Advanced biomaterials for targeting mature biofilms in periodontitis therapy

Bioactive Materials, Год журнала: 2025, Номер 48, С. 474 - 492

Опубликована: Фев. 27, 2025

Язык: Английский

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A self-supplied hydrogen peroxide and nitric oxide-generating nanoplatform enhances the efficacy of chemodynamic therapy for biofilm eradication

Journal of Colloid and Interface Science, Год журнала: 2024, Номер 678, С. 20 - 29

Опубликована: Авг. 22, 2024

Язык: Английский

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Interface/Dipole Polarized Antibiotics‐Loaded Fe₃O₄/PB Nanoparticles for Non‐Invasive Therapy of Osteomyelitis Under Medical Microwave Irradiation

Advanced Materials, Год журнала: 2024, Номер unknown

Опубликована: Сен. 30, 2024

Abstract Due to their poor light penetration, photothermal therapy and photodynamic are ineffective in treating deep tissue infections, such as osteomyelitis caused by Staphylococcus aureus ( S. ). Here, a microwave (MW)‐responsive magnetic targeting composite system consisting of ferric oxide (Fe 3 O 4 )/Prussian blue (PB) nanoparticles, gentamicin (Gent), biodegradable poly(lactic‐co‐glycolic acid) (PLGA) is reported. The PLGA/Fe /PB/Gent complex used combination with MW thermal (MTT), dynamic (MDT), chemotherapy (CT) treat acute infected ‐infected. powerful antibacterial effect the determined synergistic effects heat reactive oxygen species (ROS) generation Fe /PB nanoparticles under irradiation effective release Gent at infection site via targeting. mechanism analyzed using bacterial transcriptome RNA sequencing. ROS reduce activity protein transporters on membrane, along transport various ions acceleration phosphate metabolism, which can lead increased permeability damage ribosome DNA, accompany internal efflux bacteria, thus effectively killing bacteria.

Язык: Английский

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Dual-Action Defense: A photothermal and controlled nitric Oxide-Releasing coating for preventing biofilm formation

Journal of Colloid and Interface Science, Год журнала: 2024, Номер 679, С. 191 - 200

Опубликована: Окт. 20, 2024

Язык: Английский

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Melanin as a Photothermal Agent in Antimicrobial Systems

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(16), С. 8975 - 8975

Опубликована: Авг. 18, 2024

Bacterial infection is one of the most problematic issues for human health and resistance bacteria to traditional antibiotics a matter huge concern. Therefore, research focusing on development new strategies efficiently kill these microorganisms. Recently, melanin starting be investigated this purpose. Indeed, very versatile material presents outstanding photothermal properties, already studied therapy, which can useful light-induced eradication bacteria. In review, we present antibacterial applications based effect, both single action its combination with other systems. Melanin, also thanks biocompatibility ease functionalization, has been demonstrated easily applicable as an antimicrobial agent, especially treatment local infections.

Язык: Английский

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An injectable hydrogel containing versatile nanoparticles with antioxidant and antifibrotic properties for myocardial infarction treatment

Journal of Material Science and Technology, Год журнала: 2024, Номер 215, С. 121 - 130

Опубликована: Авг. 29, 2024

Язык: Английский

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Contactless and Biosafe Freshness Protection Package Consists of Geraniol@β-cyclodextrin MOF Complex for Emperor Banana Storage

ACS Food Science & Technology, Год журнала: 2024, Номер unknown

Опубликована: Окт. 27, 2024

Язык: Английский

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Novel nanomaterials-based combating strategies against drug-resistant bacteria

Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 248, С. 114478 - 114478

Опубликована: Дек. 28, 2024

Язык: Английский

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Multifunctional NIR-II Nanoplatform for Disrupting Biofilm and Promoting Infected Wound Healing

Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 245, С. 114330 - 114330

Опубликована: Окт. 23, 2024

Язык: Английский

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Bioinspired programmed antibiofilm strategies for accelerated wound healing via spatiotemporally controlled enzyme nanoreactors

Journal of Controlled Release, Год журнала: 2025, Номер unknown, С. 113582 - 113582

Опубликована: Март 1, 2025

Язык: Английский

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