Integrating the milk microbiome signatures in mastitis: milk-omics and functional implications

World Journal of Microbiology and Biotechnology, Год журнала: 2025, Номер 41(2)

Опубликована: Янв. 18, 2025

Mammalian milk contains a variety of complex bioactive and nutritional components microorganisms. These microorganisms have diverse compositions functional roles that impact host health disease pathophysiology, especially mastitis. The advent use high throughput omics technologies, including metagenomics, metatranscriptomics, metaproteomics, metametabolomics, as well culturomics in microbiome studies suggest strong relationships between phenotype signatures While single undoubtedly contributed to our current understanding mastitis, they often provide limited information, targeting only biological viewpoint which is insufficient system-wide information necessary for elucidating the footprints molecular mechanisms driving mastitis dysbiosis. Therefore, integrating multi-omics approach research could generate new knowledge, improve structural ecosystem, insights sustainable control management.

Язык: Английский

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Draft genome sequencing of multidrug-resistant Pseudomonas asiatica strains isolated from dairy cows with clinical mastitis and their farm environment

Microbiology Resource Announcements, Год журнала: 2024, Номер 13(11)

Опубликована: Окт. 15, 2024

ABSTRACT We report, for the first time, draft genomes of four multidrug-resistant Pseudomonas asiatica strains isolated from milk (2M1), feces (2F1 and 2F2), farm soil (2S1) samples dairy cows with clinical mastitis. The assembled these were 5.7 Mbp, 62.8% G + C content, 50× genome coverage.

Язык: Английский

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Epidemiological and Therapeutic Profile of Mastitis in Small Ruminants in the Labé Region (Guinea)

Journal of Biosciences and Medicines, Год журнала: 2025, Номер 13(02), С. 500 - 509

Опубликована: Янв. 1, 2025

Язык: Английский

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Identification of Natural Compounds as Inhibitors of Clumping Factor A in staphylococcus aureus to Combat Bovine Mastitis: An in-Silico Approach

Biocatalysis and Agricultural Biotechnology, Год журнала: 2025, Номер unknown, С. 103556 - 103556

Опубликована: Март 1, 2025

Язык: Английский

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In Vitro Adhesion and Invasion Rates of Staphylococcus aureus Isolated from Mastitic Cows Are Modulated by the agr System and MSCRAMM Genes

Veterinary Sciences, Год журнала: 2025, Номер 12(3), С. 270 - 270

Опубликована: Март 13, 2025

Mastitis, an inflammatory condition of the udder, can be caused by entry Staphylococcus aureus, whose adhesion to mammary epithelial cells is influenced virulence factors such as microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) and accessory gene regulator (agr) system. Our goal was determine invasion rates S. aureus isolates from clinical (mild moderate) subclinical mastitis assess impact MSCRAMM genes agr types on disease severity. Clinical predominantly carried agrII (p < 0.0083) multiple genes, correlating with high capacity but reduced regardless Remarkably, isolates, mainly agr-negative (85.7%), showed increased cellular 0.0001), possibly due expression agr-mediated factors. These findings contribute understanding pathogen–host dynamics in bovine highlight importance both MSCRAMMs system modulating insights inform targeted interventions for prevention treatment.

Язык: Английский

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Longitudinal surveillance and analysis of antimicrobial resistance in bovine pathogens in North Gujarat: an 18-month perspective

Deleted Journal, Год журнала: 2025, Номер 7(5)

Опубликована: Апрель 28, 2025

Язык: Английский

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Thermographic Assessment of Mastitis Progression in Sahiwal Cattle: Insights into the Patterns in the Natural Course of Infection

Microbial Pathogenesis, Год журнала: 2024, Номер unknown, С. 106964 - 106964

Опубликована: Сен. 1, 2024

Язык: Английский

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Whole Genome Sequencing (WGS) Analysis of Antimicrobial Resistance (AMR) Milk and Dairy-Derived Pathogens from Anand, Gujarat, India

Microbial Pathogenesis, Год журнала: 2024, Номер unknown, С. 107076 - 107076

Опубликована: Окт. 1, 2024

Язык: Английский

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Risk factors for dairy cows mastitis in Algeria, antibiotic resistance and molecular typing of the causative Staphylococcus aureus

Veterinary Research Communications, Год журнала: 2024, Номер 48(5), С. 3007 - 3018

Опубликована: Июль 4, 2024

Язык: Английский

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Isolation and Determination of Antibiotic Resistance Pattern of Bacterial Agents of Subclinical Mastitis in Cows of Masal City, Guilan

Опубликована: Авг. 1, 2024

Язык: Английский

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