Dual-recognition “turn-off-on” fluorescent Biosensor triphenylamine-based continuous detection of copper ion and glyphosate applicated in environment and living system

Journal of Hazardous Materials, Год журнала: 2024, Номер 477, С. 135216 - 135216

Опубликована: Июль 23, 2024

Язык: Английский

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A Turn‐On Fluorescence Probe for Rapidly Sensing Exogenous and Endogenous Hydrogen Peroxide in Living Cells

ChemistrySelect, Год журнала: 2025, Номер 10(5)

Опубликована: Фев. 1, 2025

Abstract Monitoring abnormal changes in hydrogen peroxide (H 2 O ) levels mammalian cells is essential to understanding its physicochemical functions biological systems. Generally, H fluorescent probes used for intracellular monitoring are limited the long response time and low sensitivity. Herein, 1,8‐naphthimide‐based probe (NPB) with excellent photostability was confirmed be an specific due oxidation of borate ester phenol. Compared previously reported molecular probes, NPB displayed improved performance detection, such as photostability, good anti‐interference, high selectivity, fast (10 s), detection limit (15 nM). Furthermore, most outstanding advantage as‐prepared mitochondrial‐targeting ability a Pearson's colocalization coefficient 0.91. Meanwhile, biocompatibility successfully utilized imaging exogenous endogenous living cells. The sensing mechanism further carefully demonstrated proposed involve phenol by H₂O₂. We anticipated that should have broad application chemical analysis reveal physiological function vivo.

Язык: Английский

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Thermal decomposition synthesis of Sr- modified ZnS quantum dots for hydrogen peroxide electrochemical sensing

Electrochimica Acta, Год журнала: 2025, Номер unknown, С. 146124 - 146124

Опубликована: Март 1, 2025

Язык: Английский

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Detrimental impact of photo-Fenton treated COVID-19 drugs on liver function: A thorough investigation in Danio rerio

Journal of Environmental Management, Год журнала: 2025, Номер 381, С. 125182 - 125182

Опубликована: Апрель 10, 2025

Язык: Английский

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Recent Advances in Fluorescent Probe for Detecting Biorelevant Analytes during Stress in Plants

Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 28, 2025

Plants are constantly exposed to various stressors that can severely hinder their growth and threaten agricultural productivity. Recent advancements in plant imaging using fluorescent probes have opened new avenues for exploring the intricate processes involved stress perception signaling. This review represents comprehensive effort consolidate recent advances probe technologies, encompassing small-molecule probes, nanoprobes, genetically encoded indicators, as revolutionary tools deciphering stress-induced physiological dynamics. We present a classification of designed detecting key biomolecules responses, including reactive species, phytohormones, enzymes, other signaling molecules. By critically evaluating design principles, practical applications, distinct advantages over conventional analytical methods, we aim empower scientists unraveling spatiotemporal regulation networks. Finally, propose strategic directions overcome current technical bottlenecks maximize potential fluorescence-based sensing advancing sustainable agriculture.

Язык: Английский

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A highly sensitive and selective chemiluminescent probe for peroxynitrite detection in vitro, in vivo and in human liver cancer tissue

Journal of Hazardous Materials, Год журнала: 2024, Номер 469, С. 134094 - 134094

Опубликована: Март 20, 2024

Язык: Английский

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Shortening the early diagnostic window of Hg2+-induced liver injury with a H2O2-activated fluorescence/afterglow imaging assay

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 136059 - 136059

Опубликована: Окт. 4, 2024

Язык: Английский

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The first specific probe for pyrrolidine with multifunction by the interaction mechanism of atomic economic reaction

iScience, Год журнала: 2024, Номер 27(7), С. 110024 - 110024

Опубликована: Май 18, 2024

Pyrrolidine (PyD) has an important impact on the environment and human health. However, there is currently no method for trace detection of PyD. Here, we successfully designed diaminomethylene-4H-pyran (1) as first specific fluorescent probe Only by adding PyD to 1, blue fluorescence at 455 nm, color solution changes from colorless yellow. The limit 1.12 × 10

Язык: Английский

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Visualizing DNA/RNA, Proteins, and Small Molecule Metabolites within Live Cells

Small, Год журнала: 2024, Номер 20(46)

Опубликована: Авг. 3, 2024

Live cell imaging is essential for obtaining spatial and temporal insights into dynamic molecular events within heterogeneous individual cells, in situ intracellular networks, vivo organisms. Molecular tracking live cells also a critical general requirement studying physiological processes biology, cancer, developmental neuroscience. Alongside this context, review provides comprehensive overview of recent research progress live-cell RNAs, DNAs, proteins, small-molecule metabolites, as well their applications diagnosis, immunodiagnosis, biochemical diagnosis. A series advanced techniques have been introduced summarized, including high-precision imaging, high-resolution low-abundance multidimensional multipath rapid computationally driven methods, all which offer valuable disease prevention, treatment. This article addresses the current challenges, potential solutions, future development prospects field.

Язык: Английский

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"All in one" lipid-polymer nanodelivery system for gene therapy of ischemic diseases

Biomaterials, Год журнала: 2024, Номер 313, С. 122799 - 122799

Опубликована: Сен. 3, 2024

Язык: Английский

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