3D Printing and Electrospinning of Drug- and Graphene-Enhanced Polycaprolactone Scaffolds for Osteochondral Nasal Repair

Materials, Год журнала: 2025, Номер 18(8), С. 1826 - 1826

Опубликована: Апрель 16, 2025

A novel bi-layered scaffold, obtained via 3D printing and electrospinning, was designed to improve osteochondral region reconstruction. The upper electrospun membrane will act as a barrier against unwanted tissue infiltration, while the lower 3D-printed layer provide porous structure for ingrowth. Graphene integrated into scaffold its antibacterial properties, drug Osteogenon® (OST) added promote bone regeneration. composite scaffolds were subjected comprehensive physical, thermal, mechanical evaluations. Additionally, their biological functionality assessed by means of NHAC-kn cells. 0.5% graphene addition PCL significantly increased strain at break, enhancing material ductility. GNP also acted an effective nucleating agent, raising crystallization temperatures supporting mineralization. high surface area facilitated rapid apatite formation attracting calcium phosphate ions. This confirmed FTIR, µCT SEM analyses, which highlighted positive impact on mineral deposition. synergistic interaction between nanoplatelets created bioactive environment that enhanced cell adhesion proliferation, promoted superior formation. These findings highlight scaffold’s potential promising biomaterial repair regenerative medicine.

Язык: Английский

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Advances in the Research of Mesenchymal Stromal Cells in the Treatment of Maxillofacial Neurological Disorders and the Promotion of Facial Nerve Regeneration

Molecular Neurobiology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 28, 2025

Язык: Английский

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Modern methods and technology in periodontal treatment: a review article

International Journal of Community Medicine and Public Health, Год журнала: 2025, Номер 12(5), С. 2374 - 2382

Опубликована: Апрель 30, 2025

Periodontal treatment has evolved significantly due to technological advancements and novel methodologies. Between 2020 2024, integrating digital technologies, therapeutic innovations, advanced modalities transformed clinical practice, improving patient outcomes. This review examines recent developments in periodontal care, focusing on methodologies such as laser therapy, guided tissue regeneration (GTR), imaging. Key technologies analyzed include antimicrobial photodynamic therapy (aPDT), cone-beam computed tomography (CBCT), computer-aided design/manufacturing (CAD/CAM), 3D bioprinting. The integration of these enhanced the diagnostic, therapeutic, prognostic capabilities practitioners. Additionally, biomaterials engineering have shown promise regenerative supporting natural healing minimizing invasive surgical interventions. Modern improved efficacy care. highlights evolution techniques, assessing their benefits limitations contemporary practice.

Язык: Английский

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Advancements in GelMA/ceramic composites for dental applications: integration with portable 4D bioprinting technologies

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 143993 - 143993

Опубликована: Май 1, 2025

Язык: Английский

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Silk as a promising biomaterial for 3D bioprinting: a comprehensive review of Bombyx mori silk’s biomedical applications

International Journal of Polymeric Materials, Год журнала: 2024, Номер unknown, С. 1 - 17

Опубликована: Апрель 25, 2024

This comprehensive review discusses the exceptional mechanical and biological properties of Bombyx mori silkworm's silk fibroin (SF) its potential for biomedical applications. It focuses on recent interest in using SF 3D bioprinting tissue engineering provides an overview advancements this area. The covers topics such as fabrication techniques, SF-based bioinks, scaffold design, applications fields like bone, cartilage, skin, nerve, vascular regeneration. also addresses future challenges directions, including improving printing resolution developing new silk-based biomaterials or their combination with other hydrogels.

Язык: Английский

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4D printing of biological macromolecules employing handheld bioprinters for in situ wound healing applications

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 280, С. 135999 - 135999

Опубликована: Сен. 24, 2024

Язык: Английский

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Biofabrication: Bioprinting Process, Printing Materials, and the Frontier Applications in Biomedicine

Deleted Journal, Год журнала: 2024, Номер unknown, С. 200175 - 200175

Опубликована: Окт. 1, 2024

Язык: Английский

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Mechanism of liquid jetting by driving jet tube for reciprocating motion

Physics of Fluids, Год журнала: 2024, Номер 36(12)

Опубликована: Дек. 1, 2024

The reciprocating motion of a jet tube along its axial direction enables on-demand jetting, which is novel method. However, related research limited, and the jetting mechanism has not been thoroughly explained. In this study, piezoelectric ceramic used to drive in achieve jetting. Based on experimental simulation results, process described analyzed, revealed effects various factors are discussed. results show that inertial force caused by abrupt changes velocity main driving for at both ends stroke dominate process. During down-then-up tube, pushes liquid inside downwards form then pulls upward, causing tail break, achieving Changes level height amplitude affect influencing magnitude force, while period impacts time interval pushing pulling as well superposition pressure waves. When follows an up-then-down pattern, kinetic energy gained during smaller, making pattern less favorable

Язык: Английский

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Technique of 3D printing for scaffolding in tissue engineering of bones: Opportunities and challenges

Materials Today Communications, Год журнала: 2024, Номер 42, С. 111249 - 111249

Опубликована: Дек. 9, 2024

Язык: Английский

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Synergizing additive manufacturing and machine learning for advanced hydroxyapatite scaffold design in bone regeneration

Journal of the Australian Ceramic Society, Год журнала: 2024, Номер unknown

Опубликована: Авг. 26, 2024

Язык: Английский

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