Recent mitochondria-immobilized fluorescent probes for high-fidelity bioimaging: From design to application

Coordination Chemistry Reviews, Год журнала: 2025, Номер 529, С. 216456 - 216456

Опубликована: Янв. 21, 2025

Язык: Английский

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Construction of a NIR fluorescent probe for tracking mitochondrial HOCl during liver injury

Journal of Photochemistry and Photobiology B Biology, Год журнала: 2025, Номер 265, С. 113136 - 113136

Опубликована: Фев. 25, 2025

Язык: Английский

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A novel ultrafast and highly sensitive NIR fluorescent probe for the detection of organophosphorus pesticides in foods and biological systems

Food Chemistry, Год журнала: 2024, Номер 463, С. 141172 - 141172

Опубликована: Сен. 7, 2024

Язык: Английский

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A dual-functional fluorescent probe for biosystem imaging and food safety monitoring of HSO3- with high selectivity and sensitivity

Analytical and Bioanalytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 22, 2025

Язык: Английский

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IR783‐Stabilized Nanodrugs Enhance Anticancer Immune Response by Synergizing Oxidation Therapy and Epigenetic Modulation

Advanced Science, Год журнала: 2025, Номер unknown

Опубликована: Март 27, 2025

Abstract Immune evasion and metastasis are the leading causes of poor prognosis in triple‐negative breast cancer treatment. Since current standard immunotherapies have limited efficacy due to immunologically cold microenvironment, it is crucial explore new strategies sensitize anticancer immune response. In this study, found that incorporating β ‐lapachone‐based oxidation therapy with CUDC101‐initiated epigenetic regulation results synergistic antitumor effects potent activation. To co‐deliver these two hydrophobic drugs, IR783 cyanine structure serves as stabilizer form a nanoformulation based on small molecule self‐assembly. Such IR783‐stabilized nanodrugs can not only lead cell apoptosis through HDAC inhibition‐enhanced but also cooperatively induce immunogenic death promote pro‐inflammatory cytokine gene expression reshape immunosuppressive microenvironment. Besides, inhibit both primary distant tumor growth effectively by elevating systemic immunity. This study provides promising approach synergize modulation for safe efficient immunotherapy.

Язык: Английский

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A long wavelength fluorescent probe for detecting viscosity and its application in liquid foods and bioimaging

Food Chemistry, Год журнала: 2025, Номер unknown, С. 144194 - 144194

Опубликована: Апрель 1, 2025

Язык: Английский

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