Prevalence of Olfactory Dysfunction with the Omicron Variant of SARS-CoV-2: A Systematic Review and Meta-Analysis
Cells,
Год журнала:
2023,
Номер
12(3), С. 430 - 430
Опубликована: Янв. 28, 2023
The
omicron
variant
is
thought
to
cause
less
olfactory
dysfunction
than
previous
variants
of
SARS-CoV-2,
but
the
reported
prevalence
differs
greatly
between
populations
and
studies.
Our
systematic
review
meta-analysis
provide
information
regarding
regional
differences
in
as
well
an
estimate
global
based
on
62
studies
reporting
626,035
patients
infected
with
variant.
omicron-induced
European
ancestry
11.7%,
while
it
significantly
lower
all
other
populations,
ranging
1.9%
4.9%.
When
ethnic
population
sizes
are
considered,
adults
estimated
be
3.7%.
Omicron's
effect
olfaction
twofold
tenfold
that
alpha
or
delta
according
meta-analyses
our
analysis
directly
compared
variants.
profile
ethnicities
mirrors
results
a
recent
genome-wide
association
study
connected
gene
locus
encoding
odorant-metabolizing
enzyme,
UDP
glycosyltransferase,
extent
COVID-19-related
loss
smell.
consistent
hypothesis
this
enzyme
contributes
observed
differences.
Язык: Английский
Impact of variants of SARS-CoV-2 on obstetrical and neonatal outcomes
Journal of Gynecology Obstetrics and Human Reproduction,
Год журнала:
2023,
Номер
52(4), С. 102566 - 102566
Опубликована: Март 2, 2023
Язык: Английский
Pre-Delta, Delta, and Omicron Periods of the Coronavirus Disease 2019 (COVID-19) Pandemic and Health Outcomes During Delivery Hospitalization
Obstetrics and Gynecology,
Год журнала:
2023,
Номер
unknown
Опубликована: Ноя. 2, 2023
To
examine
the
relationship
between
coronavirus
disease
2019
(COVID-19)
diagnosis
at
delivery
and
adverse
maternal
health
pregnancy
outcomes
during
pre-Delta,
Delta,
Omicron
variant
predominance,
with
a
focus
on
time
period
of
predominance.
Язык: Английский
Prevalence of Olfactory Dysfunction with the Omicron Variant of SARS-CoV-2: A Systematic Review and Meta-analysis
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2022,
Номер
unknown
Опубликована: Дек. 16, 2022
Abstract
The
omicron
variant
is
thought
to
cause
less
olfactory
dysfunction
than
previous
variants
of
SARS-CoV-2,
but
the
reported
prevalence
differs
greatly
between
populations
and
studies.
Our
systematic
review
meta-analysis
provide
information
about
regional
differences
in
as
well
an
estimate
global
based
on
62
studies
reporting
626,035
patients
infected
with
variant.
omicron-induced
European
ancestry
11.7%,
while
it
significantly
lower
all
other
populations,
ranging
1.9%
4.9%.
When
ethnic
population
sizes
are
taken
into
account,
adults
estimated
at
3.7%.
Omicron’s
effect
olfaction
twofold
tenfold
that
alpha
or
delta
variant,
according
meta-analyses
our
analysis
directly
compared
variants.
profile
ethnicities
mirrors
results
a
recent
genome-wide
association
study
implicated
gene
locus
encoding
odorant-metabolizing
enzyme,
UDP
glycosyltransferase,
be
linked
extent
COVID-related
loss
smell.
consistent
hypothesis
this
enzyme
contributes
observed
differences.
Язык: Английский
Maternal and Perinatal Outcomes of SARS-CoV-2 and Variants in Pregnancy
Maternal-Fetal Medicine,
Год журнала:
2023,
Номер
5(2), С. 104 - 114
Опубликована: Март 27, 2023
Abstract
Pregnancy
is
a
physiological
state
that
predisposes
women
to
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
infection,
disease
can
cause
adverse
maternal
and
perinatal
outcomes.
