Baseline comorbidity of cardiovascular-kidney-metabolic syndrome increases the risk of adverse clinical outcomes in patients with chronic kidney disease DOI Creative Commons

Jiali Meng,

Wen Li,

Wenjing Fu

et al.

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: April 16, 2025

Our study aims to analyze the relationship between different stage of Cardiovascular-Kidney-Metabolic (CKM) Syndrome in Chronic Kidney Disease (CKD) patients and risk progression all-caused mortality or end-stage renal disease (ESRD). A retrospective cohort was performed by collecting baseline data CKD patients. All participants were followed throughout course study. Cox proportional hazards analysis Fine-Gray subdistribution model prognostic value CKM stages on adverse clinical outcomes (all-caused ESRD) these 1,358 finally completed follow-up. Among them, 1,233 alive, 125 had died; 163 progressed ESRD. Baseline 3 (OR=3.906, 95% CI=0.988-16.320, p=0.048) 4 (OR=5.728, CI=1.329-24.698, p=0.019) remain independent factors for all-cause patients, while 2b (OR=2.739, CI=1.157-6.486, p=0.022) identified as having an factor ESRD adjusting confounding factors. research demonstrated that a high-risk can predict including

Language: Английский

Baseline comorbidity of cardiovascular-kidney-metabolic syndrome increases the risk of adverse clinical outcomes in patients with chronic kidney disease DOI Creative Commons

Jiali Meng,

Wen Li,

Wenjing Fu

et al.

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: April 16, 2025

Our study aims to analyze the relationship between different stage of Cardiovascular-Kidney-Metabolic (CKM) Syndrome in Chronic Kidney Disease (CKD) patients and risk progression all-caused mortality or end-stage renal disease (ESRD). A retrospective cohort was performed by collecting baseline data CKD patients. All participants were followed throughout course study. Cox proportional hazards analysis Fine-Gray subdistribution model prognostic value CKM stages on adverse clinical outcomes (all-caused ESRD) these 1,358 finally completed follow-up. Among them, 1,233 alive, 125 had died; 163 progressed ESRD. Baseline 3 (OR=3.906, 95% CI=0.988-16.320, p=0.048) 4 (OR=5.728, CI=1.329-24.698, p=0.019) remain independent factors for all-cause patients, while 2b (OR=2.739, CI=1.157-6.486, p=0.022) identified as having an factor ESRD adjusting confounding factors. research demonstrated that a high-risk can predict including

Language: Английский

Citations

0