Environment & Health,
Год журнала:
2025,
Номер
3(4), С. 425 - 435
Опубликована: Янв. 29, 2025
Conventional
metrics
for
tracking
infectious
diseases,
including
case
and
outbreak
data
syndromic
surveillance,
can
be
resource-intensive,
misleading,
comparatively
slow
with
prolonged
collection,
analysis
authentication.
This
study
examined
the
2022–2023
Respiratory
Syncytial
Virus
(RSV)
season
in
a
contiguous
metropolitan
area
connected
by
an
active
international
land
border,
affording
opportunity
comparison
of
respiratory
virus
spanning
two
independent
public
health
jurisdictions.
Time-lagged
cross
correlation
qualitative
examination
wastewater
signals
showed
that
peak
Detroit
(MI,
USA)
RSV
predated
Windsor
(ON,
Canada)
approximately
5
weeks.
A
strong
positive
relationship
was
observed
between
N-gene
concentrations
hospitalization
rates
Windsor-Essex
(Kendall's
τ
=
0.539,
p
≤
0.001,
Spearman's
ρ
0.713,
0.001)
as
well
0.739,
0.888,
0.001).
demonstrated
surveillance
reveal
regional
differences
infection
dynamics
communities
provide
measure
prevalence
RSV,
underreported
disease.
These
findings
support
use
cost-effective
tool
monitoring
to
enhance
existing
systems
better
inform
disease
mitigation
strategies.
Clinical Microbiology Reviews,
Год журнала:
2023,
Номер
37(1)
Опубликована: Дек. 14, 2023
SUMMARY
Wastewater-based
surveillance
(WBS)
has
undergone
dramatic
advancement
in
the
context
of
coronavirus
disease
2019
(COVID-19)
pandemic.
The
power
and
potential
this
platform
technology
were
rapidly
realized
when
it
became
evident
that
not
only
did
WBS-measured
SARS-CoV-2
RNA
correlate
strongly
with
COVID-19
clinical
within
monitored
populations
but
also,
fact,
functioned
as
a
leading
indicator.
Teams
from
across
globe
innovated
novel
approaches
by
which
wastewater
could
be
collected
diverse
sewersheds
ranging
treatment
plants
(enabling
community-level
surveillance)
to
more
granular
locations
including
individual
neighborhoods
high-risk
buildings
such
long-term
care
facilities
(LTCF).
Efficient
processes
enabled
extraction
concentration
highly
dilute
matrix.
Molecular
genomic
tools
identify,
quantify,
characterize
its
various
variants
adapted
programs
applied
these
mixed
environmental
systems.
Novel
data-sharing
allowed
information
mobilized
made
immediately
available
public
health
government
decision-makers
even
public,
enabling
evidence-informed
decision-making
based
on
local
dynamics.
WBS
since
been
recognized
tool
transformative
potential,
providing
near-real-time
cost-effective,
objective,
comprehensive,
inclusive
data
changing
prevalence
measured
analytes
space
time
populations.
However,
consequence
rapid
innovation
hundreds
teams
simultaneously,
tremendous
heterogeneity
currently
exists
literature.
This
manuscript
provides
state-of-the-art
review
established
details
current
work
underway
expanding
scope
other
infectious
targets.
Journal of Hazardous Materials,
Год журнала:
2024,
Номер
466, С. 133637 - 133637
Опубликована: Янв. 29, 2024
Addressing
per-and
polyfluoroalkyl
substances
(PFAS)
contamination
is
an
urgent
environmental
concern.
While
most
research
has
focused
on
PFAS
in
water
matrices,
comparatively
little
attention
been
given
to
sludge,
a
significant
by-product
of
wastewater
treatment.
This
critical
review
presents
the
latest
information
emission
sources,
global
distribution,
international
regulations,
analytical
methods,
and
remediation
technologies
for
sludge
biosolids
from
treatment
plants.
concentrations
matrices
are
typically
hundreds
ng/g
dry
weight
(dw)
developed
countries
but
rarely
reported
developing
least-developed
due
limited
capability.
In
comparison
samples,
efficient
extraction
cleaning
procedures
crucial
detection
samples.
regulations
have
mainly
soil
reuse,
only
two
set
limits
or
with
maximum
100
dw
major
PFAS.
Biological
using
microbes
enzymes
present
considered
as
having
high
potential
remediation,
they
eco-friendly,
low-cost,
promising.
By
contrast,
physical/chemical
methods
either
energy-intensive
linked
further
challenges
disposal.
The
findings
this
deepen
our
comprehension
guided
future
recommendations.
The Science of The Total Environment,
Год журнала:
2022,
Номер
858, С. 159350 - 159350
Опубликована: Окт. 18, 2022
Wastewater
based
epidemiology
(WBE)
is
an
important
tool
to
fight
against
COVID-19
as
it
provides
insights
into
the
health
status
of
targeted
population
from
a
small
single
house
large
municipality
in
cost-effective,
rapid,
and
non-invasive
way.
The
implementation
wastewater
surveillance
(WBS)
could
reduce
burden
on
public
system,
management
pandemics,
help
make
informed
decisions,
protect
health.
In
this
study,
with
patients
was
for
monitoring
prevalence
SARS-CoV-2
genetic
markers
samples
(WS)
clinical
specimens
(CS)
period
30
days.
RT-qPCR
technique
employed
target
nonstructural
(ORF1ab)
structural-nucleocapsid
(N)
protein
genes
SARS-CoV-2,
according
validated
experimental
protocol.
Physiological,
environmental,
biological
parameters
were
also
measured
following
American
Public
Health
Association
(APHA)
standard
protocols.
viral
shedding
peaked
when
highest
number
cases
clinically
diagnosed.
Throughout
study
period,
7450
23,000
gene
copies/1000
mL
detected,
where
we
identified
47
%
(57/120)
positive
WS
35
(128/360)
CS.
When
patient
lowest
(2),
CT
value
(39.4;
i.e.,
copy
number)
WS.
On
other
hand,
(6),
(25.2
numbers)
obtained
An
advance
signal
increased
load
found
earlier
than
Using
customized
primer
sets
traditional
PCR
approach,
confirmed
that
all
variants
both
CS
Delta
(B.1.617.2).
To
our
knowledge,
first
follow-up
determine
temporal
relationship
between
their
discharge
RNA
including
family
members
sampling
developing
country
(Bangladesh),
proper
sewage
system
lacking.
salient
findings
indicate
virus
identify
cases,
which
reduces
during
pandemics.
Nature Communications,
Год журнала:
2023,
Номер
14(1)
Опубликована: Июль 28, 2023
Although
the
coronavirus
disease
(COVID-19)
emergency
status
is
easing,
COVID-19
pandemic
continues
to
affect
healthcare
systems
globally.
It
crucial
have
a
reliable
and
population-wide
prediction
tool
for
estimating
COVID-19-induced
hospital
admissions.
We
evaluated
feasibility
of
using
wastewater-based
epidemiology
(WBE)
predict
weekly
new
hospitalizations
in
159
counties
across
45
states
United
States
America
(USA),
covering
population
nearly
100
million.
Using
county-level
wastewater
surveillance
data
(over
20
months),
WBE-based
models
were
established
through
random
forest
algorithm.
accurately
predicted
admissions,
allowing
preparation
window
1-4
weeks.
In
real
applications,
periodically
updated
showed
good
accuracy
transferability,
with
mean
absolute
error
within
4-6
patients/100k
upcoming
hospitalization
numbers.
Our
study
demonstrated
potential
WBE
as
an
effective
method
provide
early
warnings
systems.