The
severity
of
2019
(COVID-19)
known
vary
by
viral
strain;
however,
evidence
for
the
effects
this
virus
in
pregnant
has
yet
be
fully
elucidated.
In
review,
we
describe
outcomes,
vaccination,
vertical
transmission,
among
infected
with
different
SARS-CoV-2
variants
identified
date.
We
also
summarize
existing
outcomes
specific
information
relating
variants.
Our
analysis
showed
Omicron
infection
was
associated
fewer
while
Delta
variant
worse
pregnancy
Maternal
deaths
arising
from
COVID-19
were
found
rare
(<1.0%),
irrespective
whether
wild-type
strain
or
variant.
Severe
morbidity
more
frequent
(10.3%),
followed
Alpha
(4.7%),
(4.5%),
(2.9%)
rates
stillbirth
0.8%,
4.1%,
3.1%,
2.3%,
respectively,
pregnancies
strain,
Alpha,
Delta,
variants,
respectively.
Preterm
birth
admission
neonatal
intensive
care
units
common
cases
(19.0%
18.62%,
respectively),
risks
similar
those
(14.7%
11.2%,
(14.9%
13.1%),
(13.2%
13.8%,
respectively).
As
remains
global
pandemic,
new
continue
emerge,
research
impact
on
needs
expanded.
Язык: Английский
Placental Infection Associated with SARS-CoV-2 Wildtype Variant and Variants of Concern
Viruses,
Год журнала:
2023,
Номер
15(9), С. 1918 - 1918
Опубликована: Сен. 13, 2023
The
original
SARS-CoV-2
lineages
have
been
replaced
by
successive
variants
of
concern
(VOCs)
over
time.
aim
this
study
was
to
perform
an
assessment
the
placental
infection
according
predominant
variant
at
moment
COVID-19
diagnosis.
This
a
prospective
SARS-CoV-2-positive
pregnant
women
between
March
2020
and
2022.
population
divided
into
pregnancies
affected
disease
during
(Pre-VOC
group)
after
December
(VOC
group).
presence
virus
assessed
RT-PCR,
viral
determined
whole
genome
sequencing.
A
total
104
placentas
were
examined,
among
which
54
cases
belonged
Pre-VOC
group
50
VOC
group.
Sixteen
positive
RT-PCR
tests
for
reported.
NGS
analysis
confirmed
lineage
in
placenta
tissue.
All
samples
corresponded
group,
whereas
no
detected
(16,
29.6%
vs.
0,
0.0%
p
=
0.000).
Preterm
birth
(9,
16.7%
2,
4%;
0.036)
hypertensive
disorders
pregnancy
(14,
25.9%
3,
6%;
0.003)
more
frequent
than
Finally,
composed
23
unvaccinated
27
vaccinated
women;
differences
observed
sub-analysis
focused
on
vaccination
status.
In
summary,
only
infected
wildtype.
Thus,
could
be
influenced
variants,
timing,
or
According
our
data,
current
risk
maternal
COVID
should
updated.
Язык: Английский
Neonatal COVID-19 treatment: Are there new chances?
Journal of Neonatal-Perinatal Medicine,
Год журнала:
2024,
Номер
17(4), С. 501 - 507
Опубликована: Май 14, 2024
Coronavirus
disease
2019
(COVID-19)
is
considered
an
infectious
which
caused
by
infection
with
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2).
Neonatal
COVID-19
had
been
occurred
in
many
countries
would
indicate
the
need
of
effective
and
safe
treatment
for
these
vulnerable
group.
In
this
study,
we
showed
symptoms
corona
virus
neonates,
investigation
neonates
radiological
features
neonatal
COVID-19.
addition,
discussed
management
COVI-19,
antiviral
treatment,
monoclonal
antibodies
administration,
immunomodulatory
therapy,
antibiotics,
vitamins,
minerals
COVID-19,
also
telemedicine
feeding
newborn
mother.
