Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 144194 - 144194
Published: April 1, 2025
Language: Английский
Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 144194 - 144194
Published: April 1, 2025
Language: Английский
Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 529, P. 216456 - 216456
Published: Jan. 21, 2025
Language: Английский
Citations
4Journal of Photochemistry and Photobiology B Biology, Journal Year: 2025, Volume and Issue: 265, P. 113136 - 113136
Published: Feb. 25, 2025
Language: Английский
Citations
1Food Chemistry, Journal Year: 2024, Volume and Issue: 463, P. 141172 - 141172
Published: Sept. 7, 2024
Language: Английский
Citations
4Analytical and Bioanalytical Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: March 22, 2025
Language: Английский
Citations
0Advanced Science, Journal Year: 2025, Volume and Issue: unknown
Published: March 27, 2025
Abstract Immune evasion and metastasis are the leading causes of poor prognosis in triple‐negative breast cancer treatment. Since current standard immunotherapies have limited efficacy due to immunologically cold microenvironment, it is crucial explore new strategies sensitize anticancer immune response. In this study, found that incorporating β ‐lapachone‐based oxidation therapy with CUDC101‐initiated epigenetic regulation results synergistic antitumor effects potent activation. To co‐deliver these two hydrophobic drugs, IR783 cyanine structure serves as stabilizer form a nanoformulation based on small molecule self‐assembly. Such IR783‐stabilized nanodrugs can not only lead cell apoptosis through HDAC inhibition‐enhanced but also cooperatively induce immunogenic death promote pro‐inflammatory cytokine gene expression reshape immunosuppressive microenvironment. Besides, inhibit both primary distant tumor growth effectively by elevating systemic immunity. This study provides promising approach synergize modulation for safe efficient immunotherapy.
Language: Английский
Citations
0Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 144194 - 144194
Published: April 1, 2025
Language: Английский
Citations
0