Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Авг. 15, 2024
Chitosan
(CS)
has
been
extensively
studied
in
wound
care
for
its
intrinsic
hemostatic
and
antibacterial
properties.
However,
CS
limiting
hemostasis
applications
on
account
of
drawbacks
such
as
poor
adhesion
humid
environments
water
solubility
at
neutral
pH.
CS-based
biomaterials,
inspired
by
mussel-adhesive
proteins,
serve
a
suggested
platform
biomedical
science.
The
reports
show
that
the
mussel-inspired
structure
negligible
toxicity
excellent
adhesiveness.
Biomedicine
witnessed
significant
progress
development
these
materials.
This
review
summarizes
methods
modification
chemistry.
Moreover,
general
method
preparation
biomaterials
is
briefly
discussed
this
review.
work
expected
to
give
better
understanding
opportunities
challenges
strategy
functionalization
healing.
hoped
provide
an
important
perspective
Chemical Engineering Journal,
Год журнала:
2024,
Номер
481, С. 148674 - 148674
Опубликована: Янв. 11, 2024
Multi-resistant
pathogens
can
cause
several
nosocomial
infections
that
harm
hospital
interventions
or
undermine
biological
processes.
In
this
scenario,
the
development
of
novel
and
efficient
antimicrobial
materials
is
essential
to
reducing
pathogen
spread.
Though
many
approaches
have
been
followed
with
aim,
scalability,
safety,
efficiency
concerns
still
hamper
their
clinical
transfer.
work,
we
overcome
these
limitations
by
co-polymerizing
phenolic
derivatives
amino-terminal
ligands.
The
resulting
coatings
are
successfully
applied
woven
non-woven-based
used
in
healthcare:
paper,
cotton
polypropylene.
Moreover,
demonstrate
multi-pathway
activity
against
six
bacteria
(E.
coli,
P.
aeruginosa,
S.
aureus,
methicillin-resistant
E.
faecalis,
B.
subtilis)
two
fungi
(C.
albicans
C.
auris),
a
fact
attributed
i)
reactive
oxygen
species
generation
over
time
ii)
protic
amino
groups
exposed
on
surface.
After
180
min,
viable
reduced
more
than
99.9
%,
comparable
decline
after
24
h.
As
proof-of-concept,
coated
commercial
band-aids
tested
skin
ex
vivo
bacterial
growth
about
90
%.
Considering
results
long-lasting,
vitro
biocompatibility,
scalability
eco-friendly
technology,
represent
promising
alternative
be
healthcare
environments,
avoiding
spread,
resistance.
Biomacromolecules,
Год журнала:
2024,
Номер
25(4), С. 2438 - 2448
Опубликована: Март 19, 2024
The
treatment
of
infected
wounds
faces
substantial
challenges
due
to
the
high
incidence
and
serious
infection-related
complications.
Natural-based
hydrogel
dressings
with
favorable
antibacterial
properties
strong
applicability
are
urgently
needed.
Herein,
we
developed
a
composite
by
constructing
multiple
networks
loading
ciprofloxacin
for
wound
healing.
was
synthesized
via
Schiff
base
reaction
between
carboxymethyl
chitosan
oxidized
sodium
alginate,
followed
polymerization
acrylamide
monomer.
resultant
dressing
possessed
good
self-healing
ability,
considerable
compression
strength,
reliable
fatigue
resistance.
In
vitro
assessment
showed
that
effectively
eliminated
bacteria
exhibited
an
excellent
biocompatibility.
model
Advanced Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 11, 2024
Abstract
The
main
features
of
early
caries
are
the
massive
colonization
cariogenic
bacteria
and
demineralization
tooth
enamel
by
acids
that
they
produce.
Owing
to
lack
effective
treatments,
development
anticaries
therapeutics
with
both
antimicrobial
remineralizing
properties
is
urgently
required.
Black
phosphorus
nanosheets
(BPNs)
ideal
for
treatment
because
can
mediate
photothermal
antibacterial
activity
subsequently
promote
remineralization
generating
PO
4
3−
.
However,
dynamic
wet
environment
oral
cavity
prevents
long‐term
adhesion
BPNs
surface.
In
this
study,
using
catechol‐modified
chitosan
PLGA‐PEG‐PLGA
as
raw
materials,
a
mussel‐inspired
versatile
hydrogel,
BP@CP5,
presented
be
used
physically
load
BPNs.
BP@CP5
has
exceptional
injectability
firmly
adhere
surfaces
up
24
h.
Upon
irradiation,
quickly
eliminate
≈99%
Streptococcus
mutans
sanguinis
;
furthermore,
generated
via
degradation
also
promotes
rapid
slabs.
Importantly,
vivo
rodent
modeling
results
further
confirm
excellent
caries‐prevention
BP@CP5.
This
study
demonstrates
promising
material
management.
Frontiers in Nanotechnology,
Год журнала:
2024,
Номер
6
Опубликована: Март 27, 2024
The
increase
in
global
population
has
had
a
tremendous
impact
on
sustainable
agri-food
practices.
With
the
growth
world
population,
various
modern
technologies
are
being
utilized
that
more
often
result
opening
of
opportunities
agriculture
and
food
sectors.
Nanotechnology
is
used
sectors
for
variety
purposes,
including
enhancing
flavor,
pest/pathogen
diagnosis,
production,
processing,
storage,
packaging,
transportation
agricultural
products.
Plant
pathogenic
microorganisms
bacteria,
viruses,
fungi,
nematodes
have
significant
economy.
In
particular,
advances
nanotechnology,
nanobiosensors,
been
detection
plant
diseases
pathogens,
evaluation
examination
infections
caused
by
microorganisms,
management
and,
thus,
promotion
security.
Apart
from
diseases,
nanobiosensors
offer
better
production
controlling
physical,
chemical,
biological
processes,
thus
improving
safety
This
review
outlines
application
nano-integrated
