Materials Today, Год журнала: 2024, Номер 75, С. 166 - 186
Опубликована: Апрель 7, 2024
Язык: Английский
Chemical Reviews, Год журнала: 2024, Номер 124(2), С. 455 - 553
Опубликована: Янв. 4, 2024
In the era of Internet-of-things, many things can stay connected; however, biological systems, including those necessary for human health, remain unable to connected global Internet due lack soft conformal biosensors. The fundamental challenge lies in fact that electronics and biology are distinct incompatible, as they based on different materials via functioning principles. particular, body is curvilinear, yet typically rigid planar. Recent advances design have generated tremendous opportunities wearable bioelectronics, which may bridge gap, enabling ultimate dream healthcare anyone, anytime, anywhere. We begin with a review historical development healthcare, indicating significant trend healthcare. This followed by focal point discussion about new design, particularly low-dimensional nanomaterials. summarize material types their attributes designing bioelectronic sensors; we also cover synthesis fabrication methods, top-down, bottom-up, combined approaches. Next, discuss energy challenges progress made date. addition front-end devices, describe back-end machine learning algorithms, artificial intelligence, telecommunication, software. Afterward, integration systems been applied various testbeds real-world settings, laboratories preclinical clinical environments. Finally, narrate remaining conjunction our perspectives.
Язык: Английский
Процитировано
155
Nature Reviews Bioengineering, Год журнала: 2024, Номер 2(8), С. 671 - 690
Опубликована: Июнь 17, 2024
Язык: Английский
Процитировано
91
Nature Reviews Materials, Год журнала: 2023, Номер 9(2), С. 134 - 149
Опубликована: Дек. 22, 2023
Язык: Английский
Процитировано
70
Nature Communications, Год журнала: 2024, Номер 15(1)
Опубликована: Янв. 30, 2024
Abstract Robust interfacial compliance is essential for long-term physiological monitoring via skin-mountable ionic materials. Unfortunately, existing epidermal skins are not compliant and durable enough to accommodate the time-varying deformations of convoluted skin surface, due an imbalance in viscosity elasticity. Here we introduce a self-compliant that consistently works at critical gel point state with almost equal elasticity over super-wide frequency range. The material designed by leveraging hierarchical hydrogen bond association, allowing continuous release polymer strands create topological entanglements as complementary crosslinks. By embodying properties rapid stress relaxation, softness, conductivity, self-healability, flaw-insensitivity, self-adhesion, water-resistance, this fosters excellent cyclically deforming substrates, facilitates acquisition high-fidelity electrophysiological signals alleviated motion artifacts. presented strategy generalizable could expand applicability more complex service conditions.
Язык: Английский
Процитировано
65
Nature Reviews Materials, Год журнала: 2024, Номер 9(4), С. 249 - 265
Опубликована: Фев. 29, 2024
Язык: Английский
Процитировано
53
Biosensors, Год журнала: 2023, Номер 13(11), С. 976 - 976
Опубликована: Ноя. 7, 2023
The promising field of organic electronics has ushered in a new era biosensing technology, thus offering frontier for applications both medical diagnostics and environmental monitoring. This review paper provides comprehensive overview electronics’ remarkable progress potential applications. It explores the multifaceted aspects materials devices, thereby highlighting their unique advantages, such as flexibility, biocompatibility, low-cost fabrication. delves into diverse range biosensors enabled by electronics, including electrochemical, optical, piezoelectric, thermal sensors, showcasing versatility detecting biomolecules, pathogens, pollutants. Furthermore, integrating wearable devices Internet Things (IoT) ecosystem is discussed, wherein they offer real-time, remote, personalized monitoring solutions. also addresses current challenges future prospects biosensing, emphasizing breakthroughs medicine, sustainability, advancement human health well-being.
Язык: Английский
Процитировано
46
Materials Today, Год журнала: 2024, Номер 72, С. 140 - 162
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
39
ACS Applied Electronic Materials, Год журнала: 2024, Номер 6(2), С. 1385 - 1395
Опубликована: Фев. 13, 2024
Flexible and wearable sensors have a crucial impact on the development of intelligent information technology. However, current commercial cannot meet relevant performance requirements. Herein, based electrospinning process, extra polarization, triboelectric nanogenerator technologies, we propose high-performance flexible sensor (HFWS) with self-powered breathable function, which is constructed by polarized polyvinylidene fluoride-barium titanate (PVDF-BTO) electrospun film Ni fabric electrode. After optimization β-phase content in PVDF BTO nanoparticles, an high-voltage polarization operation continually used to improve further enhance performance. Benefiting from excellent performance, HFWS exhibits several times higher signal-to-noise ratio (37.01 dB), sensitivity (2.62 ± 0.11 V/kPa), power density (4.62 W/m2) compared previous similar studies. In addition, for stable molecular phase structure PVDF-BTO film, has various good durability stability machinery, washing, environment, other aspects. Our finding potential value field devices, smart healthcare, life.
Язык: Английский
Процитировано
32
Cyborg and Bionic Systems, Год журнала: 2024, Номер 5
Опубликована: Янв. 1, 2024
With the prevalence of cardiovascular disease, it is imperative that medical monitoring and treatment become more instantaneous comfortable for patients. Recently, wearable implantable optoelectronic devices can be seamlessly integrated into human body to enable physiological in an imperceptible spatiotemporally unconstrained manner, opening countless possibilities intelligent healthcare paradigm. To achieve biointegrated cardiac healthcare, researchers have focused on novel strategies construction flexible/stretchable systems. Here, we overview progress flexible stretchable optoelectronics devices. Firstly, device design addressed, including mechanical design, interface adhesion, encapsulation strategies. Next, practical applications monitoring, optogenetics, nongenetic stimulation are presented. Finally, outlook systems discussed.
Язык: Английский
Процитировано
25
Science, Год журнала: 2024, Номер 386(6720), С. 431 - 439
Опубликована: Окт. 24, 2024
Hydrogels, known for their mechanical and chemical similarity to biological tissues, are widely used in biotechnologies, whereas semiconductors provide advanced electronic optoelectronic functionalities such as signal amplification, sensing, photomodulation. Combining semiconducting properties with hydrogel designs can enhance biointeractive functions intimacy at biointerfaces, but this is challenging owing the low hydrophilicity of polymer semiconductors. We developed a solvent affinity–induced assembly method that incorporates water-insoluble into double-network hydrogels. These exhibited tissue-level moduli soft 81 kilopascals, stretchability 150% strain, charge-carrier mobility up 1.4 square centimeters per volt second. When they interfaced modulus enables alleviated immune reactions. The hydrogel’s high porosity enhances molecular interactions semiconductor-biofluid interfaces, resulting photomodulation higher response volumetric biosensing sensitivity.
Язык: Английский
Процитировано
21