Recent advances in the extraction, purification and analytical techniques for flavonoids from plants: Taking hawthorn as an example
Journal of Food Composition and Analysis,
Год журнала:
2025,
Номер
unknown, С. 107372 - 107372
Опубликована: Фев. 1, 2025
Язык: Английский
The Multifaceted Anti-Atherosclerotic Properties of Herbal Flavonoids: A Comprehensive Review
Pharmacological Research,
Год журнала:
2024,
Номер
211, С. 107551 - 107551
Опубликована: Дек. 18, 2024
Язык: Английский
The Role of Alarmins in the Pathogenesis of Atherosclerosis and Myocardial Infarction
Current Issues in Molecular Biology,
Год журнала:
2024,
Номер
46(8), С. 8995 - 9015
Опубликована: Авг. 17, 2024
Atherosclerosis
is
a
condition
that
associated
with
lipid
accumulation
in
the
arterial
intima.
Consequently,
enlarging
lesion,
which
also
known
as
an
atherosclerotic
plaque,
may
close
blood
vessel
lumen,
thus
leading
to
organ
ischaemia.
Furthermore,
plaque
rupture
and
initiate
formation
of
thrombus,
can
cause
acute
background
pathological
eventually
lead
major
cardiovascular
diseases
such
coronary
syndrome
or
ischaemic
stroke.
The
disorder
altered
profile
alarmins,
stress
response
molecules
are
secreted
due
cell
injury
death
induce
inflammatory
responses.
High-mobility
group
box
1
(HMGB1),
S100
proteins,
interleukin-33,
heat
shock
proteins
(HSPs)
affect
behaviour
endothelial
cells
vascular
smooth
muscle
(VSMCs).
Thus,
alarmins
control
responses
proliferation
VSMCs,
two
important
processes
implicated
pathogenesis
atherosclerosis.
In
this
review,
we
will
discuss
role
pathophysiology
atherosclerosis
myocardial
infarction.
Язык: Английский
A Comprehensive Review on the Isolation, Bioactivities, and Structure–Activity Relationship of Hawthorn Pectin and Its Derived Oligosaccharides
Foods,
Год журнала:
2024,
Номер
13(17), С. 2750 - 2750
Опубликована: Авг. 29, 2024
Hawthorn
(
Язык: Английский
LOX-1 as a biological marker and therapeutic target in cardiovascular pathology (literature review)
Consilium Medicum,
Год журнала:
2024,
Номер
26(10), С. 666 - 673
Опубликована: Ноя. 23, 2024
Cardiovascular
diseases
(CVD)
are
a
global
medical,
social
and
economic
problem.
Currently,
the
search
study
of
new
biological
markers
that
can
provide
early
diagnosis
CVD,
serve
as
laboratory
tool
for
evaluating
effectiveness
treatment
or
be
used
prognostic
criteria
risk
stratification
continues.
The
interest
scientists
is
focused
on
type
1
lectin-like
receptor
oxidized
low-density
lipoproteins
(LOX-1)
diagnostic
marker
in
CVD.
presented
literature
review
highlights
potential
significance
LOX-1
It
expected
future
clinical
experimental
studies
will
confirm
possibility
using
an
additional
non-invasive
prognosis
assessment
patients
with
Modulation
levels
expression
pharmacological
drugs
may
prove
to
promising
direction
Язык: Английский
Analysis of Major Chemical Constituents in Jiuwei Decoction Based On Capillary Electrophoresis Coupled With Quadrupole Time‐of‐Flight Mass Spectrometry
Electrophoresis,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 24, 2024
An
analytical
method
for
identifying
the
chemical
constituents
in
Chinese
herbal
combination
Jiuwei
decoction
was
established
using
capillary
electrophoresis
coupled
with
quadrupole
time-of-flight
mass
spectrometry.
Nine
herbs
were
extracted
a
60:40
(v/v)
ethanol/water
solution
to
prepare
decoction.
Electrophoretic
separation
carried
out
50
µm
i.d.,
125
cm
bare
fused
silica
at
constant
temperature
of
25°C
sample
injection.
The
composition
analyzed
and
identified
both
positive
negative
ion
modes.
In
mode,
voltage
30
kV
applied,
1%
aqueous
formic
acid
serving
as
background
electrolyte
(BGE),
along
50:50
methanol/water
containing
0.1%
sheath
liquid.
-30
employed,
utilizing
mM
ammonium
acetate
(pH
9.0)
BGE,
combined
5
MassHunter
Qualitative
Analysis
software
(version
10.0)
utilized
identify
52
compounds
based
on
accurate
mass,
isotope
abundance,
isotopic
patterns,
fragmentation
information.
data
compared
Agilent
Personal
Compound
Database
Library
traditional
medicine
(TCM),
well
multiple
online
databases
(TCMSP,
ChemSpider,
PubChem,
PubMed,
Web
Science)
relevant
literature.
pathways
representative
also
characterized.
This
study
decoction,
providing
molecular
basis
further
exploration
its
pharmacological
effects
presenting
robust
methodology
compositional
analysis
complex
TCM
mixtures.
Язык: Английский