We
multisystem
inflammatory
(MIS-N),
affected
discussion
complication
further
methods
dealing
research
done
on
treatment.
Язык: Английский
Association between physical activity status and severity of COVID-19 in older adults
Epidemiology and Infection,
Год журнала:
2022,
Номер
150
Опубликована: Янв. 1, 2022
Abstract
The
risk
factors
specific
to
the
elderly
population
for
severe
coronavirus
disease
2019
(COVID-19)
caused
by
Omicron
variant
of
concern
(VOC)
are
not
yet
clear.
We
performed
an
exploratory
analysis
using
logistic
regression
identify
COVID-19
illness
among
4,868
older
adults
with
a
positive
acute
respiratory
2
(SARS-CoV-2)
test
result
who
were
admitted
healthcare
facility
between
1
January
2022
and
16
May
2022.
then
conducted
one-to-one
propensity
score
(PS)
matching
three
–
dementia,
admission
from
long-term
care
poor
physical
activity
status
used
Fisher's
exact
compare
proportion
cases
in
matched
data.
also
estimated
average
treatment
effect
on
treated
(ATT)
each
PS
analysis.
Of
analysed,
1,380
severe.
Logistic
showed
that
age,
male
sex,
cardiovascular
disease,
cerebrovascular
chronic
lung
renal
failure
and/or
dialysis,
physician-diagnosed
obesity,
disease.
Vaccination
dementia
identified
as
associated
non-severe
illness.
ATT
was
−0.04
(95%
confidence
interval
−0.07
−0.01),
0.09
(0.06
0.12)
0.17
(0.14
0.19),
respectively.
Our
results
suggest
living
have
substantial
association
VOC,
while
may
be
Язык: Английский
COVID-19-related Health Outcomes during Delivery Hospitalization During Pre-delta, Delta, and Omicron Periods
Research Square (Research Square),
Год журнала:
2023,
Номер
unknown
Опубликована: Сен. 20, 2023
Abstract
Background
SARS-CoV-2
infection
during
pregnancy
has
been
associated
with
several
adverse
maternal
health
and
outcomes;
however,
few
studies
have
included
pregnancies
occurring
the
time
period
of
Omicron
variant
predominance
(January
2022–present)
in
evaluation
outcomes.
We
examined
relationship
between
COVID-19
diagnosis
at
delivery
outcomes
for
each
period,
a
focus
on
Omicron.
Methods
Data
hospitalizations
from
Premier
Healthcare
Database
February
2020
–August
2023
were
analyzed
as
cross-sectional
observational
study.
Adjusted
prevalence
ratios
(aPR)
calculated
to
compare
risks
women
without
period.
Results
Among
2,990,973
hospitalization,
1.9%
(n
=
56,618)
had
noted
discharge,
including
26,053
In
adjusted
models,
was
significant
increased
risk
sepsis
(COVID-19:
0.4%
vs
No
COVID-19:
0.1%)
(aPR:
3.32
[95%CI:
2.70,
4.08]),
acute
respiratory
distress
syndrome
(0.6%
(6.19
[5.26,
7.29]),
shock
(0.2%
(2.14
[1.62,
2.84]),
renal
failure
(0.5%
0.2%)
(2.08
[1.73,
2.49]),
ICU
admission
(2.7%
1.7%)
(1.64
[1.53,
1.77]),
mechanical
ventilation
(0.3%
(3.15
[2.52,
3.93]),
in-hospital
death
(0.0%
0.0%)(5.00
[2.30,
10.90]),
stillbirth
(0.7%
0.6%)
(1.17
[1.01,
1.36]),
preterm
birth
(12.3%
9.6%)
(1.34
[1.27,
1.42]).
Conclusions
During
remain
elevated,
despite
possibility
some
level
immunity
due
previous
SARS-COV-2
or
vaccination.
It
remains
important
pregnant
people,
those
planning
pregnancy,
stay
up
date
vaccination
reduce
Язык: Английский