Seminars in Thrombosis and Hemostasis

Seminars in Thrombosis and Hemostasis, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 5, 2024

Язык: Английский

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Four years into the pandemic, managing COVID-19 patients with acute coagulopathy: what have we learned?

Journal of Thrombosis and Haemostasis, Год журнала: 2024, Номер 22(6), С. 1541 - 1549

Опубликована: Фев. 29, 2024

Язык: Английский

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Temporal Trends in Pulmonary Embolism Mortality Associated with COVID-19 in the United States: A 5-Year Retrospective Analysis

International Journal of Angiology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 24, 2025

Abstract Coronavirus disease 2019 (COVID-19) has been strongly associated with thrombotic complications, particularly pulmonary embolism (PE). This study aims to analyze the real-world impact of COVID-19 on PE-related mortality in United States over first 5 years pandemic. We conducted a retrospective observational using CDC WONDER database, combining data from PE and 10th revision International Classification Diseases (ICD-10) codes I26 (PE) U07.1 (COVID-19). The analysis spanned 2020 2024. found peak COVID-19-associated deaths 2021, an estimated crude rate 211 × 1,000 deaths. progressively declined following years, being 141 2022, 44 2023, 29 2024, respectively. for was 111 throughout 5-year period. results our show that may have contributed nearly one-tenth all Despite gradual decline since its still sustained suggests ongoing risks, especially impacting high-risk populations, emphasizing need continued vigilance prevention complications patients.

Язык: Английский

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Predictors of venous thromboembolic events in hospitalized patients with COVID-19

Journal of Thrombosis and Thrombolysis, Год журнала: 2025, Номер unknown

Опубликована: Март 10, 2025

Язык: Английский

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S-hydroxychloroquine prevents the antiphospholipid thrombogenic complexes for antiphospholipid syndrome treatment

Biomedicine & Pharmacotherapy, Год журнала: 2025, Номер 186, С. 117968 - 117968

Опубликована: Март 23, 2025

Язык: Английский

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Catastrophic Thrombosis: A Narrative Review

Seminars in Thrombosis and Hemostasis, Год журнала: 2024, Номер unknown

Опубликована: Авг. 16, 2024

Abstract Catastrophic thrombosis is a severe condition characterized by hypercoagulable tendency, leading to multiple thromboembolic events in different blood vessels, usually within short timeframe. Several conditions have been associated with the development of catastrophic thrombosis, including antiphospholipid syndrome, thrombotic anti-platelet factor 4 immune disorders, microangiopathies, cancers, hyper-eosinophilic pregnancy, infections, trauma, and drugs. Thrombotic storm represents medical emergency whose management serious challenge for physicians. Besides prompt start anticoagulation, patient's prognosis depends on early recognition possible treatment underlying condition. In this narrative review, we summarize main characteristics analyzing various triggering such life-threatening complication. Finally, an algorithm diagnostic workup initial patients presented.

Язык: Английский

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“2023 ISTH update of the 2022 ISTH guidelines for antithrombotic treatment in COVID-19”: comment from Flumignan et al.

Journal of Thrombosis and Haemostasis, Год журнала: 2024, Номер 22(9), С. 2670 - 2671

Опубликована: Авг. 23, 2024

Язык: Английский

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Venous Thromboembolism Prevention in the Hospitalized Medical Patient

Medical Clinics of North America, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

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The Basic Principles of Pathophysiology of Venous Thrombosis

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(21), С. 11447 - 11447

Опубликована: Окт. 24, 2024

The past few decades have brought tremendous insight into the molecular and pathophysiological mechanisms responsible for thrombus generation. For a clinician, it is usually sufficient to explain incident of deep vein thrombosis (DVT) with provoking factors such as trauma vascular injury, immobilization, hormonal factors, or inherited acquired coagulation defects. About half DVTs are, however, lacking triggers are called unprovoked. Venous stasis hypoxia at valve sinus level may start chain reactions. concept immunothrombosis has added new dimension old etiological triad venous stasis, vessel wall changes in blood components. This particularly important COVID-19, where hyperinflammation, cytokines, neutrophil extracellular traps associated formation microthrombi lungs. To better understand behind DVT reach beyond above-mentioned simplifications, animal models clinical epidemiological studies complex interplay between leukocytes, platelets, endothelium, complements, inhibitors. These pathways will be reviewed here, well roles cancer, anticancer drugs, congenital thrombophilic defects on hypercoagulability thromboembolism.

Язык: Английский

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Recent Advances in Thrombosis and Hemostasis—Part X

Seminars in Thrombosis and Hemostasis, Год журнала: 2024, Номер 50(06), С. 807 - 808

Опубликована: Май 11, 2024

Some people worry that artificial intelligence will make us feel inferior, but then, anybody in his right mind should have an inferiority complex every time he looks at a flower.—

Язык: Английский

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