Journal of Nanomaterials,
Год журнала:
2024,
Номер
2024, С. 1 - 23
Опубликована: Янв. 8, 2024
Chronic
wounds,
which
include
venous
leg
ulcers,
diabetic
foot
and
pressure
are
a
global
health
issue
that
affects
between
1%
2%
of
the
developed
world’s
population.
wound
healing
necessitates
extensive
medical
intervention
at
costly
healthcare
expenses.
Wound
care
management
is
mainly
dependent
on
discovery
new
appropriate
chronic
dressing
materials,
it
remains
focus
research
in
care.
Biocompatible
metallic
nanoparticle-loaded
offers
novel
opportunity
for
effectively
overcoming
inherent
drawbacks
traditional
particularly
nonhealing
wounds
due
to
their
clinical
complexity,
example,
infections,
irritation,
trauma,
persistence
foreign
body
or
bacterial
proteins,
ischemia.
In
this
review,
we
will
primarily
advancements
nanoparticle-based
antibacterial
antioxidant
materials
(e.g.,
hydrogels,
electrospun
scaffolds,
sponges,
films)
treatment
overcome
limitations
dressings.
Journal of Drug Delivery Science and Technology,
Год журнала:
2024,
Номер
96, С. 105689 - 105689
Опубликована: Апрель 21, 2024
In
the
last
few
years,
wound
healing
and
development
of
"ideal"
biomaterials
that
provide
quick
recovery
minimize
scarring
have
represented
one
most
important
priorities
researchers.
this
direction,
silk
fibroin
(SF)
scaffolds
gained
substantial
awareness,
as
a
promising
polymer
owing
to
their
increased
biocompatibility,
outstanding
mechanical
properties,
biodegradability,
especially
tensile
strength.
Furthermore,
SF
is
acknowledged
accelerate
process
by
encouraging
cell
growth
proliferation,
also
migration
different
types
cells
are
included
in
stages
process.
Therefore,
metal
oxide
nanoparticles
(NPs),
such
iron
(FeO),
copper
(CuO),
zinc
(ZnO),
or
magnesium
(MgO)
NPs,
been
extensively
researched
for
antimicrobial
properties
ability
enhance
tissue
regeneration
addition
SF.
When
introduced
within
scaffolds,
these
NPs
impart
enhanced
including
improved
scaffold
stability
durability.
Moreover,
presence
could
increase
biocompatibility
facilitating
adhesion,
migration,
ultimately
promoting
processes.
The
incorporation
other
natural
polymers
into
has
thus
emerged
favorable
method
therapeutic
potential
developed
biomaterial.
This
review
aims
an
overview
advancements
containing
applications.
Journal of Nanomaterials,
Год журнала:
2024,
Номер
2024, С. 1 - 23
Опубликована: Янв. 8, 2024
Chronic
wounds,
which
include
venous
leg
ulcers,
diabetic
foot
and
pressure
are
a
global
health
issue
that
affects
between
1%
2%
of
the
developed
world’s
population.
wound
healing
necessitates
extensive
medical
intervention
at
costly
healthcare
expenses.
Wound
care
management
is
mainly
dependent
on
discovery
new
appropriate
chronic
dressing
materials,
it
remains
focus
research
in
care.
Biocompatible
metallic
nanoparticle-loaded
offers
novel
opportunity
for
effectively
overcoming
inherent
drawbacks
traditional
particularly
nonhealing
wounds
due
to
their
clinical
complexity,
example,
infections,
irritation,
trauma,
persistence
foreign
body
or
bacterial
proteins,
ischemia.
In
this
review,
we
will
primarily
advancements
nanoparticle-based
antibacterial
antioxidant
materials
(e.g.,
hydrogels,
electrospun
scaffolds,
sponges,
films)
treatment
overcome
limitations
dressings.
