Potential of ultrasound stimulation and sonogenetics in vision restoration: a narrative review DOI Creative Commons
Jie Ji, Chen Gong, Gengxi Lu

и другие.

Neural Regeneration Research, Год журнала: 2024, Номер 20(12), С. 3501 - 3516

Опубликована: Дек. 16, 2024

Vision restoration presents a considerable challenge in the realm of regenerative medicine, while recent progress ultrasound stimulation has displayed potential as non-invasive therapeutic approach. This narrative review offers comprehensive overview current research on ultrasound-stimulated neuromodulation, emphasizing its treatment modality for various nerve injuries. By examining efficacy different types modulating peripheral and optic nerves, we can delve into their underlying molecular mechanisms. Furthermore, underscores sonogenetics vision restoration, which involves leveraging pharmacological genetic manipulations to inhibit or enhance expression related mechanosensitive channels, thereby strength response. We also address how methods such viral transcription be utilized render specific neurons organs highly responsive ultrasound, leading significantly improved outcomes.

Язык: Английский

Animal Models for the Evaluation of Retinal Stem Cell Therapies DOI
Biju B. Thomas, Deepthi S. Rajendran Nair,

Mana Rahimian

и другие.

Progress in Retinal and Eye Research, Год журнала: 2025, Номер unknown, С. 101356 - 101356

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Potential of ultrasound stimulation and sonogenetics in vision restoration: a narrative review DOI Creative Commons
Jie Ji, Chen Gong, Gengxi Lu

и другие.

Neural Regeneration Research, Год журнала: 2024, Номер 20(12), С. 3501 - 3516

Опубликована: Дек. 16, 2024

Vision restoration presents a considerable challenge in the realm of regenerative medicine, while recent progress ultrasound stimulation has displayed potential as non-invasive therapeutic approach. This narrative review offers comprehensive overview current research on ultrasound-stimulated neuromodulation, emphasizing its treatment modality for various nerve injuries. By examining efficacy different types modulating peripheral and optic nerves, we can delve into their underlying molecular mechanisms. Furthermore, underscores sonogenetics vision restoration, which involves leveraging pharmacological genetic manipulations to inhibit or enhance expression related mechanosensitive channels, thereby strength response. We also address how methods such viral transcription be utilized render specific neurons organs highly responsive ultrasound, leading significantly improved outcomes.

Язык: Английский

Процитировано

0