Current Opinion in Supportive and Palliative Care,
Год журнала:
2024,
Номер
18(4), С. 183 - 190
Опубликована: Окт. 30, 2024
Purpose
of
the
review
Breathlessness
may
evoke
existential
threat
but
also
affect
person
with
serious
illness
or
their
caregiver/s
in
other
important
ways
which
can
be
considered
‘existential’.
This
explores
aspects
breathlessness
people
and
presents
recent
studies
assessment
management
associated
distress
suffering.
Recent
findings
Both
are
multidimensional
include
a
range
constructs,
many
have
behavioural
consequences.
Existential
tracks
closely
distressing
breathing
potentially
due
to
shared
underlying
neurobiological
processing.
Paradoxically
‘contagious’
isolating
effects
related
been
recently
highlighted.
Approaches
screening
vary.
Preliminary
investigated
novel
approaches
breathing-related
anxiety
distress.
Summary
Studies
constructs
as
outcome
measures
scarce.
Interventions
for
developed
those
malignant
disease
beneficial
non-malignant
conditions,
adaptations
required.
Recently
proposed
taxonomies
distress/concerns
guide
direct
therapeutic
interventions
living
breathlessness-related
Neglecting
represents
missed
opportunity
support
holistic
well-being
illness.
Cognitive Affective & Behavioral Neuroscience,
Год журнала:
2024,
Номер
24(2), С. 228 - 245
Опубликована: Фев. 14, 2024
Abstract
Anxiety
disorders
affect
millions
of
people
worldwide
and
present
a
challenge
in
neuroscience
research
because
their
substantial
heterogeneity
clinical
presentation.
While
great
deal
progress
has
been
made
understanding
the
neurobiology
fear
anxiety,
these
insights
have
not
led
to
effective
treatments.
Understanding
relationship
between
phenotypic
underlying
biology
is
critical
first
step
solving
this
problem.
We
show
translation,
reverse
computational
modeling
can
contribute
refined,
cross-species
anxiety
as
well
disorders.
More
specifically,
we
outline
how
animal
models
be
leveraged
develop
testable
hypotheses
humans
by
using
targeted,
approaches
ethologically
informed
behavioral
paradigms.
discuss
translational
that
guide
prioritize
nontraditional
species.
Finally,
advocate
for
use
harmonize
cross-methodology
into
anxiety.
Together,
approach
will
help
bridge
widening
gap
currently
conceptualize
diagnose
disorders,
aid
discovery
better
treatments
conditions.
Abstract
Background
Monkeypox
has
emerged
as
a
global
health
concern,
necessitating
preventive
measures
and
awareness
among
healthcare
students.
Understanding
nursing
students’
fears,
concerns,
practices
regarding
can
help
improve
preparedness
response
strategies.
Aim
This
study
aimed
to
assess
the
levels
of
fear,
related
monkeypox
students
at
Beni
Suef
University,
Egypt,
during
2024–2025
academic
year.
Methods
A
cross-sectional
descriptive
design
was
employed,
involving
505
systematically
randomized
recruited.
Data
collection
utilized
three
validated
tools:
Fear
Scale,
Concern
Preventive
Practices
Scale.
Reliability
confirmed
with
Cronbach’s
alpha
values
ranging
from
0.87
0.94.
analysis
included
statistics,
Spearman
correlation,
multiple
linear
regression
using
SPSS
Version
23.
Results
Most
(56.2%)
rarely
worried
about
infection,
though
49.2%
reported
anxiety
influenced
by
media
coverage.
High
were
noted,
60.6%
frequently
practicing
hygiene
measures.
strong
positive
correlation
between
concern
fear
(
r
=
0.646,
p
<
0.001)
moderate
0.229,
0.001).
also
significantly
correlated
0.432,
Multiple
(R²
0.216,
F
22.633,
revealed
that
predictor
practices,
while
had
but
non-significant
effect
(B
0.138,
0.156).
Age
not
significant
0.251,
0.637),
whereas
family
income
showed
negative
association
-1.885,
0.010).
Conclusion
The
concerns
students,
generally
high
adherence
practices.
Implication
Findings
suggest
need
for
targeted
education
programs
address
monkeypox-related
enhance
measures,
thus
improving
readiness
respond
emerging
threats.
Psychiatry International,
Год журнала:
2024,
Номер
5(1), С. 53 - 73
Опубликована: Фев. 4, 2024
The
primary
focus
of
this
review
is
to
rigorously
explore
the
application
and
significance
coping
strategies
within
domains
clinical
psychology
neuropsychology.
These
consist
a
variety
techniques,
behaviors,
cognitive
interventions,
their
critical
role
in
reinforcing
resilience
facilitating
adaptive
responses
stressors
has
been
highlighted.
This
study
explores
complex
neuropsychological
links
between
brain’s
stress
pathways
use
mechanisms.
neural
aspects
stress,
how
they
can
be
influenced
by
strategies,
are
detailed,
illustrating
profound
impact
that
these
mechanisms
have
at
neurobiological
level.
Delving
into
underpinnings,
will
shed
light
on
response
brain
interact
with,
modulated
by,
various
strategies.
particularly
salient
when
addressing
multifaceted
challenges
faced
individuals
with
or
mental
health
issues.
While
span
broad
spectrum,
from
introspection
reframing
behavioral
activation
social
support
seeking,
integration
remain
diverse
contexts.
endeavors
elucidate
theoretical
underpinnings
empirical
support,
practical
implications
therapeutic
interventions.
