Multilevel Toxicity Evaluations of Polyethylene Microplastics in Zebrafish (Danio rerio) DOI Open Access

Ingrid de Souza Freire,

Maria Luiza Fascineli, Tathyana Benetis Piau

и другие.

International Journal of Environmental Research and Public Health, Год журнала: 2023, Номер 20(4), С. 3617 - 3617

Опубликована: Фев. 17, 2023

Microplastics in freshwater environments pose a serious threat to living beings. Polyethylene microplastics (PE-MP) are the type most used around world as microbeads personal care products, and they have been found aquatic organisms. The behavior toxicity of fluorescent PE-MP spheres with an average diameter 58.9 μm were studied adult, juvenile embryo zebrafish (Danio rerio). adults for genotoxicity, cytotoxicity, histology biochemical markers. Juveniles underwent follow-up gastrointestinal (GI) tract histologic observations, embryos embryotoxicity FET-test. In adults, micronucleus test comet assays neither genotoxicity after acute exposure 96 h at concentrations 0.0, 12.5, 50 100 mg.L−1, nor cytotoxicity through nuclear abnormalities test. Acetylcholinesterase (AChE), Glutathione-S-Transferase (GST) Lactate Dehydrogenase (LDH) activities measured exposed h. AChE GST significantly changed, while no changes occurred LDH. conclusion, these did not cause toxic effects because there was internalization. observed may be associated GI microbiological dysbiosis, previously reported. intestine juveniles remained present 12–15 days on post-exposure clearance study, showing slow depuration. histological analysis, internalization microbeads, complete cross chorion barrier, embryotoxic exposures 6.25, 50.0 or 100.0 mg.L−1

Язык: Английский

Nanoplastic Exposure at Environmental Concentrations Disrupts Hepatic Lipid Metabolism through Oxidative Stress Induction and Endoplasmic Reticulum Homeostasis Perturbation DOI
Weiyu Wang,

Xuan Mao,

Rui Zhang

и другие.

Environmental Science & Technology, Год журнала: 2023, Номер 57(38), С. 14127 - 14137

Опубликована: Сен. 8, 2023

In this study, we investigated the mechanism underlying perturbation of hepatic lipid metabolism in response to micro/nanoplastic (MP/NP) exposure at environmentally relevant concentrations. Polystyrene (PS) MPs/NPs with different sizes (0.1, 0.5, and 5.0 μm) were studied for their effects on homeostasis function Nile tilapia (Oreochromis niloticus) liver. Results showed that PS readily internalized accumulated various internal organs/tissues, especially fish liver muscle. Smaller-sized NPs caused more severe toxicity than larger MPs, including steatosis, inflammatory response, disturbed function. Mechanistically, a particle size 100 nm perturbed protein endoplasmic reticulum (ER) by inhibiting expression chaperone proteins genes involved ER-associated degradation. This led activation PERK-eIF2α pathway, which dysfunction metabolism. Induction oxidative stress Nrf2/Keap1 pathway also NP-induced accumulation. These findings highlight potential adverse environmental aquatic organisms, raising concerns about ecotoxicity food safety.

Язык: Английский

Процитировано

47

Occurrence, bioaccumulation, fate, and risk assessment of emerging pollutants in aquatic environments: A review DOI

Yuange Yu,

Zhu Wang,

Bin Yao

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 923, С. 171388 - 171388

Опубликована: Март 1, 2024

Язык: Английский

Процитировано

28

Metabolomic disorders unveil hepatotoxicity of environmental microplastics in wild fish Serranus scriba (Linnaeus 1758) DOI

Nesrine Zitouni,

Tiziana Cappello, Omayma Missawi

и другие.

The Science of The Total Environment, Год журнала: 2022, Номер 838, С. 155872 - 155872

Опубликована: Май 13, 2022

Язык: Английский

Процитировано

52

Adverse effects of polystyrene microplastics in the freshwater commercial fish, grass carp (Ctenopharyngodon idella): Emphasis on physiological response and intestinal microbiome DOI
Yaotong Hao,

Yanfeng Sun,

Mo Li

и другие.

The Science of The Total Environment, Год журнала: 2022, Номер 856, С. 159270 - 159270

Опубликована: Окт. 6, 2022

Язык: Английский

Процитировано

51

Interactive effects of polystyrene nanoplastics and 6:2 chlorinated polyfluorinated ether sulfonates on the histomorphology, oxidative stress and gut microbiota in Hainan Medaka (Oryzias curvinotus) DOI
Dandan Gao,

Chunmiao Kong,

Hongping Liao

и другие.

The Science of The Total Environment, Год журнала: 2023, Номер 880, С. 163307 - 163307

Опубликована: Апрель 6, 2023

Язык: Английский

Процитировано

24

Development of bifunctional biochar/iron oxide composites for tetracycline removal from synthetic wastewater DOI Creative Commons

Pedro Anabalón Fuentes,

Matias Kopp Pailañir,

Sebastian Rocha Mella

и другие.

Journal of Water Process Engineering, Год журнала: 2024, Номер 64, С. 105509 - 105509

Опубликована: Июнь 9, 2024

Язык: Английский

Процитировано

10

Genes of filter-feeding species as a potential toolkit for monitoring microplastic impacts DOI
Marta Pilar Ortiz-Moriano, Eva García‐Vázquez, Gonzalo Machado‐Schiaffino

и другие.

Aquatic Toxicology, Год журнала: 2025, Номер 279, С. 107234 - 107234

Опубликована: Янв. 5, 2025

Язык: Английский

Процитировано

1

A review of interactions of microplastics and typical pollutants from toxicokinetics and toxicodynamics perspective DOI
Ning Gao, Lanpeng Yang, Xueqiang Lu

и другие.

Journal of Hazardous Materials, Год журнала: 2022, Номер 432, С. 128736 - 128736

Опубликована: Март 19, 2022

Язык: Английский

Процитировано

35

Impacts of microplastics and carbamazepine on the shell formation of thick-shell mussels and the underlying mechanisms of action DOI
Yihan Yu,

Dandan Tian,

Yu Han

и другие.

The Science of The Total Environment, Год журнала: 2022, Номер 838, С. 156442 - 156442

Опубликована: Июнь 2, 2022

Язык: Английский

Процитировано

34

Multiple endpoints of polyethylene microplastics toxicity in vascular plants of freshwater ecosystems: A study involving Salvinia auriculata (Salviniaceae) DOI
Alex Rodrigues Gomes,

Ítalo Nascimento Freitas,

Thiarlen Marinho da Luz

и другие.

Journal of Hazardous Materials, Год журнала: 2023, Номер 450, С. 131069 - 131069

Опубликована: Фев. 24, 2023

Язык: Английский

Процитировано

20