Material Design, Fabrication Strategies, and the Development of Multifunctional Hydrogel Composites Dressings for Skin Wound Management

Biomacromolecules, Год журнала: 2025, Номер unknown

Опубликована: Фев. 17, 2025

The skin is fragile, making it very vulnerable to damage and injury. Untreated wounds can pose a serious threat human health. Three-dimensional polymer network hydrogels have broad application prospects in wound dressings due their unique properties structure. therapeutic effect of traditional limited, while multifunctional composite show greater potential. Multifunctional regulate moisture through formula adjustment. Moreover, be combined with bioactive ingredients improve performance healing applications. Stimulus-responsive respond specifically the environment meet needs different stages. This review summarizes material types, structure, properties, design considerations, formulation strategies for hydrogel used healing. We discuss various types recently developed dressings, highlights importance tailoring physicochemical addresses potential challenges preparing dressings.

Язык: Английский

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Polyaminoglycoside nanosystem expressing antimicrobial peptides for multistage chronic wound management

Journal of Controlled Release, Год журнала: 2025, Номер unknown, С. 113657 - 113657

Опубликована: Март 1, 2025

Язык: Английский

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Multifunctional alginate-sinapic acid/arginine-strontium hydrogel for promoting diabetic wound healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142460 - 142460

Опубликована: Март 1, 2025

Язык: Английский

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Exudate management nonwovens loaded with Cirsium japonicum DC extract for enhanced hemostatic and wound healing

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114673 - 114673

Опубликована: Апрель 1, 2025

Язык: Английский

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Injectable glycyrrhizic acid-based hydrogel with Immunoregulatory and angiogenic properties for diabetic wound healing

Materials & Design, Год журнала: 2025, Номер unknown, С. 113928 - 113928

Опубликована: Апрель 1, 2025

Язык: Английский

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New Direction in Antimicrobial Delivery System: Preparation and Applications of Hydrogel Microspheres

Pharmaceutics, Год журнала: 2025, Номер 17(4), С. 529 - 529

Опубликована: Апрель 17, 2025

Antimicrobial delivery systems have undergone extensive development, yet conventional carriers still exhibit limitations such as low loading capacity, inadequate controlled release mechanisms, and cytotoxicity. Recent studies increasingly demonstrated the potential of Hydrogel Microspheres (HMSs) for antimicrobial delivery. These microspheres small dimensions, high drug-loading ability to achieve deep-targeted delivery, complemented by adjustable physicochemical properties biocompatibility that create favorable conditions transportation. This review systematically examines HMS preparation strategies, characteristic properties, transported antimicrobials, therapeutic applications. Particular emphasis is placed on critical parameters governing performance, especially those influencing drug dynamics. We conclude addressing current challenges proposing actionable strategies material optimization clinical translation. work aims advance HMS-based more effective infection control.

Язык: Английский

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An Overview on Recent Progress of Microsphere‐Hydrogel Combination Systems as Scaffolds for Tissue Engineering

ChemistrySelect, Год журнала: 2025, Номер 10(16)

Опубликована: Апрель 1, 2025

Abstract Tissue engineering aiming to develop and manufacture bioactive tissue or organ substitutes has been extensively studied. As an ideal scaffold material, the microsphere‐hydrogel combination system (MHCS), which combines excellent functionalities of hydrogels unique structural advantages microspheres, widely used in development biological for engineering. With adjustable mechanical properties, MHCS can simulate extracellular matrix‐like microstructure microenvironment conducive cell growth. These properties endow with repair, leading significant progress regeneration bone, skin, blood vessels, nerves, other tissues. In this paper, we reviewed latest construction based on natural polymers, synthetic inorganic materials, their composites. We also classified raw materials that were utilized microspheres discussed applications MHCS. Finally, challenges perspectives emphasized pointed out direction future development, such as conducted advanced processing technologies multidisciplinary cooperation solve limitations uneven microsphere distribution mismatched degradation rates, thus providing a reference design fabrication field

Язык: Английский

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3D Electrospun nanofiber sponges of insect chitosan/pullulan/citric acid embedded with ZnMOF in situ for enhanced healing of MRSA-infected wounds

Chemical Engineering Journal, Год журнала: 2024, Номер 498, С. 155388 - 155388

Опубликована: Сен. 1, 2024

Язык: Английский

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Preparation and characterization of pH-responsive Janus composite membranes with unidirectional moisture drainage and antioxidant resistance

Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2024, Номер 701, С. 134916 - 134916

Опубликована: Июль 24, 2024

Язык: Английский

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A pro-healing short-chain antimicrobial peptide that inhibits sepsis

Science China Materials, Год журнала: 2024, Номер unknown

Опубликована: Авг. 28, 2024

Язык: Английский

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