The state of the art in anti-aging: plant-based phytochemicals for skin care
Immunity & Ageing,
Год журнала:
2025,
Номер
22(1)
Опубликована: Янв. 31, 2025
Phytochemicals
help
mitigate
skin
aging
by
scavenging
free
radicals,
modulating
key
enzymatic
pathways,
and
promoting
the
skin's
structural
integrity.
Carotenoids,
vitamins,
essential
fatty
acids,
phenolic
compounds
work
acting
as
antioxidants,
inhibiting
enzymes
like
hyaluronidase,
collagenase,
elastase,
which
degrade
structure,
reducing
levels
of
inflammatory
markers
(IL-6,
IL-8,
etc.)
matrix
metalloproteinases
(MMP-1,
MMP-2)
linked
to
aging.
Recent
research
highlights
that
plant-based
phytochemicals
can
improve
elasticity,
reduce
hyperpigmentation,
prevent
breakdown
important
proteins,
support
wound
healing,
making
them
valuable
components
for
care
treatments.
This
review
explores
multifaceted
roles
in
maintaining
improving
health,
highlighting
their
mechanisms
action
potential
anti-aging
innovations.
Язык: Английский
Critical Review on Orally Administered Nutricosmetics: Food-Based Solutions Conferring Skin Health from the inside out
Trends in Food Science & Technology,
Год журнала:
2025,
Номер
unknown, С. 104946 - 104946
Опубликована: Фев. 1, 2025
Язык: Английский
Instant and Multifunctional Nanofibers Loaded with Proanthocyanidins and Hyaluronic Acid for Skincare Applications
Biomedicines,
Год журнала:
2024,
Номер
12(7), С. 1584 - 1584
Опубликована: Июль 17, 2024
Hyaluronic-acid-
and
silk-fibroin-based
nanofibrous
mats
loaded
with
proanthocyanidins
collagen
peptides
were
fabricated
as
multifunctional
facial
masks
using
electrospinning.
Their
morphology,
hygroscopicity
moisture
retention,
DPPH,
ABTS
free
radical
scavenging
abilities,
cytocompatibility
investigated.
The
results
showed
that
the
dense
uniform,
an
average
diameter
ranging
from
300
to
370
nm.
exhibited
satisfactory
oxidation
resistance,
biocompatibility,
especially
excellent
capacities.
DPPH
activity
was
90%
15
mg/L
nanofibers,
0.005
nanofibers.
protected
fibroblasts
oxidative
stress
damage
induced
by
tert-butyl
hydroperoxide
(t-BHP)
significantly
promoted
their
proliferation.
Compared
traditional
liquid
semi-solid
masks,
prepared
in
this
study
contained
fewer
additives,
which
has
significant
advantages
terms
of
safety.
rapidly
dissolved
within
5
s
after
being
sprayed
water,
facilitated
release
penetration
active
ingredients
for
skincare.
Therefore,
displayed
indicating
promising
translational
potential
providing
a
valuable
reference
Язык: Английский
Electronic nose investigation and antioxidant assessment of CHARMS™ skincare cosmetics toward skin tone improvement
Deleted Journal,
Год журнала:
2024,
Номер
unknown, С. 100060 - 100060
Опубликована: Дек. 1, 2024
Язык: Английский
Efficient Production of the Colorless Carotenoid Phytoene in Yarrowia lipolytica through Metabolic Engineering
Kwanghyun Park,
Gyeongmin Kim,
Sungman Cha
и другие.
Journal of Agricultural and Food Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 19, 2024
Phytoene,
a
colorless
carotenoid
with
unique
ultraviolet
(UV)–B
absorption
properties,
offers
potential
for
applications
in
functional
food,
cosmetics,
and
therapeutics.
However,
their
low
natural
yield
poses
challenge
large-scale
production.
This
study
aims
to
enhance
phytoene
production
the
oleaginous
yeast
Yarrowia
lipolytica
by
introducing
heterologous
synthase
gene
combined
metabolic
engineering
approaches.
We
enhanced
synthesis
overexpressing
key
genes
mevalonate
pathway
compartmentalizing
biosynthetic
within
peroxisomes.
Moreover,
we
inhibited
glyoxylate
cycle
increase
accumulation
of
peroxisomal
acetyl-CoA
available
Our
engineered
strains
demonstrated
significant
production,
reaching
up
1.34
g/L
titer
58.74
mg/gDCW
flask-scale
fed-batch
culture,
which
are
highest
levels
reported
date.
These
results
underscore
Y.
as
robust
platform
producing
phytoenes
other
terpenoids
on
an
industrial
scale,
offering
valuable
insights
future
efforts
engineering.
Язык: Английский