Baseline comorbidity of cardiovascular-kidney-metabolic syndrome increases the risk of adverse clinical outcomes in patients with chronic kidney disease DOI Creative Commons

Jiali Meng,

Wen Li,

Wenjing Fu

и другие.

Frontiers in Endocrinology, Год журнала: 2025, Номер 16

Опубликована: Апрель 16, 2025

Our study aims to analyze the relationship between different stage of Cardiovascular-Kidney-Metabolic (CKM) Syndrome in Chronic Kidney Disease (CKD) patients and risk progression all-caused mortality or end-stage renal disease (ESRD). A retrospective cohort was performed by collecting baseline data CKD patients. All participants were followed throughout course study. Cox proportional hazards analysis Fine-Gray subdistribution model prognostic value CKM stages on adverse clinical outcomes (all-caused ESRD) these 1,358 finally completed follow-up. Among them, 1,233 alive, 125 had died; 163 progressed ESRD. Baseline 3 (OR=3.906, 95% CI=0.988-16.320, p=0.048) 4 (OR=5.728, CI=1.329-24.698, p=0.019) remain independent factors for all-cause patients, while 2b (OR=2.739, CI=1.157-6.486, p=0.022) identified as having an factor ESRD adjusting confounding factors. research demonstrated that a high-risk can predict including

Язык: Английский

Baseline comorbidity of cardiovascular-kidney-metabolic syndrome increases the risk of adverse clinical outcomes in patients with chronic kidney disease DOI Creative Commons

Jiali Meng,

Wen Li,

Wenjing Fu

и другие.

Frontiers in Endocrinology, Год журнала: 2025, Номер 16

Опубликована: Апрель 16, 2025

Our study aims to analyze the relationship between different stage of Cardiovascular-Kidney-Metabolic (CKM) Syndrome in Chronic Kidney Disease (CKD) patients and risk progression all-caused mortality or end-stage renal disease (ESRD). A retrospective cohort was performed by collecting baseline data CKD patients. All participants were followed throughout course study. Cox proportional hazards analysis Fine-Gray subdistribution model prognostic value CKM stages on adverse clinical outcomes (all-caused ESRD) these 1,358 finally completed follow-up. Among them, 1,233 alive, 125 had died; 163 progressed ESRD. Baseline 3 (OR=3.906, 95% CI=0.988-16.320, p=0.048) 4 (OR=5.728, CI=1.329-24.698, p=0.019) remain independent factors for all-cause patients, while 2b (OR=2.739, CI=1.157-6.486, p=0.022) identified as having an factor ESRD adjusting confounding factors. research demonstrated that a high-risk can predict including

Язык: Английский

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