Nature Nanotechnology, Год журнала: 2024, Номер 19(8), С. 1158 - 1167
Опубликована: Апрель 29, 2024
Язык: Английский
Nature Nanotechnology, Год журнала: 2024, Номер 19(8), С. 1158 - 1167
Опубликована: Апрель 29, 2024
Язык: Английский
ACS Nano, Год журнала: 2023, Номер 17(6), С. 5211 - 5295
Опубликована: Март 9, 2023
Humans rely increasingly on sensors to address grand challenges and improve quality of life in the era digitalization big data. For ubiquitous sensing, flexible are developed overcome limitations conventional rigid counterparts. Despite rapid advancement bench-side research over last decade, market adoption remains limited. To ease expedite their deployment, here, we identify bottlenecks hindering maturation propose promising solutions. We first analyze achieving satisfactory sensing performance for real-world applications then summarize issues compatible sensor-biology interfaces, followed by brief discussions powering connecting sensor networks. Issues en route commercialization sustainable growth sector also analyzed, highlighting environmental concerns emphasizing nontechnical such as business, regulatory, ethical considerations. Additionally, look at future intelligent sensors. In proposing a comprehensive roadmap, hope steer efforts towards common goals guide coordinated development strategies from disparate communities. Through collaborative efforts, scientific breakthroughs can be made sooner capitalized betterment humanity.
Язык: Английский
Процитировано
729Advanced Materials, Год журнала: 2022, Номер 35(1)
Опубликована: Окт. 21, 2022
On-skin electronics that offer revolutionary capabilities in personalized diagnosis, therapeutics, and human-machine interfaces require seamless integration between the skin electronics. A common question remains whether an ideal interface can be introduced to directly bridge thin-film with soft skin, allowing breathe freely skin-integrated function stably. Here, ever-thinnest hydrogel is reported compliant glyphic lines subtle minutiae on without forming air gaps, produced by a facile cold-lamination method. The hydrogels exhibit high water-vapor permeability, nearly unimpeded transepidermal water loss free breathing of underneath. Hydrogel-interfaced flexible (opto)electronics causing irritation or accelerated device performance deterioration are demonstrated. long-term applicability recorded for over one week. With combined features extreme mechanical compliance, biocompatibility, ultrathin promotes general
Язык: Английский
Процитировано
175Carbon, Год журнала: 2022, Номер 202, С. 495 - 527
Опубликована: Ноя. 9, 2022
Язык: Английский
Процитировано
146ACS Nano, Год журнала: 2023, Номер 17(11), С. 9681 - 9693
Опубликована: Май 18, 2023
Hydrogels have emerged as promising materials for flexible electronics due to their unique properties, such high water content, softness, and biocompatibility. In this perspective, we provide an overview of the development hydrogels electronics, with a focus on three key aspects: mechanical interfacial adhesion, conductivity. We discuss principles designing high-performance present representative examples potential applications in field healthcare. Despite significant progress, several challenges remain, including improving antifatigue capability, enhancing balancing content wet environments. Additionally, highlight importance considering hydrogel-cell interactions dynamic properties future research. Looking ahead, is promising, exciting opportunities horizon, but continued investment research necessary overcome remaining challenges.
Язык: Английский
Процитировано
141Science, Год журнала: 2023, Номер 381(6658), С. 686 - 693
Опубликована: Авг. 10, 2023
The use of bioelectronic devices relies on direct contact with soft biotissues. For transistor-type devices, the semiconductors that need to have interfacing biotissues for effective signal transduction do not adhere well wet tissues, thereby limiting stability and conformability at interface. We report a bioadhesive polymer semiconductor through double-network structure formed by brush redox-active semiconducting polymer. resulting film can form rapid strong adhesion tissue surfaces together high charge-carrier mobility ~1 square centimeter per volt second, stretchability, good biocompatibility. Further fabrication fully transistor sensor enabled us produce high-quality stable electrophysiological recordings an isolated rat heart in vivo muscles.
