E3S Web of Conferences,
Год журнала:
2024,
Номер
588, С. 02006 - 02006
Опубликована: Янв. 1, 2024
Gold
nanoparticles,
or
AuNPs,
have
garnered
significant
attention
in
biomedical
research,
especially
cancer
therapy,
due
to
their
unique
physicochemical
properties.
This
work
discusses
the
bioinspired
production
of
gold
nanoparticles
(AuNPs)
using
plant
extracts
as
reducing
and
stabilizing
agents.
research
conducted
synthesis.
Transmission
electron
microscopy
(TEM),
ultraviolet-visible
spectroscopy
(UV-Vis),
dynamic
light
scattering
(DLS),
Fourier
transform
infrared
(FTIR)
were
used
analyze
synthesized
nanoparticles.
These
approaches
characterize
nanoparticles’
dimensions,
morphology,
stability,
functional
groups.
At
a
wavelength
532
nm,
averaging
18
±
3
nm
size,
exhibited
pronounced
surface
plasmon
resonance
(SPR)
peak,
indicating
efficacy
manufacturing
method.
Cell
viability
assessments
performed
HeLa
(a
cervical
cell
type),
MCF-7
breast
model),
WI-38
healthy
fibroblast
model)
demonstrated
concentration-dependent
reduction
viability,
with
little
impact
on
cells.
concentration
100
µg/mL
cells
decreased
35.2%
41.7%,
respectively.
The
was
maintained
at
83.4%.
analysis
apoptosis
revealed
that
AuNPs
induced
early
late
rates
35.4%
45.8%,
respectively,
but
cells,
they
32.5%
42.1%.
therapeutic
significantly
enhanced
by
bioactive
compounds
isolated
from
plant.
eco-friendly
synthesis
method
this
study
not
only
provides
sustainable
means
for
nanoparticle
also
enhances
potential
application
anti-cancer
therapies.
applications
these
will
be
further
explored
via
vivo
tests,
which
emphasis
next
research.
Journal of Environmental Quality,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 3, 2025
Abstract
We
investigated
the
potential
toxic
effects
of
iron
oxide
magnetic
nanoparticles
(IOMNPs)
varied
size,
synthesized
through
biological
and
chemical
methods
on
freshwater
marine
microalgae
bacterial
species.
The
study
provides
insights
into
pollution
ecological
impacts
NPs.
IOMNPs
two
sizes,
20–50
nm
(quasi‐spherical)
using
a
cell‐free
fungal
extract
(biogenic
method),
104
(spherical)
obtained
from
commercial
source
(chemical
were
tested
for
aggregation,
bioavailability,
toxicity
at
multiple
concentrations
(12.5,
25,
50,
100,
125
µg
mL
−1
).
Microalgal
growth
media
(Bold's
basal
sea
salt
[SSM])
was
used
aggregation
analysis
dynamic
light
scattering
(DLS)
technique.
DLS
showed
similar
patterns
both
type
IOMNPs,
with
relatively
larger
aggregate
formation
in
SSM.
Toxicity
assessments
that
biogenic
smaller
size
non‐toxic,
while
large
(104
nm)
significantly
reduced
cell
density
microalgal
lipid
carotenoid
content
higher
concentrations.
Further,
transmission
electron
microscopy
X‐ray
fluorescence
confirmed
IOMNP
uptake
by
microalgae.
TEM
images
more
pronounced
structural
damage
caused
IOMNPs.
Our
findings
provide
crucial
differential
based
their
synthesis
key
aquatic
microorganisms
to
mitigate
issues
related
NP
pollution.
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(6), С. 2492 - 2492
Опубликована: Март 11, 2025
Nanoparticles
are
small
structures
that
differ
in
terms
of
their
shape
and
composition;
high
surface-to-volume
ratio
is
responsible
for
unique
properties
make
them
perfect
mediators
the
delivery
substances.
do
not
only
include
metallic
spheres
but
also
complex
polysaccharides
capsule
viruses
or
bacterial
protein
complexes
(which
can
be
considered
bionanoparticles),
which
1–100
nm
size.
Although
nanoparticles
most
widely
studied
from
medical
perspectives,
potential
applications
almost
limitless.
One
such
promising
use
functional
plant
protection
against
diseases.
precise
decreases
need
other
chemical
compounds,
thanks
to
increased
product
stability
a
target
site,
production
often
burdened
by
large
quantities
toxic
wastes.
This
problem
limited
if
we
apply
bioreactor
green
synthesis
method,
includes
with
microorganisms.
Bacteria
produce
internally,
externally,
producing
metabolites
used
nanoparticle
directly,
e.g.,
surfactants,
indirectly
as
reducing
agents
metal
production.
Regardless
source
nanoparticles,
they
processes
disease/pathogen
detection
disease
suppression.
The
endless
variety
materials
possible
modifications
subjected
makes
it
impossible
predict
how
will
future.
Nevertheless,
this
study,
would
like
turn
attention
fact
although
viewed
synthetic
structures,
ever-present
microbial
world
play
an
important
part
intermicrobial
interactions.
As
usefulness
has
been
tested
over
years
co-evolution,
may
useful
look
future
directions
fascinating
technology.
