Drug Delivery System Based on CTAB/CS‐Modified Kanemite for Methotrexate and Its Cytotoxicity Against HepG2 Cells DOI Open Access

Yijun Liu,

Fang Guo,

Xiaoqiang Shang

и другие.

ChemistrySelect, Год журнала: 2024, Номер 9(38)

Опубликована: Окт. 1, 2024

Abstract Cationic cetyltrimethylammonium (CTAB) is an effective and common intercalator for interlayered modification in layered materials, while its biotoxicity remains issue. To improve biosafety biocompatibility of the drug delivery system, nontoxic chitosan (CS) was introduced into CTAB‐modified kanemite (Ka‐CTAB). Accordingly, obtained Ka‐CTAB/CS further used as a carrier methotrexate (MTX). Various characterizations were employed to investigate system based on Ka‐CTAB/CS. Results revealed that loading capacity MTX about 13.47%, exhibited slow sustained release drugs either phosphate buffer solution (pH = 7.4) or HCl 1.35). The introduction CS not only replaced part CTAB composition but also prevented molecules falling off during drug‐releasing process. In methyl orange dye assay, concentration free shed from low 8.09 × 10 −7 mol/L after 24 h. vitro cell viability assay using HepG2 cells, lower cytotoxicity compared previous Ka‐CTAB.

Язык: Английский

Self-Assembled rGO-Integrated Cd-MOF as a High-Stability Electrode for Advanced Symmetric and Asymmetric Supercapacitors DOI
Usama Zahid, Fasiha Kashif

Energy & Fuels, Год журнала: 2025, Номер unknown

Опубликована: Янв. 29, 2025

Язык: Английский

Процитировано

2

Deep eutectic solvent-functionalized metal-organic frameworks in sorptive extraction techniques and their applications – A review DOI
Wajid Ali Khan, Muhammad Balal Arain,

Sana Balal

и другие.

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113201 - 113201

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

CRISPR/Cas12a trans-cleavage cascading dual-template exponential amplification reaction for electrochemiluminescent detection of 17β-estradiol in milk DOI
Hang Du, Yuyi Zhou,

Jiawen Wu

и другие.

Talanta, Год журнала: 2025, Номер 291, С. 127873 - 127873

Опубликована: Март 2, 2025

Язык: Английский

Процитировано

0

Structural Diversity and Fluorescent Sensing for Antibiotics and Nitrobenzene of Cd‐Based Sensors With Three Tricarboxylate Isomers DOI
Xue Yang, Wanting Liu,

Xiufang Hou

и другие.

Applied Organometallic Chemistry, Год журнала: 2025, Номер 39(5)

Опубликована: Апрель 8, 2025

ABSTRACT Three novel Cd (II) coordination polymers (Cd‐CPs) ( 1–3) , with the formula of [Cd(2‐DBB)(1,4‐bibz)(OH)]·H 2 O( 1 ), [Cd 3 (3‐DBB)(1,4‐bibz) ]·2H and [Cd(4‐HDBB)(1,4‐bibz) 0.5 ]( ) based on three soft organic isomers: n ‐(3,5‐dicarboxylato benzyloxy) benzoic acid = 2, 3, or 4‐H DBB), one linear N‐donor ligand 1,4‐bis(1‐imidazoly) benzene (1,4‐bibz) have been synthesized hydrothermally characterized by X‐ray single crystal diffraction, elemental analyses, thermogravimetric, UV, IR, PXRD technologies. The significant structural differences are both featuring 2D networks, but 3D framework due to change H DBB isomers. Despite differences, series Cd‐CPs exhibits similar fluorescence sensing properties for nitrobenzene (NB) low detection limits 1.05 μM 44.3 nM 59.1 respectively. However, these discovered detect different antibiotics, respectively: had a quenching effect ornidazole (ONZ) chloramphenicol (CHI). results theoretical calculation verified mechanism Cd‐CPs. Therefore, might be potential luminescent materials antibiotics NB in future.

Язык: Английский

Процитировано

0

Development of Citral-loaded active packaging for fresh-cut preservation using Water-resistant γ-Cyclodextrin Metal-organic Frameworks modified with cellulose acetate butyrate DOI

Zhicheng Wei,

Junxiang Zhu,

Xiaohan Chai

и другие.

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 162482 - 162482

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Innovative horizons of MOF-based electrode materials for next-generation energy storage and conversion: Bridging progress and challenges DOI
Usama Zahid, Fasiha Kashif

Materials Today Chemistry, Год журнала: 2025, Номер 45, С. 102705 - 102705

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Drug Delivery System Based on CTAB/CS‐Modified Kanemite for Methotrexate and Its Cytotoxicity Against HepG2 Cells DOI Open Access

Yijun Liu,

Fang Guo,

Xiaoqiang Shang

и другие.

ChemistrySelect, Год журнала: 2024, Номер 9(38)

Опубликована: Окт. 1, 2024

Abstract Cationic cetyltrimethylammonium (CTAB) is an effective and common intercalator for interlayered modification in layered materials, while its biotoxicity remains issue. To improve biosafety biocompatibility of the drug delivery system, nontoxic chitosan (CS) was introduced into CTAB‐modified kanemite (Ka‐CTAB). Accordingly, obtained Ka‐CTAB/CS further used as a carrier methotrexate (MTX). Various characterizations were employed to investigate system based on Ka‐CTAB/CS. Results revealed that loading capacity MTX about 13.47%, exhibited slow sustained release drugs either phosphate buffer solution (pH = 7.4) or HCl 1.35). The introduction CS not only replaced part CTAB composition but also prevented molecules falling off during drug‐releasing process. In methyl orange dye assay, concentration free shed from low 8.09 × 10 −7 mol/L after 24 h. vitro cell viability assay using HepG2 cells, lower cytotoxicity compared previous Ka‐CTAB.

Язык: Английский

Процитировано

1