Язык: Английский
Процитировано
117Nature, Год журнала: 2023, Номер 624(7991), С. 295 - 302
Опубликована: Дек. 13, 2023
Язык: Английский
Процитировано
110Small Methods, Год журнала: 2023, Номер 7(2)
Опубликована: Янв. 8, 2023
Abstract Traditional public health systems suffer from incomprehensive, delayed, and inefficient medical services. Convenient comprehensive monitoring has been highly sought after recently. Flexible wearable devices are attracting wide attention due to their potential applications in human care systems. Using carbon materials with overall superiorities can facilitate the development of flexible various functions excellent performance, which comprehensively real‐time monitor status prevent diseases. Herein, latest advances rational design controlled fabrication for health‐related electronics reviewed. The strategies, working mechanism, carbon‐based devices, including electromechanical sensors, temperature/humidity chemical conductive wires/electrodes, Furthermore, integrating multiple into multifunctional is discussed. Finally, existing challenges future opportunities this field also proposed.
Язык: Английский
Процитировано
97Science Advances, Год журнала: 2023, Номер 9(22)
Опубликована: Май 31, 2023
Implantable bioelectronics provide unprecedented opportunities for real-time and continuous monitoring of physiological signals living bodies. Most adopt thin-film substrates such as polyimide polydimethylsiloxane that exhibit high levels flexibility stretchability. However, the low permeability relatively modulus these thin films hamper long-term biocompatibility. In contrast, devices fabricated on porous show advantages but suffer from patterning density. Here, we report a wafer-scale patternable strategy high-resolution fabrication supersoft, stretchable, permeable liquid metal microelectrodes (μLMEs). We demonstrate 2-μm capability, or an ultrahigh density ~75,500 electrodes/cm
Язык: Английский
Процитировано
87Advanced Materials, Год журнала: 2024, Номер 36(31)
Опубликована: Март 29, 2024
Wearable epidermic electronics assembled from conductive hydrogels are attracting various research attention for their seamless integration with human body conformally real-time health monitoring, clinical diagnostics and medical treatment, human-interactive sensing. Nevertheless, it remains a tremendous challenge to simultaneously achieve bioadhesive remarkable self-adhesiveness, reliable ultraviolet (UV) protection ability, admirable sensing performance high-fidelity epidermal electrophysiological signals along timely photothermal therapeutic performances after diagnostic sensing, as well efficient antibacterial activity hemostatic effect potential therapy. Herein, hydrogel-based sensor, featuring superior self-adhesiveness excellent UV-protection performance, is developed by dexterously assembling conducting MXene nanosheets network biological hydrogel polymer stably attaching onto skin high-quality recording of high signal-to-noise ratios (SNR) low interfacial impedance intelligent diagnosis smart human-machine interface. Moreover, sign language gesture recognition platform based on collected electromyogram (EMG) designed hassle-free communication hearing-impaired people the help advanced machine learning algorithms. Meanwhile, possesses capability, biocompatibility, effective hemostasis properties promising bacterial-infected wound bleeding.
Язык: Английский
Процитировано
86Nature Communications, Год журнала: 2023, Номер 14(1)
Опубликована: Июль 26, 2023
Abstract Soft and stretchable electronics have emerged as highly promising tools for biomedical diagnosis biological studies, they interface intimately with the human body other systems. Most electronic materials devices, however, still Young’s moduli orders of magnitude higher than soft bio-tissues, which limit their conformability long-term biocompatibility. Here, we present a design strategy interlayer allowing use existing relatively high to versatilely realize devices ultralow tissue-level moduli. We demonstrated transistor arrays active-matrix circuits below 10 kPa—over two lower current state art. Benefiting from increased irregular dynamic surfaces, ultrasoft device created realizes electrophysiological recording on an isolated heart adaptability, spatial stability, minimal influence ventricle pressure. In vivo biocompatibility tests also demonstrate benefit suppressing foreign-body responses implantation. With its general applicability diverse this soft-interlayer overcomes material-level limitation imparting softness variety bioelectronic devices.
Язык: Английский
Процитировано
82