological
analytes,
such
nitric
oxide
hydrogen
peroxide
(H
2
O
),
potential
implications
understanding
therapeutic
response
assessment.
Moreover,
SWCNTSs
shown
promise
applications,
including
fluorescence,
Raman
spectroscopy,
photoluminescence
imaging
samples.
This
article
delves
into
core
principles,
design
strategies,
operational
mechanisms
that
underpin
SWCNTS‐bioimaging
techniques‐based
It
emphasizes
on
their
versatile
functionalization
nanotubes,
laying
foundation
integration
biosensor
platforms
applications
aimed
at
diagnosing
wide
spectrum
infectious
diseases,
cancer,
neurological
disorders,
metabolic
conditions.
Polymers,
Год журнала:
2025,
Номер
17(7), С. 893 - 893
Опубликована: Март 26, 2025
Nanomaterials
have
demonstrated
significant
potential
in
enhancing
the
performance
and
functionality
of
composite
materials
across
various
industrial
applications.
This
review
delves
into
unique
properties
nanomaterials,
with
a
particular
focus
on
carbon-based
presents
key
findings
their
effectiveness
improving
performance.
The
study
emphasizes
specific
nano-based
materials,
highlighting
substantial
promise
advancing
field
nanocomposites.
Additionally,
it
addresses
challenges
associated
production
utilization
nanocomposite
discusses
solutions
to
overcome
these
obstacles.
concludes
recommendations
for
further
research
innovation
nanocomposites
fully
harness
advantages
advanced
broader
future
Advanced Materials Technologies,
Год журнала:
2024,
Номер
9(16)
Опубликована: Май 25, 2024
Abstract
Sensors
have
become
more
versatile
and
sophisticated
in
recent
years
to
fulfill
the
increasing
demands
for
human
health
applications.
Physiological
information
such
as
electrocardiogram,
pulse
rate,
respiration
are
essential
indications
of
personal
health,
often
collected
vitals,
which
typically
from
medical‐grade
electrocardiogram
(ECG)
machines.
In‐textile
sensors
a
fast‐growing
sub‐category
wearable
embedded
smart
textiles
acquire
physiological
movement
index
provide
harmful
chemical
warnings
without
compromising
comfortable
nature
clothing.
Recent
literature
has
shown
that
integrating
new
materials
greatly
improved
stability,
specificity,
selectivity
in‐textile
sensors.
For
example,
polyvinylidene
fluoride
nanofiber
produced
highly
stretchable
sensor
measure
ECG
readings
during
losing
data
quality.
This
review
discusses
group
nanomaterial‐based
consumer
use
home,
workplace,
healthcare
environments.
will
focus
on
exploring
analyzing
latest
developments
these
e‐textiles
due
their
ability
be
easily
integrated
daily
great
potential
medical
Future
work
necessary
incorporate
recycled
materials,
improve
method
powering
sensors,
ultimately
refine
designs
appropriate
sustainable
use.
Nanomaterials,
Год журнала:
2024,
Номер
14(15), С. 1291 - 1291
Опубликована: Июль 31, 2024
The
increasing
reliance
on
electronic
technologies
has
elevated
the
urgency
of
effective
electromagnetic
interference
(EMI)
shielding
materials.
This
review
explores
development
and
potential
magnetite-incorporated
one-dimensional
(1D)
carbon
nanostructure
hybrids,
focusing
their
unique
properties
synthesis
methods.
By
combining
magnetite’s
magnetic
with
electrical
conductivity
mechanical
strength
nanostructures
such
as
nanotubes
(CNTs)
fibers
(CFs),
these
hybrids
offer
superior
EMI
performance.
Various
techniques,
including
solvothermal
synthesis,
in
situ
growth,
electrostatic
self-assembly,
are
discussed
detail,
highlighting
impact
structure
resulting
composites.
also
addresses
challenges
achieving
homogeneous
dispersion
nanofillers
environmental
economic
considerations
large-scale
production.
hybrid
materials’
multifunctionality,
enhanced
strength,
thermal
stability,
resistance,
underscores
suitability
for
advanced
applications
aerospace,
electronics,
protection.
Future
research
directions
focus
optimizing
processes
exploring
new
configurations
to
further
improve
practical
applicability.
