Drug Delivery System Based on CTAB/CS‐Modified Kanemite for Methotrexate and Its Cytotoxicity Against HepG2 Cells DOI Open Access

Yijun Liu,

Fang Guo,

Xiaoqiang Shang

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(38)

Published: Oct. 1, 2024

Abstract Cationic cetyltrimethylammonium (CTAB) is an effective and common intercalator for interlayered modification in layered materials, while its biotoxicity remains issue. To improve biosafety biocompatibility of the drug delivery system, nontoxic chitosan (CS) was introduced into CTAB‐modified kanemite (Ka‐CTAB). Accordingly, obtained Ka‐CTAB/CS further used as a carrier methotrexate (MTX). Various characterizations were employed to investigate system based on Ka‐CTAB/CS. Results revealed that loading capacity MTX about 13.47%, exhibited slow sustained release drugs either phosphate buffer solution (pH = 7.4) or HCl 1.35). The introduction CS not only replaced part CTAB composition but also prevented molecules falling off during drug‐releasing process. In methyl orange dye assay, concentration free shed from low 8.09 × 10 −7 mol/L after 24 h. vitro cell viability assay using HepG2 cells, lower cytotoxicity compared previous Ka‐CTAB.

Language: Английский

Self-Assembled rGO-Integrated Cd-MOF as a High-Stability Electrode for Advanced Symmetric and Asymmetric Supercapacitors DOI
Usama Zahid, Fasiha Kashif

Energy & Fuels, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

Language: Английский

Citations

2
Deep eutectic solvent-functionalized metal-organic frameworks in sorptive extraction techniques and their applications – A review DOI
Wajid Ali Khan, Muhammad Balal Arain,

Sana Balal

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113201 - 113201

Published: Feb. 1, 2025

Language: Английский

Citations

0
CRISPR/Cas12a trans-cleavage cascading dual-template exponential amplification reaction for electrochemiluminescent detection of 17β-estradiol in milk DOI
Hang Du, Yuyi Zhou,

Jiawen Wu

et al.

Talanta, Journal Year: 2025, Volume and Issue: 291, P. 127873 - 127873

Published: March 2, 2025

Language: Английский

Citations

0
Structural Diversity and Fluorescent Sensing for Antibiotics and Nitrobenzene of Cd‐Based Sensors With Three Tricarboxylate Isomers DOI
Xue Yang, Wanting Liu,

Xiufang Hou

et al.

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(5)

Published: April 8, 2025

ABSTRACT Three novel Cd (II) coordination polymers (Cd‐CPs) ( 1–3) , with the formula of [Cd(2‐DBB)(1,4‐bibz)(OH)]·H 2 O( 1 ), [Cd 3 (3‐DBB)(1,4‐bibz) ]·2H and [Cd(4‐HDBB)(1,4‐bibz) 0.5 ]( ) based on three soft organic isomers: n ‐(3,5‐dicarboxylato benzyloxy) benzoic acid = 2, 3, or 4‐H DBB), one linear N‐donor ligand 1,4‐bis(1‐imidazoly) benzene (1,4‐bibz) have been synthesized hydrothermally characterized by X‐ray single crystal diffraction, elemental analyses, thermogravimetric, UV, IR, PXRD technologies. The significant structural differences are both featuring 2D networks, but 3D framework due to change H DBB isomers. Despite differences, series Cd‐CPs exhibits similar fluorescence sensing properties for nitrobenzene (NB) low detection limits 1.05 μM 44.3 nM 59.1 respectively. However, these discovered detect different antibiotics, respectively: had a quenching effect ornidazole (ONZ) chloramphenicol (CHI). results theoretical calculation verified mechanism Cd‐CPs. Therefore, might be potential luminescent materials antibiotics NB in future.

Language: Английский

Citations

0
Development of Citral-loaded active packaging for fresh-cut preservation using Water-resistant γ-Cyclodextrin Metal-organic Frameworks modified with cellulose acetate butyrate DOI

Zhicheng Wei,

Junxiang Zhu,

Xiaohan Chai

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 162482 - 162482

Published: April 1, 2025

Language: Английский

Citations

0
Innovative horizons of MOF-based electrode materials for next-generation energy storage and conversion: Bridging progress and challenges DOI
Usama Zahid, Fasiha Kashif

Materials Today Chemistry, Journal Year: 2025, Volume and Issue: 45, P. 102705 - 102705

Published: April 1, 2025

Language: Английский

Citations

0
Drug Delivery System Based on CTAB/CS‐Modified Kanemite for Methotrexate and Its Cytotoxicity Against HepG2 Cells DOI Open Access

Yijun Liu,

Fang Guo,

Xiaoqiang Shang

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(38)

Published: Oct. 1, 2024

Abstract Cationic cetyltrimethylammonium (CTAB) is an effective and common intercalator for interlayered modification in layered materials, while its biotoxicity remains issue. To improve biosafety biocompatibility of the drug delivery system, nontoxic chitosan (CS) was introduced into CTAB‐modified kanemite (Ka‐CTAB). Accordingly, obtained Ka‐CTAB/CS further used as a carrier methotrexate (MTX). Various characterizations were employed to investigate system based on Ka‐CTAB/CS. Results revealed that loading capacity MTX about 13.47%, exhibited slow sustained release drugs either phosphate buffer solution (pH = 7.4) or HCl 1.35). The introduction CS not only replaced part CTAB composition but also prevented molecules falling off during drug‐releasing process. In methyl orange dye assay, concentration free shed from low 8.09 × 10 −7 mol/L after 24 h. vitro cell viability assay using HepG2 cells, lower cytotoxicity compared previous Ka‐CTAB.

Language: Английский

Citations

1