Furthermore,
intricate
interplay
individualized
techniques
structured
methodologies
examined,
emphasizing
potential
for
holistic
treatment
paradigm,
thereby
enhancing
outcomes
fostering
individual
resilience.
Medicina,
Год журнала:
2024,
Номер
60(2), С. 285 - 285
Опубликована: Фев. 7, 2024
Chronic
stress
and
chronic
pain
share
neuro-anatomical,
endocrinological,
biological
features.
However,
prepares
the
body
for
challenging
situations
or
mitigates
tissue
damage,
while
is
an
unpleasant
sensation
due
to
nociceptive
receptor
stimulation.
When
chronic,
it
might
lead
allostatic
overload
in
brain
dysregulation
of
physiological
systems
that
are
normally
involved
adapting
environmental
challenges.
Managing
(CP)
neurorehabilitation
presents
a
significant
challenge
healthcare
professionals
researchers,
as
there
no
definitive
effective
solution
these
issues.
Patients
suffering
from
neurological
disorders
often
complain
CP,
which
significantly
reduces
their
quality
life.
The
aim
this
narrative
review
examine
correlation
between
potential
negative
impact
on
rehabilitation
process.
Moreover,
we
described
most
relevant
interventions
used
manage
population.
In
conclusion,
sheds
light
connection
pathway.
Our
results
emphasize
need
tailored
protocols
effectively
pain,
improve
treatment
adherence,
ensure
comprehensive
patient
care.
Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Март 12, 2024
Abstract
Detecting
and
responding
to
threat
engages
several
neural
nodes
including
the
amygdala,
hippocampus,
insular
cortex,
medial
prefrontal
cortices.
Recent
propositions
call
for
integration
of
more
distributed
that
process
sensory
cognitive
facets
related
threat.
Integrative,
sensitive,
reproducible
decoders
detection
response
safety
have
yet
be
established.
We
combine
functional
MRI
data
across
varying
conditioning
negative
affect
paradigms
from
1465
participants
with
multivariate
pattern
analysis
investigate
representations
safety.
The
trained
sensitively
specifically
distinguish
between
cues
multiple
datasets.
further
show
many
dynamically
shift
Our
results
establish
integrate
circuits,
merging
well-characterized
‘threat
circuit’
nodes,
discriminating
regardless
experimental
designs
or
acquisition
parameters.
Human Brain Mapping,
Год журнала:
2024,
Номер
45(4)
Опубликована: Март 1, 2024
Abstract
Studies
of
affective
neuroscience
have
typically
employed
highly
controlled,
static
experimental
paradigms
to
investigate
the
neural
underpinnings
threat
and
reward
processing
in
brain.
Yet
our
knowledge
more
naturalistic
settings
remains
limited.
Specifically,
studies
generally
examine
features
separately
under
brief
time
periods,
despite
fact
that
nature
organisms
are
often
exposed
simultaneous
presence
for
extended
periods.
To
study
mechanisms
distinct
temporal
profiles,
we
created
a
modified
version
PACMAN
game
included
these
environmental
features.
We
also
conducted
two
automated
meta‐analyses
compare
findings
from
semi‐naturalistic
paradigm
those
constrained
experiments.
Overall,
results
revealed
distributed
system
regions
sensitive
imminence
less
related
imminence,
both
which
exhibited
overlap
yet
neither
involved
amygdala.
Additionally,
systems
broadly
overlapped
with
corresponding
meta‐analyses,
notable
absence
amygdala
findings.
Together,
suggest
shared
salience
reveals
heightened
sensitivity
toward
threats
compared
rewards
when
simultaneously
present
an
environment.
The
broad
correspondence
consisting
tightly
controlled
paradigms,
illustrates
how
can
corroborate
previous
literature
while
potentially
uncovering
novel
resulting
nuances
contexts
manifest
such
dynamic
environments.
Journal of Behavioral Medicine,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 9, 2025
Abstract
Anxiety
disorders
and/or
depressive
co-occurring
with
hematological
cancer
are
an
additional
burden
for
patients.
Experiential
avoidance
(EA;
efforts
to
avoid
negative
emotions,
thoughts,
or
memories)
is
empirically
evident
transdiagnostic
factor
the
onset
and
maintenance
of
anxiety
in
non-cancer
populations.
There
lack
evidence
on
impact
EA
predicting
depression
A
total
291
patients
(60%
male,
mean
age
55
years)
were
included
this
cross-sectional
observational
study.
Participants
assessed
using
Structured
Clinical
Interview
DSM-5
mental
(SCID-5).
was
via
self-report
Brief
Avoidance
Questionnaire
(BEAQ).
Hierarchical
binomial
logistic
regression
conducted
order
estimate
disorders.
38
(13.3%)
met
diagnostic
criteria
a
current
disorder,
while
49
(17.2%)
disorder.
In
bivariate
analyses,
significantly
elevated
disorder
comparison
those
without
(54.4
vs.
48.9;
p
=
0.01).
The
same
true
(54.9
48.6;
<
After
controlling
relevant
sociodemographic
medical
factors,
did
not
predict
separate
models.
presence
predicted
by
female
sex,
younger
comorbidity
burden.
contrast,
Sociodemographic
predictors
have
greater
predictive
potential
than
regarding
