Polymer-Based Functional Materials Loaded with Metal-Based Nanoparticles as Potential Scaffolds for the Management of Infected Wounds
Pharmaceutics,
Год журнала:
2024,
Номер
16(2), С. 155 - 155
Опубликована: Янв. 23, 2024
Wound
infection
due
to
bacterial
invasion
at
the
wound
site
is
one
of
primary
challenges
associated
with
delayed
healing.
Microorganisms
tend
form
biofilms
that
protect
them
from
harm,
leading
their
multidrug
resistance.
The
alarming
increase
in
antibiotic
resistance
poses
a
threat
Hence,
urgent
need
for
novel
dressing
materials
capable
managing
crucial
expediting
recovery.
There
considerable
interest
polymeric
dressings
embedded
bioactive
substances,
such
as
metal-based
nanoparticles,
potential
solutions
treating
microbially
infected
wounds.
Metal-based
nanoparticles
have
been
widely
used
management
wounds
broad
antimicrobial
efficacy.
This
review
focuses
on
polymer-based
and
loaded
like
silver,
gold,
magnesium
oxide,
or
zinc
oxide.
When
compared,
oxide-loaded
exhibited
higher
antibacterial
activity
against
Gram-positive
strains
silver
nanoparticle-loaded
gram-negative
strains.
However,
infused
both
displayed
synergistic
effect
bacteria.
Furthermore,
these
antibiofilm
generation
reactive
oxygen
species
while
accelerating
closure
vitro
vivo.
Язык: Английский
Advances in the study of polysaccharide-based hydrogel wound dressings
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
unknown, С. 142134 - 142134
Опубликована: Март 1, 2025
Язык: Английский
Cartilage-bioinspired tenacious concrete-like hydrogel verified via in-situ testing
Nature Communications,
Год журнала:
2025,
Номер
16(1)
Опубликована: Март 8, 2025
Polyvinyl
alcohol
(PVA)/polyethylene
glycol
(PEG)
hydrogels,
being
low-cost
and
abundant
materials,
can
demonstrate
tremendous
potential
in
applications
requiring
mechanical
robustness
by
harnessing
the
enhancements
afforded
a
structure
inspired
articular
cartilage
(AC).
This
study
presents
fabrication
of
bioinspired
PVA/PEG
(BPP)
hydrogel,
characterized
their
high
strength
low
friction
coefficient.
By
utilizing
concrete-like
composed
PVA
particles
fibers,
BPP
hydrogel
demonstrates
notable
properties
such
as
compressive
(86%,
29.5
MPa),
tensile
(265%,
10.5
fatigue
resistance,
impact
cut
resistance.
Moreover,
under
submerged
conditions,
it
exhibits
coefficient
(COF)
minimal
wear.
The
packaged
sensor
sensitivity,
linearity,
fast
response
time.
Ultimately,
we
endeavor
to
apply
straightforward
yet
competent
strategy
intelligent
protective
sensing
equipment,
showcasing
extensive
prospects
for
practical
applications.
Hydrogels
have
number
applications,
but
many,
is
required.
Here,
authors
report
preparation
with
cartilage-inspired
structure,
friction,
amongst
other
properties.
Язык: Английский
Highly Absorbent Polymers-Inspired Biomass Adhesive with Enhanced Strength and Water Retention Properties
ACS Sustainable Chemistry & Engineering,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 16, 2025
Язык: Английский
Emerging Technological Advancement for Chronic Wound Treatment and Their Role in Accelerating Wound Healing
ACS Applied Bio Materials,
Год журнала:
2024,
Номер
7(11), С. 7101 - 7132
Опубликована: Окт. 28, 2024
Chronic
wounds
are
a
major
healthcare
burden
and
may
severely
affect
the
social,
mental,
economic
status
of
patients.
Any
impairment
in
wound
healing
stages
due
to
underlying
factors
leads
prolonged
time
subsequently
chronic
wounds.
Traditional
approaches
for
treatment
include
dressing
free
local
therapy,
tissue
engineering
based
scaffold
therapies.
However,
traditional
therapies
need
improvisation
have
been
advanced
through
breakthrough
technologies.
The
present
review
spans
further
gives
an
extensive
account
advancements
Cutting
edge
technologies,
such
as
3D
printing,
which
includes
inkjet
fused
deposition
modeling,
digital
light
processing,
extrusion-based
microneedle
array-based
therapies,
gene
microRNAs
(miRNAs)
smart
dressings
real
monitoring
conditions
assessment
pH,
temperature,
oxygen,
moisture,
metabolites,
their
use
planning
better
strategies
discussed
detail.
future
direction
treatments
that
will
aid
lowering
caused
Язык: Английский
The effect of MgO nanoparticle on PVA/PEG-based membranes for potential application in wound healing
Journal of Biomaterials Science Polymer Edition,
Год журнала:
2024,
Номер
35(13), С. 1963 - 1977
Опубликована: Июль 1, 2024
The
interest
in
wound
dressings
increased
ten
years
ago.
Wound
care
practitioners
can
now
use
interactive/bioactive
and
tissue-engineered
skin
substitutes.
Several
bandages
heal
burns,
but
none
treat
all
chronic
wounds.
This
study
formulates
a
composite
material
from
70%
polyvinyl
alcohol
(PVA)
30%
polyethylene
glycol
(PEG)
with
0.2,
0.4,
0.6
wt%
magnesium
oxide
nanoparticles.
aims
to
create
biodegradable
dressing.
A
Fourier
Transform
Infrared
(FTIR)
shows
that
PVA,
PEG,
MgO
hydrogen
bonding
interactions.
Hydrophilic
characteristics
are
shown
by
the
polymeric
blend's
56.289°
contact
angle.
also
lowers
angle,
making
film
more
hydrophilic.
Hydrophilicity
improves
biocompatibility,
live
cell
adhesion,
healing,
dressing
degradability.
Differential
Scanning
Calorimeter
(DSC)
findings
suggest
PVA/PEG
combination
melted
at
53.16
°C.
However,
adding
different
weight
fractions
of
nanoparticles
nanocomposite's
melting
temperature
(T
Язык: Английский