Stress, epigenetics, and aging: Unraveling the intricate crosstalk
Molecular Cell,
Год журнала:
2023,
Номер
84(1), С. 34 - 54
Опубликована: Ноя. 13, 2023
Язык: Английский
Vaginal microbiota transplantation is a truly opulent and promising edge: fully grasp its potential
Frontiers in Cellular and Infection Microbiology,
Год журнала:
2024,
Номер
14
Опубликована: Март 22, 2024
Vaginal
microbiota
transplantation
(VMT)
is
a
cutting-edge
treatment
modality
that
has
the
potential
to
revolutionize
management
of
vaginal
disorders.
The
human
vagina
complex
and
dynamic
ecosystem
home
diverse
community
microorganisms.
These
microorganisms
play
crucial
role
in
maintaining
health
well-being
female
reproductive
system.
However,
when
balance
this
disrupted,
it
can
lead
development
various
Conventional
treatments,
such
as
antibiotics
antifungal
medications,
temporarily
relieve
symptoms
they
often
fail
address
underlying
cause
problem,
which
disruption
microbiota.
In
recent
years,
VMT
emerged
promising
therapeutic
approach
aims
restore
ecosystem.
Several
studies
have
demonstrated
safety
efficacy
treating
bacterial
vaginosis,
recurrent
yeast
infections,
other
conditions.
procedure
also
shown
results
reducing
risk
sexually
transmitted
infections
preterm
birth
pregnant
women.
more
research
needed
establish
optimal
donor
selection,
preparation,
screening
protocols,
well
long-term
efficacy.
offers
safe,
effective,
minimally
invasive
option
for
women
with
persistent
problems.
It
could
improve
quality
life
millions
worldwide
become
standard
shortly.
With
further
development,
potentially
treat
wide
range
problems
beyond
scope
Язык: Английский
Pick fecal microbiota transplantation to enhance therapy for major depressive disorder
Progress in Neuro-Psychopharmacology and Biological Psychiatry,
Год журнала:
2023,
Номер
128, С. 110860 - 110860
Опубликована: Сен. 9, 2023
Язык: Английский
A viable remedy for overcoming resistance to anti-PD-1 immunotherapy: Fecal microbiota transplantation
Critical Reviews in Oncology/Hematology,
Год журнала:
2024,
Номер
200, С. 104403 - 104403
Опубликована: Июнь 4, 2024
Язык: Английский
Game changer: Navigating between challenges and hopes in geropharmacology
Qian Chen,
Robert A. Hartman,
Lidia Dankiv
и другие.
Advances in pharmacology,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Язык: Английский
SuperAgers and centenarians, dynamics of healthy ageing with cognitive resilience
Mechanisms of Ageing and Development,
Год журнала:
2024,
Номер
219, С. 111936 - 111936
Опубликована: Апрель 22, 2024
Язык: Английский
Gut Microbiota and (Neuro)Inflammation: Involvement of Endotoxin in the Pathogenesis of Endogenous Psychoses
Psikhiatriya,
Год журнала:
2023,
Номер
21(5), С. 86 - 96
Опубликована: Окт. 24, 2023
Background:
there
is
a
two-way
relationship
between
the
gut
microbiota
(GM)
and
brain,
both
in
normal
pathological
conditions.
It
has
been
suggested
that
disturbances
GM
composition
function
can
lead
to
activation
of
(neuro)
inflammation
or
its
maintenance
mental
disorders.
Objective:
analysis
scientific
publications,
including
results
our
own
research
on
microbiota,
role
modulation
brain
functions
involvement
(neuro)inflammation
endogenous
Material
method:
using
keywords
“gut–microbiota”
“microbiota–gut–brain
axis/mental
disorders”,
“inflammation”,
“neuroinflammation”,
articles
reviews
were
searched
databases
electronic
libraries
publications
Medline/PubMed,
Scopus,
Google
Scholar,
RSCI,
other
sources.
Results:
basis
literature
sources,
general
information
about
GM,
composition,
main
ways
interaction
with
given.
The
development
(neuro)inflammation,
currently
considered
as
one
pathogenetic
mechanisms
disorders,
discussed.
Particular
attention
paid
studies
endotoxin
(ET)
(lipopolysaccharide
—
LPS)
psychoses
these
indicators
effectiveness
pharmacotherapy.
Conclusion:
it
established
an
important
participant
regulator
neuro-immune
interactions.
possible
disorders
participation
aggression
(EA)
formation
therapeutic
resistance
revealed.
Язык: Английский
Unlock the power of bovine milk-derived exosomes for degenerative diseases associated with aging
Journal of Functional Foods,
Год журнала:
2023,
Номер
109, С. 105788 - 105788
Опубликована: Сен. 15, 2023
Bovine
milk-derived
exosomes
(BMDEs)
have
emerged
as
a
fruitful
area
of
investigation
in
age-related
disease
therapeutics.
Through
the
utilization
BMDEs,
researchers
possess
capacity
to
unveil
novel
treatments
and
therapeutic
interventions
that
potential
enhance
quality
life
for
elderly
individuals
across
globe.
Studies
provided
evidence
efficacy
BMDEs
facilitating
regenerative
processes
bone
cartilage,
thus
establishing
their
viable
avenue
addressing
conditions
like
osteoarthritis.
Although
show
promise
prospective
research
route
tackling
illnesses,
including
Parkinson's
disease,
osteoporosis,
skin
rejuvenation,
other
unanswered
questions
still
demand
more
exploration.
Concerns
been
raised
regarding
safety
especially
human
administration,
must
carefully
examine
these
concerns
identify
alternatives.
In
conclusion,
are
an
ripe
into
prevention
treatment
diseases.
Язык: Английский