Optimized green synthesis of silver nanoparticles from guarana seed skin extract with antibacterial potential
Green Processing and Synthesis,
Год журнала:
2025,
Номер
14(1)
Опубликована: Янв. 1, 2025
Abstract
This
study
optimizes
the
green
synthesis
of
silver
nanoparticles
(AgNPs)
using
seed
skin
extract
guarana
(
Paullinia
cupana
)
as
a
natural
stabilizing
and
reducing
agent.
Employing
Taguchi
design,
nine
experiments
were
conducted
across
three
levels
for
four
key
factors:
reaction
temperature,
pH,
nitrate
concentration,
concentration
to
minimize
AgNP
size.
Optimal
conditions
–
pH
11,
5
mM
nitrate,
50°C
1%
(m/v)
produced
quasi-spherical
AgNPs
with
an
average
size
∼26
nm.
Chemical
analysis
revealed
caffeine
main
organic
compound
potassium
oxide
primary
inorganic
component.
UV-vis
spectra
showed
absorption
peak
at
438
nm,
X-ray
diffraction
confirmed
typical
peaks.
Further
identified
polyphenols,
alkaloids,
flavonoids
agents.
A
high
(180.0
±
0.2
ppm)
was
through
ICP-OES,
demonstrated
significant
antibacterial
activity
against
Escherichia
coli
Staphylococcus
aureus
,
minimum
inhibitory
50
μg·mL
−1
.
underscores
sustainability
promising
alternative
traditional
nanoparticle
production
methods.
Язык: Английский
Silver Nanoparticles (AgNPs): Comprehensive Insights into Bio/Synthesis, Key Influencing Factors, Multifaceted Applications, and Toxicity─A 2024 Update
ACS Omega,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 18, 2025
Silver
nanoparticles
(AgNPs)
are
widely
recognized
for
their
unique
optical,
electronic,
and
antibacterial
properties,
enabling
use
in
biosensing,
photonics,
electronics,
drug
delivery,
antimicrobial
treatments.
Green
chemistry-based
biological
synthesis
methods
offer
an
eco-friendly
alternative
to
traditional
chemical
techniques.
Among
metallic
(NPs)
metal
oxides,
those
derived
from
plant
extracts
exhibit
notable
medicinal
properties.
Due
exceptional
stability
low
reactivity,
AgNPs
particularly
well-suited
various
applications.
can
be
synthesized
through
chemical,
physical,
or
methods,
each
with
distinct
benefits
challenges.
Chemical
physical
approaches
often
involve
complex
purification,
reactive
reagents,
high
energy
demands,
while
though
slower,
provide
sustainable
solutions.
The
chosen
method
strongly
influences
the
stability,
size,
purity
of
resulting
NPs.
This
review
emphasizes
importance
selecting
appropriate
optimize
characteristics
functionality
silver
It
consolidates
research
spanning
past
two
decades,
including
most
recent
findings
2024.
A
comprehensive
electronic
search
databases
such
as
PubMed,
Scopus,
ScienceDirect,
Cochrane,
Google
Scholar
was
conducted
up-to-date
overview
advances
applications
nanoparticles.
Язык: Английский
Unlocking the Power of Nanohybrids: A Critical Review on Carbon Nanomaterial-Functionalized Silver Nanoparticles for Advanced Antimicrobial Applications
Colloids and Surfaces B Biointerfaces,
Год журнала:
2025,
Номер
unknown, С. 114678 - 114678
Опубликована: Апрель 1, 2025
Язык: Английский
Ultrafast green synthesis of silver nanoparticles as fluorescent nanosensors for determination of isoniazid and nitrofurantoin in biological fluids and pharmaceuticals
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Май 3, 2025
Abstract
The
current
study
presents
a
green,
straightforward,
and
ultrafast
microwave-assisted
method
for
the
synthesis
of
Ag-NPs
in
only
40
s,
using
Paeonia
officinalis
root
extract
as
reducing
agent,
first
time.
Characterization
produced
was
carried
out
different
spectroscopic
microscopic
methods.
They
exhibited
strong
emission
peak
at
318
nm
following
excitation
227
nm.
developed
were
utilized
green
fluorescent
nanosensor
determination
isoniazid
(ISN)
nitrofurantoin
sodium
(NIF).
native
fluorescence
observed
to
be
quantitatively
quenched
by
studied
drugs.
Validation
linear
relationship
ISN
NIF
range
20.0-100.0
µM
10.0–60.0
with
detection
limits
1.12
0.98
µM,
respectively.
Due
high
selectivity
sensitivity,
suggested
also
applied
estimation
biological
fluid
samples
pharmaceutical
formulations
acceptable
%
RSD
recoveries.
Assessment
Ag-NPs’
antimicrobial
activity
performed,
synthesized
showed
noteworthy
activities.
evaluation
method’s
eco-friendliness
greenness
performed
AGREE
ComplexGAPI
metrics.
ICHQ2
(R2)
guidelines
followed
validate
method.
Язык: Английский
Eco-friendly four spectrophotometric approaches for the simultaneous determination of the recently FDA-approved combination, bupivacaine and meloxicam in pharmaceutical dosage forms
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Ноя. 11, 2024
In
this
study,
bupivacaine
(BUP)
and
meloxicam
(MLX)
were
simultaneously
assayed
in
their
co-formulated
ampoules
without
interference
using
four
affordable,
sensitive,
eco-friendly
spectrophotometric
methods.
The
assay
of
MLX
at
359.3
nm
over
the
concentration
range
1.0-15.0
µg/mL
was
accomplished
a
direct
UV-spectrophotometric
method
(Method
I)
from
BUP.
However,
there
significant
overlap
between
spectra
BUP
MLX,
making
it
difficult
to
determine
directly
UV
spectrum.
Therefore,
various
UV-based
techniques,
including
second
derivative
spectrophotometry
II),
ratio
subtraction
III),
absorption
factor
IV),
used
5.0-80.0
µg/mL.
proposed
methods
could
studied
drugs
with
challenging
33.3:1.0
(BUP:
MLX),
which
increases
importance
current
study.
applied
estimate
commercial
high
%
recoveries
low
%RSD
values.
excellent
eco-friendliness
developed
demonstrated
GAPI
AGREE
metrics.
validated
according
ICHQ2(R2)
guidelines.
can
be
better
suited
for
routine
analysis
fixed-dose
combination
selectivity.
Язык: Английский